Mount Desert Island Stem Cell Symposium

山漠岛干细胞研讨会

• 批准号: 8005471
• 负责人: LEONARD Ira ZON
• 金额: $ 1.1万
• 依托单位: MOUNT DESERT ISLAND BIOLOGICAL LAB
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8005471
• 关键词: 8 year old; Address; Animal Model; Area; Biological; Clinical; Clinical Investigator; Communities; Development; Disease; Epigenetic Process; Faculty; Fishes; General Population; Generations; Genetic Transcription; Human; Invertebrates; Island; Laboratories; Maine; Medical center; Mus; National Institute of General Medical Sciences; Natural regeneration; Nature; Regulation; Research; Research Institute; Research Personnel; Role; Scientific Advances and Accomplishments; Stem Cell Research; Stem cells; Therapeutic; Tissues; Work; Yeasts; Zebrafish; base; comparative; fly; human stem cells; interest; lectures; meetings; mouse model; novel therapeutic intervention; nuclear reprogramming; programs; public health relevance; research study; stem; stem cell biology; stem cell differentiation; stem cell therapy; symposium; tissue regeneration

DESCRIPTION (provided by applicant): The Mount Desert Island Biological Laboratory (MDIBL), The Jackson Laboratory (JAX), and the Maine Medical Center Research Institute (MMCRI) propose to continue the eight-year-old Mount Desert Island Stem Cell Symposium with three annual meetings from 2010 to 2012 with support from the National Institute of General Medical Sciences. The proposed symposia, to be held annually in August 2011, 2012, and 2013 at the Mount Desert Island Biological Laboratory in Salisbury Cove, Maine, will be the 9th, 10th, and 11th Mount Desert Island Stem Cell Symposia since the meeting was established in August 2002. The 2010 Symposium on 'Reprogramming and Epigenetics', will be held August 6 - 7, 2010. The Mount Desert Island Stem Cell Symposium will emphasize epigenetics and nuclear reprogramming in the generation and differentiation of stem cells, and the role of stem and progenitor cells in tissue regeneration. The conference will continue to engage the research strengths of MDIBL, JAX, and MMCRI by emphasizing comparative stem cell research in human, mouse, fish, and invertebrates, a programmatic approach unique to this meeting. The Organizing Committee, comprised of national leaders in biomedical and stem cell research, has developed the program of this symposium to address topical issues important to the stem cell research community. The specific aims of the 2010 symposium are: 1.) Present and discuss research studies of epigenetic regulation of gene transcription and expression in stem cells; 2.) Present and discuss scientific advances in nuclear reprogramming; 3.) Present and discuss research studies of stem cells in tissue development and regeneration; 4.) Present and discuss research in which comparative models (mouse, zebrafish, worm, fly, yeast) are utilized to study epigenetic regulation; and 5.) Provide substantial opportunities for interaction between trainees, investigators new to stem cell research, and investigators well established in these research areas. Scientific sessions will include platform presentations, a trainee/faculty networking lunch, and a lecture open to the general public. PUBLIC HEALTH RELEVANCE: The Mount Desert Island Stem Cell Symposium convenes leading investigators whose work in stem cell biology is focused on a variety of model organisms including human. The comparative nature of the meeting represents the critical need for a broad-based understanding of stem cell biology required to advance the use of human stem cells in new therapeutic approaches to disease. The invited speakers (and the organizing committee) include many clinical investigators interested in therapeutic applications of stem cell research. Their clinical interests keep stem cell therapies at the forefront of the discussion.

描述（由申请人提供）：山漠岛生物实验室 (MDIBL)、杰克逊实验室 (JAX) 和缅因州医学中心研究所 (MMCRI) 提议继续举办八年之久的山漠岛干细胞研讨会2010年至2012年在国家普通医学科学研究所的支持下举办了三届年会。拟议的研讨会将于 2011 年 8 月、2012 年和 2013 年每年在缅因州索尔兹伯里湾的沙漠岛生物实验室举行，这将是自 2011 年会议成立以来的第 9 届、第 10 届和第 11 届沙漠岛干细胞研讨会。 2002年8月。2010年“重编程和表观遗传学”研讨会将于8月6日举行- 2010 年 7 月。山漠岛干细胞研讨会将强调干细胞生成和分化中的表观遗传学和核重编程，以及干细胞和祖细胞在组织再生中的作用。会议将继续发挥 MDIBL、JAX 和 MMCRI 的研究优势，强调人类、小鼠、鱼类和无脊椎动物的比较干细胞研究，这是本次会议独有的计划方法。组委会由生物医学和干细胞研究领域的国家领导人组成，制定了本次研讨会的议程，以解决对干细胞研究界重要的热点问题。 2010年研讨会的具体目标是： 1.) 展示并讨论干细胞基因转录和表达的表观遗传调控的研究； 2.) 展示并讨论核重编程方面的科学进展； 3.) 介绍并讨论干细胞在组织发育和再生中的研究； 4.) 展示并讨论利用比较模型（小鼠、斑马鱼、蠕虫、苍蝇、酵母）来研究表观遗传调控的研究； 5.) 为受训者、刚接触干细胞研究的研究者以及在这些研究领域已经成熟的研究者之间提供大量的互动机会。科学会议将包括平台演示、实习生/教职员工网络午餐以及向公众开放的讲座。 公共健康相关性：沙漠岛干细胞研讨会聚集了干细胞生物学领域的主要研究人员，他们的工作重点是包括人类在内的各种模型生物体。此次会议的比较性质表明，迫切需要对干细胞生物学有广泛的了解，以推进人类干细胞在新的疾病治疗方法中的应用。受邀演讲者（和组委会）包括许多对干细胞研究的治疗应用感兴趣的临床研究人员。他们的临床兴趣使干细胞疗法始终处于讨论的前沿。