Miami Regional Coordinating Center for NINDS Stroke Trials Network

NINDS 卒中试验网络迈阿密区域协调中心

• 批准号: 8662502
• 负责人: JOSE G ROMANO
• 金额: $ 38.29万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-30 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8662502
• 关键词: Acute; Address; Agreement; Area; Authorship; Blood; Blood Vessels; Brain; Caribbean region; Caring; Cerebrum; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Design; Collaborations; Critical Care; Education; Emergency Medicine; Emergency medical service; Endowment; Enrollment; Ensure; Fellowship; Fellowship Program; Florida; Genomics; Goals; Grant; Hispanics; Hospitals; Human; Institutes; Institution; Institutional Review Boards; Instruction; Intervention; Intervention Studies; Manuscripts; Mentors; Mentorship; Methods; National Institute of Neurological Disorders and Stroke; Neurology; Neurorehabilitation; Neurosciences; Participant; Patients; Pediatric Hospitals; Pediatric Neurology; Phase; Population Heterogeneity; Positioning Attribute; Prevention; Principal Investigator; Public Health; Puerto Rico; Recovery; Registries; Rehabilitation therapy; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Residencies; Resources; Scientist; Secondary Prevention; Site; Stroke; Stroke prevention; Structure; Testing; Tissues; Training; Training Programs; Translational Research; United States National Institutes of Health; Universities; Vascular Diseases; Work; Writing; acute stroke; biobank; data management; demographics; experience; human stem cells; medical schools; metropolitan; multidisciplinary; neurosurgery; next generation; novel; patient population; pre-clinical; programs; public health relevance; repository; research study; response; responsible research conduct; skills; stem cells; telehealth

DESCRIPTION (provided by applicant): This proposal outlines the University of Miami's application to become a Regional Coordinating Center (RCC) in the Stroke Trials Network. The goals of the Miami RCC are to: a) provide a robust and efficient infrastructure to implement high-quality research clinical trials that address acute stroke treatment, prevention and recovery; b) leverage the internal and regional resources to enhance the Stroke Trials Network; c) train the next generation of stroke clinical and translational researchers. The Miami RCC encompasses a large network of participating acute care, rehabilitation and pediatric hospitals that span South Florida, the largest metropolitan area in the Southeast, to ensure robust enrollment of an ethnically diverse, predominantly Hispanic, population that reflects the changing demographics of the US. Our stroke program has a successful track record of participating in numerous NINDS acute and secondary prevention stroke trials, and is involved in other networks (Neuro-NEXT, SPIRP). Through our Comprehensive Stroke Center, extended referral network and multidisciplinary expertise, we will build upon the close partnership with pre-hospital Emergency Services, Emergency Medicine, Vascular Neurosurgery, Interventional Neurology, Neuro-Critical Care, Pediatric Neurology and Neurorehabilitation, as well as on academic-private institutional collaborations, to enroll and manage potential study participants. We also have unique resources that we can bring to the network. Integrated collaboration among cutting edge researchers in the areas of preclinical stroke, stem cells, human genomics, biorepository, brain bank, and the Miami CTSI make us uniquely positioned to develop, propose and implement novel translational early phase projects. The large residency and fellowship training programs in Neurology, the multidisciplinary educational resources in the institution, and our track record of instructing clinical researchers position our center to effectively train strok researchers in clinical and translational research through a structured mentored program. Therefore, we have the depth and breadth of expertise and resources to successfully function as a RCC in the Stroke Trials Network.

描述（由申请人提供）：该提案概述了迈阿密大学在中风试验网络中成为区域协调中心（RCC）的申请。迈阿密RCC的目标是：a）提供强大而有效的基础设施，以实施高质量的研究临床试验，以解决急性中风治疗，预防和恢复； b）利用内部和区域资源来增强中风试验网络； c）训练下一代中风临床和翻译研究人员。迈阿密RCC涵盖了一个庞大的参与急性护理，康复和儿科医院，这些网络跨越了南佛罗里达州南部佛罗里达州，这是东南部最大的大都市地区，以确保反映我们不断变化的我们人口统计学的人口，以确保富有种族多样化的族裔，主要是西班牙裔的人口。我们的中风计划成功地参与了许多NINDS急性和次要预防中风试验，并参与了其他网络（Neuro-Next，Spirp）。通过我们的全面中风中心，扩展的推荐网络和多学科专业知识，我们将与院前紧急服务，急诊医学，血管神经外科手术，介入神经病学，神经临界护理，儿科神经疗法和神经治疗疗法和神经治疗疗法以及在学术机构合作以及参与者的参与者之间建立联系和参与。我们也有独特的资源可以带到网络上。在临床前中风，干细胞，人类基因组学，生物库，脑库和迈阿密CTSI领域的前沿研究人员之间的综合协作使我们在开发，提出和实施新颖的早期早期阶段项目方面独特地定位。神经病学，机构的多学科教育资源的大型居住和奖学金培训计划以及 我们指导临床研究人员将中心定位的记录记录通过结构化的指导计划有效地培训临床和翻译研究中的中风研究人员。因此，我们拥有专业知识和资源的深度和广度，可以成功地充当中风试验网络中的RCC。