MOLECULAR BIOLOGY-BIOCHEMISTRY MODULE

分子生物学-生物化学模块

• 批准号: 8047986
• 负责人: MAUREEN E NEITZ
• 金额: $ 18.09万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8047986
• 关键词: Advisory Committees; Biochemical; Biochemistry; Clinical Research; Faculty; Human; Human Subject Research; Methods; Molecular; Molecular Biology; Names; Participant; Patients; Procedures; Protocols documentation; Records; Recruitment Activity; Research; Research Personnel; Resources; Sampling; Technology; Time; genetic analysis; human subject; instrument; response

The functions of this Module have evolved over the years in response to changing technology and therefore the changing needs of our group. The Module was originally established as a Biochemistry Module. Three cycles ago when molecular methods came into widespread use, a molecular biology component was added making it the Biochemistry-Molecular Biology Module. Now the order of "Molecular Biology" and "Biochemistry" in the Module name has been reversed to reflect that the use of molecular methods is currently the major activity of the Module. The Module does, however, continue to provide the biochemistry resources that are needed by the participating faculty. This is one of our most heavily used Modules. Its major functions are to provide shared-use instruments for molecular and biochemical analyses that are well maintained and accessible, and to provide skilled technical support to perform a variety of commonly used protocols. There is also an important instructional component to the Module: the Module directors help Core participants develop molecular approaches for answering their research questions, and together the Module directors and technician instruct investigators and their staff in the practical aspects of the experimental procedures and instrument use. In response to the expanding use of the Module for genetic analysis of human samples, we plan to add a part time clinical research coordinator to the Module staff. Access to help with human subjects research was identified by the Core Advisory Committee as the most pressing new staffing need in our Core Modules. With the addition of a clinical research coordinator, this Module will therefore be able to assist investigators with drafting human subjects protocols and with all aspects of recruiting subjects, obtaining samples, and managing patient records.

多年来，该模块的功能已随着 不断变化的技术，因此我们小组的需求不断变化。该模块最初是作为一个 生物化学模块。三个周期前，当分子方法广泛使用时，一种分子生物学 添加了成分，使其成为生物化学 - 分子生物学模块。现在“分子” 模块名称中的生物学”和“生物化学”已逆转以反映出分子方法的使用是 目前，该模块的主要活动。但是，该模块确实继续提供生物化学 参与教师所需的资源。 这是我们使用最广泛的模块之一。它的主要功能是为 可以很好地维护和访问的分子和生化分析，并提供熟练的技术 支持执行各种常用协议。还有一个重要的教学组成部分 模块：模块主管帮助核心参与者开发分子方法来回答他们的 研究问题，以及模块董事和技术人员一起指导研究人员及其员工 实验程序和仪器使用的实际方面。 为了响应扩展的模块用于人类样品的遗传分析的使用，我们计划添加一个 兼职临床研究协调员的模块工作人员。获得人类受试者研究的帮助是 核心咨询委员会确定为我们核心模块中最紧迫的人员需求。与 因此，增加了临床研究协调员，因此该模块将能够协助研究人员起草 人类主题协议以及招聘主题的各个方面，获取样本和管理患者 记录。