Reducing Alcohol-Related HIV Risk in African American Females

降低非裔美国女性与酒精相关的艾滋病毒风险

基本信息

批准号：
8720488
负责人：
RALPH J DICLEMENTE
金额：
$ 65.26万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-09-30 至 2016-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8720488
关键词：
21 year old AIDS prevention Address Adopted Adverse effects African American Alcohol consumption Alcohols Anal Sex Attention Attitude Awareness Behavior Behavioral Biological Caring Centers for Disease Control and Prevention (U.S.)Coitus Communication Communities Data Decision Making Diabetes prevention Educational process of instructing Epidemic Equation Esthesia Evidence based intervention Female Frequencies Gender Glare HIV HIV Infections HIV risk HIV/STD Health Health Promotion Health Services Hispanics Incidence Infection Intervention Intervention Studies Length Literature Logistics Measures Mediating Mediator of activation protein Mental Depression Modality Outcome Participant Personal Satisfaction Play Population Predisposition Prevalence Preventive Preventive Intervention Public Health Randomized Randomized Controlled Trials Recording of previous events Recurrence Relative (related person)Reporting Research Risk Risk Behaviors Risk Factors Risk-Taking Role Self Efficacy Services Sex Behavior Sexual Health Sexual Partners Specimen Subgroup Testing Time Treatment Efficacy Vagina Videotape Violence Vulnerable Populations Woman Work Youth alcohol intervention arm avoid sex base condoms design drinking effective intervention efficacy testing evidence base follow-up high risk improved innovation intervention effect male motivational enhancement therapy post intervention programs protective behavior psychosocial public health relevance reduced alcohol use response safer sex self esteem sex sexual risk taking skills skills training therapy design treatment effect young woman

项目摘要

DESCRIPTION (provided by applicant): Young African-American women who report a higher frequency of alcohol use have markedly higher rates of STDs and HIV sex behaviors. Unfortunately, there are no evidence-based HIV interventions designed to be gender- and culturally-congruent for this population. To address this gap in the HIV intervention armamentarium, we propose to supplement a CDC-defined evidence-based intervention, Horizons, with an innovative intervention modality, Group Motivational Enhancement Therapy (GMET), which has demonstrated promise in reducing alcohol use and alcohol-related HIV risk-taking. To test the efficacy of the combined Horizons+GMET alcohol-specific module to a time-equivalent Horizons+attention control general health promotion (GHP) module focusing on diabetes prevention, and to enhanced standard-of- care. In the proposed study, 600 young African American women, 17-21 years of age, seeking sexual health services and reporting =>3 drinking occasions in the prior 60 days, will complete a baseline assessment consisting of an ACASI, videotaped communication role plays to objectively measure communication skill proficiency, and provide a vaginal specimen to assess STDs. Subsequently, they will be randomly assigned to one of three conditions: (1) Horizons+GMET alcohol-specific condition, (2) a time-equivalent Horizons+GHP condition, or (3) an enhanced standard-of-care control condition. The GMET alcohol-specific module has demonstrated evidence of efficacy in influencing several alcohol- specific constructs (attitudes, norms, self-efficacy) and reducing sexual risk-taking among culturally- diverse high-risk youth. The GMET alcohol-specific module was designed to increase woman's awareness of the adverse effects of alcohol on themselves, their sexual decision-making, and their male partner and teaches women strategies to reduce the likelihood of engaging in sex under the influence of alcohol and provides skills training needed to effectively communicate their sexual intentions to use condoms and/or refuse risky sex, when they or their male sex partner has been using alcohol. After completing the two active interventions or control condition, participants complete a brief post-test ACASI to assess immediate changes in hypothesized psychosocial mediators of safer sex and alcohol use. Subsequently, women return to complete follow-up assessments at 6-months (ACSAI and STD assessment) and 12- months (ACASI, STD assessment, objective communication skills assessment) post-intervention. An intent-to-treat analysis, using linear and logistic generalized estimating equations (GEE), will examine the efficacy of the Horizons+GMET condition in reducing incident STDs, enhancing condom-protected vaginal and anal sex acts, and enhancing alcohol-related and HIV-related mediators of HIV-preventive behaviors over the 12-month follow-up period. If the intervention is observed to be effective we will work closely with the CDC DEBI program to facilitate dissemination to public health agencies and CBOs.

