Virtual Activities of Living for Occupational Rehabilitation

职业康复生活虚拟活动

• 批准号: 10382990
• 负责人: Richard J. Adams
• 金额: $ 29.98万
• 依托单位: BARRON ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10382990
• 关键词: 3-Dimensional; Activities of Daily Living; Address; Adherence; Adult; Affect; Articular Range of Motion; Award; Blinded; COVID-19 pandemic; Caring; Cellular Phone; Chronic; Clinical; Cognitive; Complex; Computer Vision Systems; Computer software; Data; Elderly; Environment; Exercise; Facebook; Feedback; Frequencies; Goals; Gold; Hand; Hand functions; Healthcare; Home; Home environment; Immersion; Impairment; Incidence; Individual; Intervention; Interview; Investigation; Manuals; Marketing; Measures; Methods; Modeling; Monitor; Motion; Motor; Motor Skills; Movement; Nervous System Trauma; Occupational; Occupational Therapist; Occupational Therapy; Occupations; Participant; Patients; Performance; Phase; Physicians; Pilot Projects; Process; Provider; Public Health; Questionnaires; Randomized Controlled Trials; Recovery of Function; Rehabilitation therapy; Research; Running; Safety; Small Business Innovation Research Grant; Software Engineering; Stroke; System; Technology; Testing; Time; Universities; Upper Extremity; User-Computer Interface; Video Games; Wolves; Work; base; cognitive function; cognitive skill; cost; deep learning; design; digital; dosage; evidence base; exercise program; exergame; experience; functional independence; functional status; improved; improved outcome; individual patient; innovation; instrument; instrumental activity of daily living; mental imagery; motor recovery; neural network; patient safety; programs; prototype; psychologic; remote monitoring; repetitive task practice; satisfaction; sensor; standard measure; stroke outcome; stroke patient; stroke rehabilitation; stroke therapy; telehealth; underserved area; usability; virtual; virtual assessment; virtual library; virtual reality; virtual reality environment; virtual reality headset; virtual reality sickness; virtual reality system; virtual world; web app; wireless

PROJECT SUMMARY/ABSTRACT Introduction: The Virtual Activities of Living for Occupational Rehabilitation (VALOR) SBIR program will support telehealth delivery and remote monitoring of upper extremity (UE) stroke rehabilitation through the practice of virtual activities of daily living (ADLs) and instrumental ADLs (IADLs). The VALOR system marries ground- breaking untethered virtual reality (VR) headset technology and deep learning runtime 3D motion tracking with an existing suite of digital ADL/IADL content to enable functional, repetitive task practice at home with telehealth support. A key technological breakthrough is markerless tracking that employs cameras built into a low-cost VR headset, enabling patients to manually engage in virtual occupations using their affected UE. The VALOR Phase I program pursues two primary investigational objectives through a pilot study conducted by Duke University: (1) assess the usability and technology acceptance of immersive VR ADL/IADL practice for UE therapy by older adult stroke patients; and (2) establish the validity of immersive virtual ADL/IADL practice for tracking a patient's UE motor status to enable telehealth feedback and monitoring. Technical work in Phase I includes integration of a runtime neural network for real-time UE tracking with an existing suite of virtual ADLs/IADLs (originally developed for a non-immersive, PC-based system using the Kinect) to support immersive VR using a low cost standalone, untethered headset (no PC, no monitor, and no additional sensors required). Problem to be addressed: The COVID-19 pandemic exposed a critical lack of options for delivering an evidence-based UE intervention via telehealth. Innovative solutions are needed to enable patients to safely participate from home in a therapist-monitored therapy program. Approximately 50% of the >795,000 individuals hospitalized due to stroke each year in the U.S. suffer from chronic deficits in UE function [1], [2]. Existing clinical therapy systems for immersive VR are too expensive, complex, and/or bulky for use in patients' homes. Game consoles, exergames, or slipshod, non-evidence-based adaptations of VR technology do not address the integrated motor and cognitive skills required to achieve functional independence in daily living activities. Long-Term Goal: Improved outcomes and functional independence for patients with neurological injury. Phase I Summary: Phase I will produce a prototype VALOR system that consists of a mobile software application that runs on an Oculus Quest 2 untethered (i.e., wireless) VR headset. At least 3 immersive ADL/IADL activities will be fully integrated and tested, leveraging an existing library of virtual world assets from a non- immersive clinical VR system. A pilot study conducted by Duke University with stroke patients will demonstrate usability and technology acceptance, and investigate the hypothesis that metrics captured during immersive ADL/IADL practice will have high criterion validity with respect to gold standard measures of UE function. Commercial Opportunity: The VALOR product is poised to rapidly transition through well-established marketing and distribution channels to meet a critical need for evidence-based telehealth occupational therapy.

项目概要/摘要 简介：职业康复生活虚拟活动 (VALOR) SBIR 计划将支持 通过以下实践对上肢（UE）中风康复进行远程医疗服务和远程监测 虚拟日常生活活动 (ADL) 和工具性 ADL (IADL)。 VALOR 系统与地面结合 突破不受束缚的虚拟现实 (VR) 耳机技术和深度学习运行时 3D 运动跟踪 现有的数字 ADL/IADL 内容套件，可通过远程医疗在家实现功能性、重复性任务练习 支持。一项关键的技术突破是采用低成本 VR 内置摄像头的无标记跟踪 耳机，使患者能够使用受影响的 UE 手动参与虚拟工作。 VALOR 第一阶段计划通过由以下机构进行的试点研究来追求两个主要研究目标： 杜克大学：(1) 评估 UE 沉浸式 VR ADL/IADL 实践的可用性和技术接受度 老年中风患者的治疗； (2) 建立沉浸式虚拟 ADL/IADL 练习的有效性 跟踪患者的 UE 运动状态以实现远程医疗反馈和监控。一期技术工作 包括用于实时 UE 跟踪的运行时神经网络与现有虚拟套件的集成 ADL/IADL（最初是为使用 Kinect 的非沉浸式、基于 PC 的系统开发的）以支持沉浸式体验 VR 使用低成本独立、不受束缚的耳机（无需 PC、无需显示器，也不需要额外的传感器）。 需要解决的问题：COVID-19 大流行暴露了提供医疗服务的选项严重缺乏 通过远程医疗进行基于证据的 UE 干预。需要创新的解决方案来使患者能够安全地 在家参加治疗师监控的治疗计划。 >795,000 人中约 50% 在美国，每年因中风住院的患者都患有 UE 功能的慢性缺陷 [1], [2]。现有临床 沉浸式 VR 治疗系统过于昂贵、复杂和/或笨重，不适合在患者家中使用。游戏 游戏机、运动游戏或马虎的、基于非证据的 VR 技术改编都不能解决这个问题 在日常生活活动中实现功能独立所需的综合运动和认知技能。 长期目标：改善神经损伤患者的预后和功能独立性。 第一阶段总结：第一阶段将生产一个由移动软件组成的原型 VALOR 系统 在 Oculus Quest 2 无线（即无线）VR 耳机上运行的应用程序。至少 3 个沉浸式 ADL/IADL 活动将得到充分集成和测试，利用非虚拟世界资产的现有库。 沉浸式临床VR系统。杜克大学对中风患者进行的一项试点研究将证明 可用性和技术接受度，并研究沉浸式过程中捕获的指标的假设 ADL/IADL 实践对于 UE 功能的黄金标准测量具有很高的标准有效性。 商业机会：VALOR 产品准备通过成熟的市场快速转型 营销和分销渠道，以满足基于证据的远程医疗职业治疗的迫切需求。