Childhood socioeconomic disadvantage, cumulative Adverse Childhood Experiences, and adolescent depression and anxiety symptoms

童年社会经济劣势、累积的不良童年经历以及青少年抑郁和焦虑症状

基本信息

批准号：
10676396
负责人：
Chelsea Moore
金额：
$ 4.47万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-08-28 至 2025-08-27
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10676396
关键词：
Address Adolescence Adolescent Advocacy Age Anxiety Birth Black race Child Welfare Childhood Clinical Clinical assessments Complex Data Data Set Distal Ethnic Origin Exposure to Family Fellowship Fostering Future Hispanic Household Individual Individual National Research Service Award Interpersonal Violence Knowledge Low Income Population Low income Mediating Mental Depression Mental Health Mental disorders Mentorship Methods Michigan Modeling National Research Service Awards Nursing Research Outcome Participant Personal Satisfaction Policies Poverty Prevention Prevention strategy Primary Prevention Public Health Public Policy Race Research Research Personnel Research Project Grants Resource Allocation Resources Risk Risk Factors Role Sampling Studies School Nursing Schools Shapes Social Work Statistical Models Strategic Planning Surgeon Surveys Techniques Time Training Trauma United States Universities Update Work Youth abuse neglect adolescent health adverse childhood events anxiety symptoms biological sex career child depression child poverty childhood adversity depressive symptoms early childhood ethnic diversity experience faculty mentor health equity implementation intervention insight pre-doctoral programs racial diversity secondary analysis skills social social factors social health determinants socioeconomic disadvantage suicidal

项目摘要

Project Summary/Abstract. Cumulative Adverse Childhood Experiences (ACEs) and childhood socioeconomic disadvantage (SED) have each been identified as major contributors to poor adolescent mental health and have been associated with one another. However, less is known about how cumulative ACEs and childhood SED operate together to influence adolescent mental health, resulting in disagreement among childhood adversity researchers. Without a clearer understanding of this complex relationship, we risk overlooking largely impactful social factors that influence adolescent health and well-being and our efforts to address the current youth mental health crisis will be hindered. The purpose of this Ruth L. Kirschstein National Research Service Award (NRSA) Individual Pre- Doctoral Fellowship in Nursing Research (F31) application is to prepare the applicant for a career as an independent investigator focused on expanding our collective knowledge of social risk factors and informing primary prevention strategies related to childhood adversity and adolescent mental health. The proposed fellowship consists of two complementary components: 1) a training plan aimed at developing the applicant’s methods proficiency, substantive expertise, and role attainment; and 2) a research project that will further our understanding of the relationship between childhood SED, ACE exposure, and adolescent depression and anxiety. A strong mentorship team that includes sponsors and collaborators from the University of Michigan’s Schools of Nursing, Public Health, and Social Work, as well as consultants from UM’s Poverty Solutions and School of Public Policy will provide interdisciplinary expertise in childhood adversity/trauma, child poverty, youth mental health, policy advocacy, intervention implementation, and advanced statistical techniques. The proposed research project will utilize data collected as part of the large, diverse, longitudinal Fragile Families and Child Wellbeing Study from birth through age 15. The specific aims are to: 1a) Investigate for the presence of distinct profiles of ACE exposure during early childhood and how childhood SED predicts profile membership; 1b) Examine the association between distinct ACE profiles and adolescent depression and anxiety, and if childhood SED moderates these associations; and 2) Investigate for transitions in ACE profile membership during early childhood, how childhood SED influences profile transitions, and how transitions are associated with mental health. Additional exploratory analyses will be conducted to assess the influence of additional social determinants of health, including race/ethnicity and biological sex. This study aligns with the NINR’s updated strategic plan by addressing health equity through the study of key social determinants of health and well-being. Findings from this study are critical for shaping future policy and research agendas, the allocation of scarce resources, and better identifying subpopulations in the clinical setting that are at greater risk for poor mental health.

项目摘要/摘要。累积不良童年经历 (ACE) 和儿童社会经济劣势 (SED) 每一项都被确定为导致青少年心理健康状况不佳的主要因素，并且与然而，对于累积 ACE 和童年 SED 如何共同发挥作用，人们知之甚少。影响青少年的心理健康，导致儿童逆境研究人员之间存在分歧。为了更清楚地了解这种复杂的关系，我们可能会忽视那些具有很大影响力的社会因素影响青少年的健康和福祉，我们解决当前青少年心理健康危机的努力将受到阻碍。 Ruth L. Kirschstein 国家研究服务奖 (NRSA) 个人预选的目的护理研究博士奖学金（F31）申请旨在帮助申请人为作为护理人员的职业生涯做好准备独立调查员致力于扩大我们对社会风险因素的集体知识并提供信息与儿童逆境和青少年心理健康相关的初级预防策略。研究金由两个互补的部分组成：1）旨在培养申请人的培训计划方法熟练程度、实质性专业知识和角色成就；以及 2) 一个将进一步推进我们的研究项目；了解儿童 SED、ACE 暴露与青少年抑郁症之间的关系一个强大的指导团队，其中包括来自密歇根大学的赞助商和合作者。护理学院、公共卫生学院和社会工作学院，以及来自 UM 贫困解决方案和公共政策学院将提供儿童逆境/创伤、儿童贫困、青年心理健康、政策倡导、干预措施实施和先进统计技术。拟议的研究项目将利用收集的数据作为大型、多样化、纵向研究的一部分从出生到 15 岁的脆弱家庭和儿童福祉研究。具体目标是： 1a) 调查了解儿童早期 ACE 暴露的不同特征以及儿童 SED 如何预测档案成员资格；1b) 检查不同 ACE 档案与青少年抑郁症之间的关联；焦虑，以及童年 SED 是否调节这些关联；以及 2) 调查 ACE 谱的转变；幼儿期的会员资格、童年 SED 如何影响个人资料转变以及转变如何发生将进行额外的探索性分析以评估其影响。其他健康问题社会决定因素，包括种族/族裔和生物性别。本研究通过研究解决健康公平问题，与 NINR 更新的战略计划保持一致这项研究的结果对于塑造未来至关重要。政策和研究议程、稀缺资源的分配以及更好地识别该地区的亚人群心理健康状况不佳的风险更大的临床环境。