CCASAnet: Caribbean, Central and South America Network

CCASAnet：加勒比海、中美洲和南美洲网络

• 批准号: 7927754
• 负责人: CATHERINE C MCGOWAN
• 金额: $ 29.36万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-22 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7927754
• 关键词: Address; Argentina; Arts; Biometry; Brazil; Caribbean region; Chile; Clinical Data; Clinical Research; Collaborations; Data; Data Set; Databases; Development; Elements; Epidemiology; HIV; Haiti; Honduras; Information Sciences; International; Meta-Analysis; Methods; Peru; Publications; Publishing; Research; Research Activity; Research Infrastructure; Research Personnel; Resources; Science; Site; Source; South America; Structure; Technology; Training; Universities; base; clinical practice; clinical research site; data sharing; improved; programs; tool

DESCRIPTION (provided by applicant): The Caribbean, Central and South America network for HIV epidemiology (CCASAnet) brings together the clinical and data expertise and resources of Vanderbilt University and clinical sites in Argentina, Brazil, Chile, Haiti, Honduras, and Peru. CCASAnet will use state-of-the-art technologies to create a shared data repository and associated methods for data merging that forms the union of existing HIV-related clinical data sets available at the participating sites. The project will conduct and facilitate research using the shared data repository that enables answers to questions that cannot be answered by any single source, and develop and evaluate new biostatistics methods relevant to HIV epidemiology. CCASAnet will develop and conduct a program of face-to-face and educational and training based on International Good Clinical Practice standards that will assist sites to improve the quality and consistency of their clinical research activities. The CCASAnet Coordinating Center will provide an infrastructure for review and approval of data use requests, create end-user data access tools that facilitate research using the shared data repository, and assist investigators with analysis and publication of research findings. CCASAnet will also participate with other regional IEDEA networks in the development of international standards for sharing and meta-analysis of HIV-related data. By these activities, CCASAnet will help advance both the science of HIV epidemiology, and the information science that underpins international research collaboration.

描述（由申请人提供）：加勒比、中美洲和南美洲艾滋病毒流行病学网络 (CCASAnet) 汇集了范德比尔特大学以及阿根廷、巴西、智利、海地、洪都拉斯和秘鲁临床中心的临床和数据专业知识和资源。 CCASAnet 将使用最先进的技术创建一个共享数据存储库和相关的数据合并方法，形成参与站点现有的艾滋病毒相关临床数据集的联合体。该项目将利用共享数据存储库开展和促进研究，从而回答任何单一来源无法回答的问题，并开发和评估与艾滋病毒流行病学相关的新生物统计方法。 CCASAnet 将根据国际药品临床试验质量管理规范标准制定并开展面对面的教育和培训计划，帮助研究中心提高其临床研究活动的质量和一致性。 CCASAnet协调中心将提供用于审查和批准数据使用请求的基础设施，创建最终用户数据访问工具以促进使用共享数据存储库的研究，并协助研究人员分析和发布研究结果。 CCASAnet 还将与其他区域 IEDEA 网络一起参与制定艾滋病毒相关数据共享和荟萃分析的国际标准。通过这些活动，CCASAnet 将帮助推进艾滋病毒流行病学科学和支撑国际研究合作的信息科学。