Ninth International Primary Hyperoxaluria Workshop

第九届国际原发性高草酸尿症研讨会

• 批准号: 8007053
• 负责人: ROSS P HOLMES
• 金额: $ 2万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8007053
• 关键词: Affect; Calculi; Cessation of life; Childhood; Clinical Management; Collaborations; Congresses; Diagnosis; Disease; Drug Formulations; Educational workshop; Environment; Etiology; Family; Fostering; Friends; Functional disorder; Funding; Goals; Hereditary Disease; Individual; International; Kidney Diseases; Kidney Failure; Knowledge; Laboratory Research; Lead; Nephrology; New York; Oxalates; Pathogenesis; Patients; Physicians; Primary Hyperoxaluria; Research; Research Personnel; Resource Sharing; Running; Scientist; Symptoms; improved; insight; meetings; novel; premature; public health relevance; pyridoxine; treatment strategy

DESCRIPTION (provided by applicant): Primary Hyperoxaluria is a rare genetic disease that often results in kidney failure and premature death. It often has a late diagnosis due to the similarity of symptoms to stone disease and other kidney diseases. There is no known cure apart from a small percentage of individuals who respond completely to pyridoxine therapy. The 9th International Primary Hyperoxaluria Workshop will be held in New York in August 2010 as a satellite meeting of the 15th Congress of the International Pediatric Nephrology Association. The Workshop has been held every 2 - 3 years since 1990 and represents the only meeting where scientists and physician scientists meet to specifically discuss all issues related to the diagnosis, therapy and pathophysiology of the disease. This meeting has been an invaluable resource for sharing information, fostering new ideas and forming collaborations. This meeting will be the first to be held conjointly with the IPNA meeting and will provide a unique opportunity to educate pediatric nephrologists on all aspects of the disease, but particularly its diagnosis and treatment. One half day session run in parallel will be devoted to educating affected individuals and their families on relevant aspects of the disease. Funds are requested to assist the Workshop in meeting its goals of (1) Bringing together basic scientists and physician scientists with a range of expertises to discuss current ideas on the causes, diagnosis and treatment of the primary hyperoxalurias. (2) Providing a venue and environment that encourages scientific interactions. (3) Promoting the dissemination of ideas and research strategies, that might lead to novel insights into the etiology and pathogenesis of the primary hyperoxalurias and the formulation of new treatment strategies. (4) Facilitating the entry of new, young researchers into the field of primary hyperoxaluria and other oxalate-related diseases. (5) Informing PH patients, families and friends of the latest advances in our understanding and clinical management of PH. PUBLIC HEALTH RELEVANCE: Primary Hyperoxaluria is a rare genetic disease that is studied in a limited number of research laboratories around the globe. This meeting will bring these investigators together to discuss the latest advances. The knowledge exchanged, the ideas generated, and the collaborations formed should lead to novel information that can be used to improve the diagnosis and treatment of the disease as well as increasing our understanding of its pathophysiology.

描述（由申请人提供）：原发性高黄油是一种罕见的遗传疾病，通常会导致肾衰竭和过早死亡。由于症状与石材疾病和其他肾脏疾病的相似性，因此通常有较晚的诊断。除了少量对吡啶醇疗法反应的人以外，还没有已知的治疗方法。第9届国际高氧化尿液研讨会将于2010年8月在纽约举行，作为国际儿科肾脏病学会第15届国会大会的卫星会议。该研讨会自1990年以来每2 - 3年举行一次，代表了科学家和医师科学家开会的唯一会议，专门讨论与该疾病的诊断，治疗和病理生理学有关的所有问题。这次会议一直是共享信息，促进新想法和成立协作的宝贵资源。这次会议将是第一次与iPNA会议共同举行的会议，并将提供独特的机会，以教育儿科肾病学家就疾病的各个方面，尤其是其诊断和治疗。同半天的会议并联将致力于教育受影响的个人及其家人有关疾病的相关方面。要求资金帮助研讨会实现其目标（1）将基础科学家和医师科学家汇集在一起​​，以讨论有关原发性高氧化尿液的原因，诊断和治疗的当前思想。 （2）提供鼓励科学互动的场所和环境。 （3）促进思想和研究策略的传播，这可能会导致对主要高氧化盐的病因和发病机理的新见解以及新治疗策略的制定。 （4）促进新的，年轻的研究人员进入原发性高黄油和其他与草酸盐有关的疾病领域。 （5）向pH患者，家人和朋友告知我们对PH的理解和临床管理方面的最新进展。 公共卫生相关性：原发性高黄油是一种罕见的遗传疾病，在全球的许多研究实验室中进行了研究。这次会议将使这些调查人员聚集在一起，讨论最新进展。交流的知识，产生的思想以及形成的合作应导致新的信息，这些信息可用于改善疾病的诊断和治疗，并增加我们对其病理生理学的理解。