Duke CTSI

杜克大学CTSI

• 批准号: 7939162
• 负责人: ROBERT M CALIFF
• 金额: $ 49.82万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7939162
• 关键词: Duke; CTSI

Duke proposes to create a Clinical Translational Science Institute (CTSI). This institute will accomplish four specific aims: 1) To create an institute that will transform how fundamental discoveries are translated into improved medical care by supporting creative translational research teams. The institute will provide leadership and resources for original translational and clinical research, and it will develop and perform studies regarding novel methods and approaches to translational and clinical science. 2) Create an environment in which trainees at all levels, including medical and nursing school students, physical therapists, pharmacologists, house staff, fellows, graduate students, junior faculty and career transition faculty can be trained in translational and clinical research. The training will be built on the principle that a rich clinical and translational research environment will provide Duke trainees with models and opportunities for success. 3) Integrate translational and clinical science by fostering collaboration among Duke's departments, institutes, centers, and schools using human resources supported by modern bioinformatics and a new clinical research unit designed to integrate intensive measurements of biological processes. 4) Develop a community model for understanding how to translate the findings of research from bench to bedside to populations using advanced informatics and health services delivery methods. The Duke CTSI will be founded on three entities, or pillars, including the Duke Translational Research Institute (DTRI), the Duke Clinical Research Institute (DCRI), and the Duke Center for Community Research (DCCR). These three entities will bring together and expand existing programs, and will be designed to emphasize the continuities along the spectrum of research that begins in a basic science laboratory and concludes with novel therapies that change outcomes for individual patients. These three pillars (DCRI, DTRI, and DCCR) will be administratively joined into the new Duke Clinical and Translational Science Institute (Duke CTSI), the core of this application. This new institute will link with other key programs, including the Duke Comprehensive Cancer Center, the Duke University School of Nursing, and the Duke Institute for Genome Sciences and Policy, to create a comprehensive home for clinical and translational researchers. The creation of the CTSI is patricianly relevant to public health as it will create an environment that will foster speedier delivery of new interventions and healthcare practices to the community.

杜克建议建立一个临床转化科学研究所（CTSI）。该研究所将 完成四个具体目标： 1）创建一个将改变基本发现如何改进的研究所 通过支持创意翻译研究团队来提供医疗服务。该研究所将提供 原始翻译和临床研究的领导和资源，它将发展和 进行有关新颖方法和转化和临床科学方法的研究。 2）创造一个环境，包括医学和护理学校在内的各个级别的学员 学生，物理治疗师，药理学家，房屋工作人员，研究员，研究生，初中 教师和职业过渡教师可以接受翻译和临床研究的培训。这 培训将基于以下原则：丰富的临床和翻译研究环境将 为杜克学员提供成功的模型和机会。 3）通过促进杜克部门的合作来整合翻译和临床科学， 使用现代生物信息学支持的人力资源，机构，中心和学校 新的临床研究部门旨在整合生物过程的密集测量。 4）开发一个社区模型，以了解如何转化从中的研究结果 使用先进的信息学和保健服务交付方法的人口床位。 杜克CTSI将建立在包括杜克翻译在内的三个实体或支柱上 研究所（DTRI），杜克临床研究所（DCRI）和杜克大学中心 社区研究（DCCR）。这三个实体将聚集在一起并扩展现有计划， 并将旨在强调沿着基本的研究范围的连续性 科学实验室并以新型疗法的结论，这些疗法改变了个别患者的预后。 这三个支柱（DCRI，DTRI和DCCR）将在行政上加入新的杜克临床 和翻译科学研究所（CTSI），该应用程序的核心。这个新研究所将链接 与其他关键计划，包括杜克大学癌症中心，杜克大学学校 护理和杜克大学基因组科学与政策研究所，为 临床和翻译研究人员。 CTSI的创建与公共卫生具有贵族相关，因为它将创造一个环境 将促进向社区迅速提供新的干预措施和医疗保健实践。