2015 Stem Cells & Cancer Gordon Research Conference & Gordon Research Seminar

2015年干细胞

• 批准号: 8827034
• 负责人: LEONARD Ira ZON
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-02-10 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8827034
• 关键词: Aging; Biology; Blastoma; Cancer Biology; Clonal Evolution; Clonality; Colon Carcinoma; Epigenetic Process; Europe; Goals; Hematopoiesis; Heterogeneity; International; Knowledge; Lead; Malignant Neoplasms; Malignant Squamous Cell Neoplasm; Montana; Myomatous neoplasm; Neoplasm Metastasis; Organ; Play; Postdoctoral Fellow; Process; Research; Role; Stem cells; Students; Switzerland; Therapeutic; Work; abstracting; anticancer research; cancer cell; cancer stem cell; epigenetic regulation; interest; leukemia; leukemia/lymphoma; malignant breast neoplasm; meetings; melanoma; programs; public health relevance; stem cell biology; symposium; targeted treatment; therapy resistant; tumor

 DESCRIPTION (provided by applicant): The Fifth Gordon Conference on Stems Cells and Cancer will focus on understanding how cancer stem cells behave and interact with their niche. There is a tremendous interest in heterogeneity among cancer cells as clonal evolution occurs in tumors. A number of new therapies have been sought to counter particularly aspects of this heterogeneity. Tumors will be investigated including melanoma, leukemia, lymphoma, muscle tumors, colon cancer, breast cancer, squamous cell cancer, medullar blastoma, and others. There is an interest in understanding the interaction between normal stem cells and cancer biology and this will also be a goal of the meeting. Topics that will be explored at the meeting will be to examine diversity of cancer stem cells as they regulate metastasis, an understanding of normal stem cell biology including epigenetic regulation, and understanding of aging and cancer, cancer stem cell biology including clonal evolution. A therapeutic aim will be to target cancer stem cells and examine their niches. A comparison of normal hematopoiesis and stem cells in leukemia will also be discussed. There will also be a GRS associated with this conference, allowing students and postdoctoral fellows to explore aspects of cancer and stem cells with experts in the field. These talks at the GRC should allow us to have a better understanding of how cancer arises and the process by which the niche interacts.

 描述（由申请人提供）：第五届戈登干细胞与癌症会议将重点了解癌症干细胞如何表现以及与其生态位相互作用。随着肿瘤中发生克隆进化，人们对癌细胞的异质性产生了极大的兴趣。人们正在寻找新的疗法来对抗这种异质性的特定方面，将研究包括黑色素瘤、白血病、淋巴瘤、肌肉肿瘤、结肠癌、乳腺癌、鳞状细胞癌、髓母细胞瘤和其他人对了解正常干细胞与癌症生物学之间的相互作用感兴趣，这也将是会议的一个目标，会议将探讨癌症干细胞在调节转移时的多样性，了解正常干细胞生物学（包括表观遗传调控），以及了解衰老和癌症、癌症干细胞生物学（包括克隆进化）。还将讨论白血病。本次会议还将举办 GRS，让学生和博士后研究员与该领域的专家探讨癌症和干细胞的各个方面，GRC 上的这些演讲应该让我们更好地了解癌症是如何产生的以及过程。利基通过它相互作用。