Mount Desert Island Stem Cell Symposium

山漠岛干细胞研讨会

• 批准号: 8005471
• 负责人: LEONARD Ira ZON
• 金额: $ 1.1万
• 依托单位: MOUNT DESERT ISLAND BIOLOGICAL LAB
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8005471
• 关键词: 8 year old; Address; Animal Model; Area; Biological; Clinical; Clinical Investigator; Communities; Development; Disease; Epigenetic Process; Faculty; Fishes; General Population; Generations; Genetic Transcription; Human; Invertebrates; Island; Laboratories; Maine; Medical center; Mus; National Institute of General Medical Sciences; Natural regeneration; Nature; Regulation; Research; Research Institute; Research Personnel; Role; Scientific Advances and Accomplishments; Stem Cell Research; Stem cells; Therapeutic; Tissues; Work; Yeasts; Zebrafish; base; comparative; fly; human stem cells; interest; lectures; meetings; mouse model; novel therapeutic intervention; nuclear reprogramming; programs; public health relevance; research study; stem; stem cell biology; stem cell differentiation; stem cell therapy; symposium; tissue regeneration

DESCRIPTION (provided by applicant): The Mount Desert Island Biological Laboratory (MDIBL), The Jackson Laboratory (JAX), and the Maine Medical Center Research Institute (MMCRI) propose to continue the eight-year-old Mount Desert Island Stem Cell Symposium with three annual meetings from 2010 to 2012 with support from the National Institute of General Medical Sciences. The proposed symposia, to be held annually in August 2011, 2012, and 2013 at the Mount Desert Island Biological Laboratory in Salisbury Cove, Maine, will be the 9th, 10th, and 11th Mount Desert Island Stem Cell Symposia since the meeting was established in August 2002. The 2010 Symposium on 'Reprogramming and Epigenetics', will be held August 6 - 7, 2010. The Mount Desert Island Stem Cell Symposium will emphasize epigenetics and nuclear reprogramming in the generation and differentiation of stem cells, and the role of stem and progenitor cells in tissue regeneration. The conference will continue to engage the research strengths of MDIBL, JAX, and MMCRI by emphasizing comparative stem cell research in human, mouse, fish, and invertebrates, a programmatic approach unique to this meeting. The Organizing Committee, comprised of national leaders in biomedical and stem cell research, has developed the program of this symposium to address topical issues important to the stem cell research community. The specific aims of the 2010 symposium are: 1.) Present and discuss research studies of epigenetic regulation of gene transcription and expression in stem cells; 2.) Present and discuss scientific advances in nuclear reprogramming; 3.) Present and discuss research studies of stem cells in tissue development and regeneration; 4.) Present and discuss research in which comparative models (mouse, zebrafish, worm, fly, yeast) are utilized to study epigenetic regulation; and 5.) Provide substantial opportunities for interaction between trainees, investigators new to stem cell research, and investigators well established in these research areas. Scientific sessions will include platform presentations, a trainee/faculty networking lunch, and a lecture open to the general public. PUBLIC HEALTH RELEVANCE: The Mount Desert Island Stem Cell Symposium convenes leading investigators whose work in stem cell biology is focused on a variety of model organisms including human. The comparative nature of the meeting represents the critical need for a broad-based understanding of stem cell biology required to advance the use of human stem cells in new therapeutic approaches to disease. The invited speakers (and the organizing committee) include many clinical investigators interested in therapeutic applications of stem cell research. Their clinical interests keep stem cell therapies at the forefront of the discussion.

描述（由申请人提供）：荒岛山生物实验室（MDIBL），杰克逊实验室（JAX）和缅因州医学中心研究所（MMCRI）提议在2010年至2012年的2012年，由美国国家一般医学科学学院的支持，继续举行了八年历史的荒岛山干细胞研讨会，并举行了三场年度会议。拟议的研讨会将于2011年8月，2012年和2013年在缅因州索尔兹伯里山山的山山山岛生物实验室举行，将是自2002年8月建立以来的第9，第10和11号山荒岛干细胞牢房。在干细胞的产生和分化中的表观遗传学和核重编程，以及干细胞和祖细胞在组织再生中的作用。会议将继续通过强调人类，老鼠，鱼类和无脊椎动物的比较干细胞研究来继续参与MDIBL，JAX和MMCRI的研究优势，这是这次会议独有的程序化方法。由国家生物医学和干细胞研究领域的国家领导人组成的组织委员会开发了该研讨会的计划，以解决对干细胞研究社区重要的主题问题。 2010年研讨会的具体目的是：1。）出现并讨论了干细胞基因转录和表达表观遗传调节的研究； 2.）提出并讨论核重编程的科学进步； 3.）提出并讨论对组织发育和再生中干细胞的研究； 4.）进行并讨论研究，其中使用比较模型（小鼠，斑马鱼，蠕虫，蝇，酵母）来研究表观遗传调节；和5.）为学员之间的互动提供了实质性的机会，这些研究人员是干细胞研究的新手研究人员，并在这些研究领域建立了良好的研究者。科学会议将包括平台演讲，实习生/教师网络午餐以及向公众开放的演讲。 公共卫生相关性：荒岛山干细胞研讨会召集了领先的研究人员，他们的干细胞生物学工作集中在包括人类在内的各种模型生物上。会议的比较性质代表了对在新的治疗方法中促进人类干细胞的使用所需的对干细胞生物学的广泛理解的关键需求。受邀发言人（和组织委员会）包括许多对干细胞研究治疗应用感兴趣的临床研究者。他们的临床利益使干细胞疗法处于讨论的最前沿。