描述（由申请人提供）：报告饮酒频率较高的年轻非裔美国妇女的性病和艾滋病毒性行为率明显更高。不幸的是，没有针对该人群的性别和文化范围的循证艾滋病毒干预措施。为了解决HIV干预武术中的这一差距，我们建议通过创新的干预方式补充CDC定义的基于循证的干预措施，Horizons，团体动机增强疗法（GMET），该疗法在减少酒精使用和与酒精有关的HIV相关HIV风险冒险方面表现出了希望。为了测试合并的视野+GMET酒精特异性模块对时间等效的视野+注意力控制一般健康促进（GHP）模块，以预防糖尿病预防，并增强了标准。在拟议的研究中，有600名非裔美国妇女，17-21岁，寻求性健康服务和报告=>>>> 3次饮酒场合，将完成一个基线评估，该评估包括ACASI，包括ACASI，录像的沟通角色，可以客观地衡量沟通技巧，并提供阴道标本来评估STD。随后，它们将被随机分配到三个条件之一：（1）Horizons+GMET酒精特异性条件，（2）时间等效的视野+GHP条件，或（3）增强的护理标准控制条件。 GMET酒精特异性的模块显示了影响几种酒精特定结构（态度，规范，自我效能感）和减少文化上多样化的高风险青年的性冒险的证据。 GMET酒精特异性的模块旨在提高女性对酒精对自己的不利影响，性决策和男性伴侣的不利影响的认识，并教授女性策略，以减少在酒精影响下进行性别的可能性，并提供有效的技能培训，以便有效地交流自己的性爱和/或拒绝与男性伴侣的性行为或拒绝与男性性伴侣使用的性行为。完成两种主动干预措施或控制条件后，参与者完成了简短的测试后ACASI，以评估假设的心理社会心理介导者的安全性和酒精使用情况的立即变化。随后，妇女在6个月（ACSAI和STD评估）和12个月（ACASI，STD评估，客观沟通技能评估）进行干预后返回完成后续评估。使用线性和逻辑通用估计方程（GEE）的意图对治疗分析将检查地平线+GMET条件在减少事件性传播性传播疾病中的效果，增强了避孕套保护性的阴道和肛门性行为，并增强与酒精相关的和艾滋病毒相关的艾滋病毒相关和与HIV相关的媒介物的相关性行为，使艾滋病毒相关的行为超过12个月。如果观察到干预措施有效，我们将与CDC Debi计划紧密合作，以促进向公共卫生机构和CBO传播。

项目成果

期刊论文数量（16）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Mental Representation of Self in Relationships Indirectly Affects Young Black Women's Engagement in Risky Sexual Behaviors Through Psychosocial HIV/STI Risk Factors.

DOI：
10.1080/17450128.2019.1574366
发表时间：
2019
期刊：
Vulnerable children and youth studies
影响因子：
1.1
作者：
Gause NK;Brown JL;DiClemente RJ
通讯作者：
DiClemente RJ

African American Women's Language Use in Response to Male Partners' Condom Negotiation Tactics.

非裔美国妇女使用语言来回应男性伴侣的安全套谈判策略。

DOI：
10.1080/10510974.2017.1412335
发表时间：
2018
期刊：
Communication studies
影响因子：
1.6
作者：
Li,Yachao;Samp,JenniferA;Cone,ValerieBColes;Kollar,LauraMMercer;DiClemente,RalphJ;Monahan,JenniferL
通讯作者：
Monahan,JenniferL

Sexual Risk Among African American Women: Psychological Factors and the Mediating Role of Social Skills.

DOI：
10.1080/01463373.2015.1132241
发表时间：
2016
期刊：
Communication quarterly
影响因子：
1.7
作者：
Curran TM;Monahan JL;Samp JA;Coles VB;DiClemente RJ;Sales J
通讯作者：
Sales J

The association between cigarette smoking, virologic suppression, and CD4+ lymphocyte count in HIV-Infected Russian women.

DOI：
10.1080/09540121.2017.1327645
发表时间：
2017-09
期刊：
AIDS care
影响因子：
1.7
作者：
Brown JL;Winhusen T;DiClemente RJ;Sales JM;Rose ES;Safonova P;Levina O;Belyakov N;Rassokhin VV
通讯作者：
Rassokhin VV

Associations Among Perceived HIV Risk, Behavioral Risk and Interest in PrEP Among Black Women in the Southern US.