Community Liaison and Recruitment Core (CLRC)

社区联络和招聘核心 (CLRC)

基本信息

批准号：
10729793
负责人：
JIN HUI JOO
金额：
$ 12.24万
依托单位：
MASSACHUSETTS GENERAL HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-01 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10729793
关键词：
Address Adult Aging Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Area Behavior Therapy Behavioral Research Black Populations Black race Boston Caregivers Caring Collaborations Common Data Element Communities Consensus Data Data Element Dementia Development Educational Curriculum Enrollment Evaluable Disease Evaluation Event Federally Qualified Health Center Fostering Funding Future Health Health Personnel Hospitals Individual Intervention Studies Latino Latino Population Learning Massachusetts Measures Mentors Methods Minority Minority Groups Minority Health Research Modeling Neighborhoods New England Newsletter Ontology Participant Patients PhenX Toolkit Pilot Projects Population Prevention Procedures Protocols documentation Publishing Randomized Reporting Research Research Personnel Resources Risk Science Scientist Sequential Multiple Assignment Randomized Trial Series Site Statistical Methods Telephone Testing Training Translating Trust United States National Institutes of Health Universities Work behavioral health community engagement comparative effectiveness dementia risk digital education research health disparity health empowerment high risk implementation evaluation literacy member participant enrollment personalized approach primary outcome recruit recruitment science retention rate screening social health determinants trial design

项目摘要

Although minority populations – particularly Black and Latino adults – have the highest rates and are at highest risk for Alzheimer’s disease and related dementias (ADRD), to date inclusion of these populations (patients, care partners and dyads) in ADRD research remains low and inconsistent. Testable, scalable methods are urgently needed, founded on a science of ADRD diversity to drive quantifiable, precision approaches in recruitment, engagement, and retention (RER). Community engagement and study enrollment barriers, already multi-factorial, are compounded for Black and Latino populations, limiting researchers’ ability to address health disparities in ADRD. Without critical developments in RER science, investigators risk exacerbating – or worse, misunderstanding – existing health disparities in ADRD and ADRD research by failing to include Black and Latino communities in cutting-edge ADRD behavioral health research. The Community Liaison & Recruitment Core (CLRC) activities are directly aligned with the Mass-ENVISION theme to provide resources, training, and sustained and tailored mentoring to UiM scientists in ADRD-related behavioral interventions following the NIH Stage Model, the NIA Health Disparities Framework, and the CDC and NAM prevention frameworks, in both community and hospital settings. The CLRC will advance the science of diversity in ADRD behavioral interventions research via 4 Specific Aims: 1) Operationalize a precision science of diverse recruitment, engagement, and retention into ADRD research; 2) Convene a stakeholder group of Black and Latino individuals to determine optimal recruitment and engagement strategies for these populations in ADRD behavioral interventions research; 3) Provide RCMAR Scientists with practical examples of RER strategies in a separately funded digitized trial to be launched at Whittier Street Health Center, a local Federally Qualified Health Center; 4) Train and provide sustained and tailored mentoring of RCMAR Scientists in a community-engaged science of recruitment, engagement, and retention. The CLRC is led by Dr. Jonathan Jackson, an expert in ADRD and methods for recruitment, engagement and retention of minority populations in research. The CLRC will foster crosspollination of resources with the Massachusetts Alzheimer’s Research Center (MADRC) and Boston University Alzheimer’s Research Center (BU-ADRC) and will establish and grow community collaborations across the Massachusetts and larger New England areas.

尽管少数族裔——尤其是黑人和拉丁裔成年人——的患病率最高且风险最高阿尔茨海默氏病和相关痴呆症 (ADRD)，迄今为止已纳入这些人群（患者、护理伙伴和 ADRD 研究中的二元组）仍然很低且不一致，迫切需要建立在以下基础上的可测试的、可扩展的方法。 ADRD 多样性科学推动招聘、敬业度和保留 (RER) 方面可量化、精确的方法。社区参与和学习入学障碍本已是多因素的，对于黑人和拉丁裔来说更加复杂如果 RER 没有取得重大进展，研究人员解决 ADRD 健康差异的能力就会受到限制。科学，研究人员可能会检查（或更糟糕的是，误解）ADRD 和 ADRD 中现有的健康差异未能将黑人和拉丁裔社区纳入前沿的 ADRD 行为健康研究。社区联络和招聘核心 (CLRC) 活动与 Mass-ENVISION 主题直接相关，以提供为密歇根大学科学家提供 ADRD 相关行为干预方面的资源、培训以及持续和量身定制的指导遵循 NIH 阶段模型、NIA 健康差异框架以及 CDC 和 NAM 预防框架， CLRC 将在社区和医院环境中推进 ADRD 行为干预的多样性科学。研究通过 4 个具体目标：1) 将多样化招聘、参与和保留的精准科学运用到 ADRD 研究；2) 召集一个由黑人和拉丁裔人士组成的利益相关者小组来确定最佳招募和 ADRD 行为干预研究中这些人群的参与策略；3) 提供 RCMAR 科学家包含将在 Whittier Street Health 启动的单独资助的数字化试验中 RER 策略的实例中心，当地联邦合格的健康中心；4) 为 RCMAR 提供持续和定制的指导； CLRC 的科学家由乔纳森博士领导，从事社区参与的招募、参与和保留科学工作。 Jackson 是 ADRD 以及少数族裔研究招募、参与和保留方法方面的专家。 CLRC 将促进与马萨诸塞州阿尔茨海默病研究中心 (MADRC) 和波士顿大学阿尔茨海默病研究中心 (BU-ADRC) 将建立和发展社区合作马萨诸塞州和更大的新英格兰地区。