A Multilevel HIV-Prevention Strategy for High-Risk Youth

针对高危青少年的多层次艾滋病毒预防策略

• 批准号: 7867616
• 负责人: RALPH J DICLEMENTE
• 金额: $ 19.18万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-21 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7867616
• 关键词: AIDS prevention; Abstinence; Adolescent; Adoption; Affect; African American; Age; Attitude; Behavior; Belief; Chlamydia; Cities; Communities; Cross-Sectional Studies; Detection; Digit structure; Epidemic; Exhibits; Expectancy; Geographic Locations; Gonorrhea; HIV; Health Promotion; Incidence; Intervention; Joints; Low income; Maca; Mass Media; Media Campaign; Media Intervention; Mediating; Methodology; Modeling; Outcome; Patient Self-Report; Prevention strategy; Preventive; Preventive Intervention; Randomized; Randomized Controlled Clinical Trials; Recruitment Activity; Research; Research Personnel; Risk; Risk Reduction; Role; Self Efficacy; Sex Behavior; Sexually Transmitted Diseases; Specimen; Surveys; Telephone Interviews; Testing; Time; Training; Trichomonas; Urine; Youth; base; community organizations; community setting; design; disorder prevention; efficacy testing; follow-up; group intervention; high risk; intervention effect; peer; programs; protective behavior; safer sex; skills; skills training; social; therapy design; transmission process

DESCRIPTION (provided by applicant): This multisite project provides a unique test of a multilevel HIV/STD prevention strategy for high-risk youth. A total of 1600 African American adolescents, ages 12-16, will be recruited through CBOs in 4 cities, two in the Northeast (Providence and Syracuse) and two in the Southeast (Columbia and Macon), to participate in this HIV/STD prevention trial. Adolescents will complete a baseline ACASI administered survey to assess their attitudes, beliefs and sexual behaviors, and provide a urine specimen for detection of three prevalent STDs. Following baseline assessment, all adolescents will be randomly assigned to receive either the Focus on Kids HIV-prevention intervention or a General Health Promotion control. Subsequently, adolescents will be followed longitudinally and complete similar assessments at 6-, 12- and 18-months follow-up. The second level of intervention involves tailored HIV/STD prevention messages through local mass media. One city in each regional city-pair will be randomly assigned to receive the HIV prevention media campaign while the other city will serve as a control city (no media campaign). Thus, the media messages will be directed to African American youth in only one of the two cities in each geographic region. The media program will deliver HIV-prevention messages that are culturally sensitive and age appropriate; these programs will promote both abstinence and risk reduction practices. Cross-sectional surveys of 1200 African American youth using random-digit-dialing telephone interviews in the two cities that receive the media campaign and the two media control cities will be conducted over a 30-month period to determine the community-wide effects of the HIV media campaign. This design will enable a test of the joint and separate effects of the two interventions over an 18-month follow-up for the youth participating in the small-group interventions. In addition, the media campaign is predicted to independently enhance adolescents' adoption of HIV-preventive attitudes, beliefs and behaviors on a community-wide basis compared to youth in the non-media control cities. Causal modeling methodology will be employed to assess the effects of the two levels of intervention and to identify the role of supportive messages received through the media and from peers that are predicted to maintain safer sexual behavior as adolescents mature.

描述（由申请人提供）：这个多站点项目为高风险青年提供了多级HIV/STD预防策略的独特测试。 总共1600名12-16岁的非裔美国青少年将通过4个城市的CBO招募，东北两个（Providence and Syracuse）和两名在东南部（哥伦比亚和Macon）参加了这项HIV/STD预防试验。 青少年将完成一项基线ACASI管理调查，以评估其态度，信念和性行为，并提供尿液标本以检测三个普遍的性病。 在基线评估之后，所有青少年都将被随机分配，以接收对儿童预防干预或一般健康促进控制的关注。随后，将在6个，12个月和18个月的随访中纵向遵循青少年并完成类似的评估。 第二层的干预措施涉及通过当地大众媒体量身定制的HIV/STD预防信息。 每个区域城市的一个城市将被随机分配接受预防艾滋病毒的媒体运动，而另一个城市将充当控制城市（无媒体运动）。 因此，将在每个地理区域中的两个城市中的一个城市中，将向非裔美国青年进行媒体信息。媒体计划将传达对文化敏感且适合年龄的艾滋病毒预防信息；这些计划将促进戒酒和降低风险惯例。 在接受媒体运动的两个城市和两个媒体控制城市的两个城市中，对1200名非裔美国人青年进行了1200名非裔美国青年的调查，将在30个月内进行，以确定HIV媒体运动的社区范围。 该设计将对参加小组干预的年轻人进行18个月的随访，对两种干预措施的关节和单独影响进行测试。 此外，与非媒体控制城市中的青年相比，媒体运动预计将独立增强青少年采用预防态度，信念和行为。 将采用因果建模方法来评估两种干预层面的影响，并确定通过媒体收到的支持信息的作用以及预计将保持更安全的性行为作为青少年成熟的同龄人的作用。