Data Science Core - Center for the Study of Symptom Science, Metabolomics and Multiple Chronic Conditions

数据科学核心 - 症状科学、代谢组学和多种慢性病研究中心

• 批准号: 10456831
• 负责人: VICKI Stover HERTZBERG
• 金额: $ 8.03万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-14 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10456831
• 关键词: Address; Anxiety; Biological; Biological Assay; Clinical Management; Collaborations; Common Data Element; Consultations; Data; Data Analyses; Data Collection; Data Science; Data Science Core; Development; Education; Educational Activities; Future; Goals; Manuscripts; Nurses; Phase; Pilot Projects; Procedures; Quality Control; Questionnaires; Reproducibility; Research; Research Design; Research Personnel; Resource Sharing; Scientist; Secure; Symptoms; System; Visualization; Work; computer infrastructure; data management; design; instrument; metabolomics; microbiome; microbiome analysis; multiple chronic conditions; privacy preservation; programs; quality assurance; skills; symptom science

ABSTRACT The Data Science Core of the Center for the Study of Symptom Science, Metabolomics, and Multiple Chronic Conditions will support the data science needs of the nurse scientist investigators and will enhance the data science skills of current and future nurse scientists. The Core supports the aims of the Center by working with the pilot and other nurse scientist investigators as they develop the research plans for their projects. In particular the core will collaborate on study design and implementation, as well as data collection, management, analysis, and dissemination. The Core provides expertise in the analysis of metabolomics and microbiome data, of particular relevance to the aims of the pilot studies proposed. In addition the core will work with the pilot investigators as they prepare manuscripts and presentation, providing assistance with interpretation and visualization of results. With respect to data management, the Core will work with the pilot project investigators to develop projects within Emory’s REDCap and LabKey systems for managing the clinical, questionnaire, and biological data. In particular, the Core supports standard templates for the instruments proposed for symptom assessment (e.g., PROMIS Anxiety scale). Moreover the Core will implement common data elements for each study. The Core will implement Quality Control and Quality Assurance procedures for data collection and management. Data will be stored securely in order to preserve privacy and confidentiality. The Core has implemented reproducible workflows for metabolomic and microbiome analyses using R, R Markdown, Git, and GitHub, which also assures version control. The Core will also support resource sharing, uploading data to the Emory Dataverse as well as creation of an NCBI BioProject.

抽象的 症状科学、代谢组学和多重疾病研究中心的数据科学核心 慢性病将支持护士科学家研究人员的数据科学需求，并将 提高当前和未来护士科学家的数据科学技能。核心支持以下目标。 该中心通过与试点和其他护士科学家调查员合作开发 特别是，核心将在研究设计和研究计划方面进行合作。 实施以及数据收集、管理、分析和传播。 提供代谢组学和微生物组数据分析方面的专业知识，尤其与 此外，核心人员将与试点研究人员合作。 准备手稿和演示文稿，提供解释和可视化方面的帮助 在数据管理方面，核心将与试点项目研究人员合作，以确保结果。 在埃默里大学的 REDCap 和 LabKey 系统中开发项目来管理临床、 特别是，核心支持问卷和生物数据的标准模板。 建议用于症状评估的工具（例如，PROMIS 焦虑量表）。 核心将实施质量控制和实施每项研究的通用数据元素。 数据收集和管理的质量保证程序数据将安全地存储在。 为了保护隐私和机密性，Core 实施了可重复的工作流程。 使用 R、R Markdown、Git 和 GitHub 进行代谢组学和微生物组分析，这也确保 Core 还将支持资源共享，将数据上传到 Emory Dataverse。 以及创建 NCBI 生物项目。