Program Administration and Data IVIanagement

项目管理和数据管理

• 批准号: 7854617
• 负责人: JAMES Ivan MULLINS
• 金额: $ 36.42万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-15 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7854617
• 关键词: Arts; Biological Assay; Biostatistics Core; Clinical; Collaborations; Communication; Complex; Data; Data Analyses; Databases; Development; Discipline; Disease Management; Disease Progression; HIV Infections; HIV-1; Human; Infection; International; Investigation; Laboratories; Leadership; Methods; Participant; Relative (related person); Research; Research Personnel; Retrieval; Scientist; Site; Strategic Planning; Summary Reports; Text; Time; Work; analytical tool; cohort; data acquisition; design; interest; multidisciplinary; organizational structure; programs; success; synergism; tool; vaccine development

The studies proposed within the SeaPIP are complex and multidisciplinary, and they involve multiple investigators and sites, cohorts of human participants and clinical and investigational assays. Critically, they also involve state-of-the-art investigations to facilitate additional understanding of primary HIV-1 infection and to provide important information needed to advance concepts and methods for ultimately blocking the establishment of HIV-1 infection and disease progression. Logistical support, coordination, and synergism between such complex studies are crucial to the success of the overall research program. Hence, a significant amount of time and effort of Dr. Muliins and his team, assisted by Dr. Collier and working with collaborating investigators and staff in other Projects and Cores, will be devoted to this endeavor. In addition to standard administrative and fiscal management functions, this core will be responsible for bringing together talented scientists and clinicians from diverse disciplines in order to develop multifaceted and uniquely synergistic studies with continual focus on aspects of primary HIV infection most critical to disease management and vaccine development. This core will also be responsible for the development of a database to coordinate laboratory data acquisition and management (Aim 3), interfacing strongly with Clinical Core B and Biostatistics Core D. Design and application of the database and analytical tools will be driven through interaction with all SeaPIP investigators and tailored to their specific data acquisition, retrieval and analysis needs. Hence, this aspect of the core will also interact closely and continuously with each of the other projects and cores to acquire, access and analyze data. To further enhance investigator synergy, a summary-reporting feature will be built into the database to prompt interested investigators to access detailed progress within each Project and Core and prompt ideas for new or expanded investigations.

SEAPIP内提出的研究是复杂且多学科的，它们涉及多个 研究人员和站点，人类参与者的同类以及临床和研究测定法。至关重要的是，它们还涉及最新的研究，以促进对原发性HIV-1感染的更多了解，并提供推进概念和方法最终阻止HIV-1感染和疾病进展所需的重要信息。这种复杂研究之间的后勤支持，协调和协同作用对于整体研究计划的成功至关重要。因此，Muliins博士及其团队的大量时间和精力在Collier博士的协助下，并与其他项目和核心的调查人员和员工合作，将致力于这项工作。 除了标准的行政和财政管理职能外，该核心还将负责将来自不同学科的才华横溢的科学家和临床医生汇集在一起​​，以开发多方面和独特的协同研究，并不断关注原发性HIV感染方面最关键的疾病管理和疫苗管理和疫苗疫苗最重要的方面发展。该核心还将负责开发数据库，​​以协调实验室数据获取和管理（AIM 3），与临床核心B和生物统计学核心D强烈接口D.数据库的设计和应用以及分析工具将通过与互动来驱动与分析工具的相互作用。所有SEAPIP研究人员，并根据其特定的数据获取，检索和分析需求量身定制。因此，核心的这一方面还将与其他每个项目和内核紧密相互作用，以获取，访问和分析数据。为了进一步增强研究者的协同作用，数据库中将建立一项摘要报告功能，以提示有兴趣的研究人员在每个项目和核心中访问详细的进度，并迅速进行新的或扩展的调查想法。