Glove Rehabilitation Application for Stroke Patients (GRASP)

中风患者手套康复应用 (GRASP)

• 批准号: 9254255
• 负责人: Richard J. Adams
• 金额: $ 22.5万
• 依托单位: BARRON ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-20 至 2018-05-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9254255
• 关键词: Accelerometer; Activities of Daily Living; Address; Adherence; American; Area; Award; Brain Injuries; Calibration; Case Study; Chronic; Clinical; Computer software; Control Groups; Cost Control; Development; Discipline of Nursing; Feedback; Fingers; Frequencies; Generations; Goals; Hand; Hand functions; Health; Healthcare; Home Health Agency; Home environment; Hospitals; Individual; Legal patent; Manuals; Marketing; Measures; Monitor; Motion; Motivation; Motor; Movement; Orthotic Devices; Outcome; Outpatients; Patients; Performance; Personal Computers; Phase; Pilot Projects; Positioning Attribute; Provider; Public Health; Randomized Controlled Trials; Recovery of Function; Rehabilitation therapy; Research; Services; Small Business Innovation Research Grant; Space Suits; Stroke; System; Technology; Time; Travel; United States National Aeronautics and Space Administration; Universities; User-Computer Interface; Video Games; Virginia; Work; Wrist; abstracting; arm function; base; cost; design; dexterity; dosage; efficacy trial; evidence base; experience; functional outcomes; functional status; grasp; hand rehabilitation; hand therapy; improved; improved outcome; individual patient; innovation; instrument; mental imagery; motor recovery; programs; prototype; psychologic; satisfaction; sensor; standard care; stroke therapy; tool; usability; virtual; virtual reality

PROJECT SUMMARY/ABSTRACT Introduction: The Glove Rehabilitation Application for Stroke Patients (GRASP) Fast-Track SBIR program will promote recovery of hand function following stroke through an instrumented orthosis that enables functional practice of manual tasks in fun and engaging activities within a virtual environment. The effort combines patented sensor glove technology developed under the NASA space suit program with a commercial hand orthosis and modern game engine technology. GRASP will automatically assess a patient's functional level and adapt the challenge to his/her capabilities. In each session, the system will automatically produce valid metrics of hand function, providing both patients and providers with immediate feedback on status and progress. The low-cost product will support independent home use as well as serve as part of a therapist- guided in-patient, skilled nursing, outpatient, home health, or teletherapy rehabilitation program. Problem to be addressed: GRASP addresses the critical challenges of: (1) improving outcomes in hand therapy through task-directed practice and mental imagery that promote functional recovery; (2) enabling increased dosage, intensity, and duration through independent home use and teletherapy; (3) minimizing total cost of rehabilitation by reducing patient/therapist travel; and (4) improving services in underserved areas. Long-Term Goal: Improved outcomes and functional independence for patients with acquired brain injury. Phase I Summary: Phase I of the Fast-Track will produce a prototype system that consists of a sensor package and software application that permits a commercial glove orthosis to be used for practice of virtual activities of daily living (ADLs) in a compelling virtual world. A pilot study conducted by the University of Virginia (UVa), UVa HealthSouth Rehabilitation Hospital, and Continuum Home Health will investigate the primary Phase I hypothesis, which states that GRASP-generated metrics correlate significantly with accepted measures of hand function. Two Phase I case studies led by home health therapists will explore usability in the home environment and serve as pathfinders for Phase II efficacy trials. Phase II Summary: Phase II of the Fast-Track will include: (1) development of a commercial system; (2) extension of the range of hand therapy activities and expansion of virtual environments to provide an engaging and motivating experience across 8 weeks of treatment; (3) provider tools for prescribing and monitoring status/progress; and (4) teletherapy interfaces. A Phase II efficacy study will investigate improvement in standardized assessment scores and adherence for GRASP at-home therapy vs. standard care. Randomized, controlled trials will be led by UVa in partnership with HealthSouth and Continuum Home Health. Commercial Opportunity: Approximately 50% of the 800,000 individuals hospitalized due to stroke each year in the U.S. suffer from chronic deficits in hand and/or arm function [1], [2]. GRASP is poised to rapidly transition evidence-based research to market by leveraging an existing brand with well-defined distribution channels.

项目概要/摘要 简介：中风患者手套康复应用 (GRASP) 快速通道 SBIR 计划将 通过仪器矫形器促进中风后手部功能的恢复，该矫形器可实现功能性 在虚拟环境中进行有趣且引人入胜的活动中练习手动任务。努力结合 在 NASA 太空服计划下用商业手开发的专利传感器手套技术 矫形器和现代游戏引擎技术。 GRASP 将自动评估患者的功能水平 并根据他/她的能力调整挑战。在每个会话中，系统都会自动产生有效的 手功能指标，为患者和提供者提供有关状态和功能的即时反馈 进步。这款低成本产品将支持独立家庭使用，并作为治疗师的一部分- 指导住院、熟练护理、门诊、家庭健康或远程治疗康复计划。 要解决的问题：GRASP 解决以下关键挑战：(1) 改善现有成果 通过任务导向的练习和心理想象来促进功能恢复的治疗； (2) 启用 通过独立家庭使用和远程治疗增加剂量、强度和持续时间； (3) 最小化总数 通过减少患者/治疗师的旅行来降低康复成本； (4) 改善服务欠缺地区的服务。 长期目标：改善获得性脑损伤患者的预后和功能独立性。 第一阶段摘要：快速通道的第一阶段将生产一个由传感器组成的原型系统 软件包和软件应用程序允许使用商业手套矫形器进行虚拟练习 在引人入胜的虚拟世界中进行日常生活活动 (ADL)。弗吉尼亚大学进行的一项试点研究 (UVa)、UVa HealthSouth 康复医院和 Continuum Home Health 将调查主要 第一阶段假设，该假设指出 GRASP 生成的指标与公认的指标显着相关 手部功能的测量。由家庭健康治疗师领导的两个第一阶段案例研究将探讨以下方面的可用性： 家庭环境并作为 II 期疗效试验的探路者。 第二阶段总结：快速通道第二阶段将包括：（1）商业系统的开发； (2) 扩展手部治疗活动的范围并扩展虚拟环境，以提供引人入胜的体验 以及 8 周治疗过程中的激励体验； (3) 提供处方和监测的工具 状态/进展； (4) 远程治疗接口。 II 期疗效研究将调查改善 GRASP 家庭治疗与标准护理的标准化评估分数和依从性。随机化， 对照试验将由弗吉尼亚大学与 HealthSouth 和 Continuum Home Health 合作领导。 商业机会：每年因中风住院的 80 万人中约有 50% 在美国，患有手和/或手臂功能慢性缺陷的人 [1], [2]。 GRASP 准备快速转型 通过利用具有明确分销渠道的现有品牌进行基于证据的研究，将其推向市场。