Florida Regional Coordinating Center for the NINDS Stroke Trials Network

NINDS 中风试验网络佛罗里达地区协调中心

• 批准号: 10868216
• 负责人: JOSE G ROMANO
• 金额: $ 10.95万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-01 至 2023-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10868216
• 关键词: Acute; Address; Agreement; Animal Model; Area; Blood; Blood Vessels; Brain; Caribbean region; Caring; Cerebrovascular Disorders; Clinic; Clinical; Clinical Research; Clinical Trials; Collaborations; DNA; Data Coordinating Center; Degree program; Disparity; Education; Emergency Medicine; Emergency medical service; Endowment; Enrollment; Ensure; Fellowship; Florida; Funding; Future; Genomics; Geography; Goals; Health Sciences; Hispanic Populations; Hospitals; Infrastructure; Institution; Institutional Review Boards; Intervention; Intervention Studies; Memory Loss; Mentors; Mentorship; Minority; Multicenter Studies; National Institute of Neurological Disorders and Stroke; Neurology; Neurosciences; Outcome; Paralysed; Participant; Pediatric Hospitals; Pediatric Neurology; Phase; Population Heterogeneity; Positioning Attribute; Prevention; Private Hospitals; Privatization; Public Hospitals; Puerto Rico; Rare Diseases; Recovery; Registries; Rehabilitation therapy; Research; Research Personnel; Research Project Grants; Residencies; Resources; Science; Scientist; Secondary Prevention; Site; Stroke; Stroke prevention; Structure; Testing; Tissues; Training; Training Programs; Translational Research; United States National Institutes of Health; Universities; Work; Workforce Development; acute stroke; age related; biobank; career; career development; certificate program; clinical translation; community setting; cultural health; demographics; education resources; ethnic diversity; experience; human genomics; improved; medical schools; member; multidisciplinary; neurological rehabilitation; neurosurgery; next generation; novel; participant enrollment; patient population; post stroke; pre-clinical; programs; recruit; skills; stem cells; stroke intervention; stroke model; stroke therapy; stroke trials; success; telerehabilitation; translational scientist; working group

Florida Regional Coordinating Center for the NINDS Stroke Trials Network This proposal outlines the University of Miami's application to remain as the Florida Regional Coordinating Center (RCC) in the Stroke Trials Network (StrokeNet). The goals of the Florida RCC are to: a) provide a robust and efficient infrastructure to implement high-quality research clinical trials that address acute stroke treatment, prevention and recovery; b) leverage the internal and regional resources to enhance the Stroke Trials Network; c) train the next generation of stroke clinical and translational researchers. The Florida RCC encompasses a large network of participating acute stroke, rehabilitation and pediatric hospitals that span across Florida, to ensure robust enrollment of an ethnically diverse population that reflects the changing demographics of the US. Our stroke program has a successful track record of participating in numerous NINDS acute and secondary prevention stroke trials, and is involved in other NIH networks and coordinates multicenter studies. Through our participating sites, extended referral network and multidisciplinary expertise, we will build upon the close partnership with pre-hospital Emergency Services, Emergency Medicine, Vascular Neurosurgery, Interventional Neurology, Neuro-Critical Care, Pediatric Neurology and Neurorehabilitation, as well as on academic-public- private institutional collaborations, to enroll and manage potential study participants. We also have unique resources that we can bring to the network. Integrated collaboration among cutting edge researchers in the areas of preclinical stroke, stem cells, human genomics, biorepository, brain bank, and the Miami CTSI make us uniquely positioned to develop, propose and implement novel translational early phase projects. The large residency and fellowship training programs in Neurosciences, the multidisciplinary educational resources in the institution, and our track record of mentoring clinical researchers, position our center to effectively train stroke researchers in clinical and translational research through a structured mentored program. Over the past funding cycle we have been an outstanding StrokeNet member: we expanded the RCC representation across Florida by adding new outstanding sites, recruited well into StrokeNet trials, were a top performer in regulatory metrics, trained 3 StrokeNet scholars, participated in 3 working groups and committees, submitted new proposals to the Network, and were engaged in all aspects of the program. Therefore, we have the depth and breadth of expertise and resources to successfully function as a RCC in the StrokeNet.

NINDS中风试验网络佛罗里达州区域协调中心 该提案概述了迈阿密大学的申请，以保持佛罗里达地区协调 中风试验网络（Strokenet）中的中心（RCC）。佛罗里达RCC的目标是：a）提供强大的 和有效的基础设施来实施针对急性中风治疗的高质量研究临床试验， 预防和恢复； b）利用内部和区域资源来增强中风试验网络； c）训练下一代中风临床和翻译研究人员。佛罗里达RCC包括 跨越佛罗里达州的大型参与急性中风，康复和儿科医院网络 确保众多种族多样化的人口的强大入学，这反映了美国不断变化的人口统计。 我们的中风计划成功地参与了许多Ninds急性和次要的记录 预防中风试验，并参与其他NIH网络并协调多中心研究。通过我们的 参与网站，扩展的推荐网络和多学科专业知识，我们将在接近 与院前紧急服务，急诊医学，血管神经外科手术，介入的伙伴关系 神经病学，神经关键护理，儿科神经病学和神经康复，以及学术公共 私人机构合作，以注册和管理潜在的研究参与者。我们也有独特的 我们可以带入网络的资源。尖端研究人员之间的综合协作 临床前中风，干细胞，人类基因组学，生物库，脑库和迈阿密CTSI的领域 美国独特地定位，可以开发，提出和实施新型的翻译早期项目。大 神经科学的居住和奖学金培训计划，是多学科教育资源 机构以及我们指导临床研究人员的记录，将我们的中心定位为有效训练中风 通过结构化的指导计划在临床和转化研究方面的研究人员。在过去的资金中 周期我们一直是杰出的拼写成员：我们在佛罗里达州扩大了RCC代表 通过添加新的杰出网站，招募良好进入拼写物试验，是监管指标的表现最佳的人， 经过培训的3名Strokenet学者，参加了3个工作组和委员会，向 网络，并参与该计划的各个方面。因此，我们的深度和广度 专业知识和资源可以成功地充当拼写物中的RCC。