Core A: Administrative Core

核心A：行政核心

基本信息

批准号：
10473807
负责人：
Henry L Paulson
金额：
$ 50.11万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-01 至 2026-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10473807
关键词：
Address Advocacy Age Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Awareness Black race Brain imaging Clinical Collaborations Communities Counseling Dementia Development Disclosure Education and Outreach Educational Activities Ensure Funding Goals Health Professional Human Resources Leadership Link Manuscripts Medical Michigan Mission Nerve Degeneration Neurologic Neuropsychology Ohio Patient Recruitments Positioning Attribute Productivity Reproducibility Research Research Activity Research Personnel Research Training Resources Risk Factors Sampling Strategic Planning Talents Training United States National Institutes of Health Universities Work age related brain dysfunction clinical care cognitive change cohesion data exchange education research human subject imaging biomarker innovation meetings next generation outreach programs racial and ethnic disparities research study skills sound success supportive environment synergism training opportunity

项目摘要

ABSTRACT – CORE A: ADMINISTRATIVE CORE The key functions of the Administrative Core (AC) are to: a) maximize the local, statewide and national impact of initiatives developed and implemented by the Michigan ADRC; b) enhance collaborations across the three partner universities comprising the consortium (University of Michigan, Wayne State University and Michigan State University) and with the NACC, NCRAD and outside investigators; c) provide sound oversight for fiscal and personnel matters; and d) ensure rigor, integrity and transparency in the research and activities supported by the center. The AC’s stable leadership ensures that the various research, training and outreach initiatives managed by the Cores will maintain synergy and connection to the Michigan ADRC’s central theme, which is to identify, understand and modulate the myriad non-β-amyloid factors that contribute to brain dysfunction and neurodegeneration in AD and related dementias. The AC will ensure a broadly supportive environment for all investigators, but particularly for junior investigators, with the goal of nurturing a diverse group of next- generation leaders. To have maximal effect as an ADRC, the AC will work closely with other centers and programs across the consortium that are engaged in age-related research, including the six NIA-funded centers that together comprise the UMAging Initiative. In six aims the AC will: 1) Leverage expert dementia resources and skills focused in each Core; 2) Maintain cohesive interplay across the Cores; 3) Sustain existing and build new local and regional partnerships; 4) Sustain existing and build further national partnerships; 5) Promote efforts to address racial and ethnic disparities in ADRD; and 6) Develop next-generation leaders through diverse research and training opportunities. In its first cycle as an NIH-designated ADRC, the Michigan ADRC met its milestones due, in part, to a proactive AC that helped build key state-wide partnerships. Benefitting from close links to the many complementary NIA-funded programs on our campuses, the outstanding additional resources of all three universities, and continuing philanthropic success, the Michigan ADRC is well-positioned to further enrich innovative dementia research, outreach, and training efforts, both regionally and nationally.

摘要 – 核心 A：行政核心行政核心 (AC) 的主要职能是： a) 最大限度地发挥地方、司法和国家影响力密歇根 ADRC 制定和实施的举措 b) 加强三者之间的合作；该联盟的合作伙伴大学（密歇根大学、韦恩州立大学和密歇根大学）州立大学）并与 NACC、NCRAD 和外部调查人员合作 c）为财政提供健全的监督；和人事事项；以及 d) 确保所支持的研究和活动的严谨性、完整性和透明度中心的稳定领导确保了各种研究、培训和推广活动的顺利开展。由核心管理的项目将保持与密歇根 ADRC 中心主题的协同作用和联系，即识别、理解和调节导致大脑功能障碍的无数非β-淀粉样蛋白因子 AC 将确保为所有人提供广泛的支持环境。调查员，特别是初级调查员，其目标是培养多样化的下一代—— 为了发挥 ADRC 的最大作用，AC 将与其他中心和机构密切合作。该联盟中从事与年龄相关的研究的项目，包括 NIA 资助的六个项目共同组成 UMAging Initiative 的六个中心将： 1) 利用痴呆症专家。集中于每个核心的资源和技能； 2) 保持核心之间的凝聚力相互作用； 3) 维持现有的建立新的地方和区域伙伴关系； 4) 维持现有的并建立进一步的国家伙伴关系；促进解决 ADRD 中的种族和民族差异；6) 培养下一代领导人；密歇根大学作为 NIH 指定的 ADRC 的第一个周期，通过各种研究和培训机会。 ADRC 实现了其里程碑，部分原因是积极主动的 AC 帮助建立了关键的全州合作伙伴关系。受益于与我们校园内许多由 NIA 资助的补充项目的密切联系，所有三所大学的出色额外资源以及持续的慈善事业成功，密歇根大学 ADRC 处于有利地位，可以进一步丰富创新性痴呆症研究、推广和培训工作，区域和国家层面。