Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke Prevention (I-TEST BP/Stroke)

扩展受音乐启发的血压和中风预防策略的创新工具（I-TEST BP/中风）

• 批准号: 10937709
• 负责人: OLIVER CHUKWUJEKWU EZECHI
• 金额: $ 71.66万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-29 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10937709
• 关键词: Innovative; Tools; Expand; Music; Inspired

Expanding evidence-based blood pressure/stroke prevention interventions for youth and their older adult caregivers (parents, grandparents, etc.) is critical to achieving the World Health Organization (WHO) and Nigerian goals for reducing the hypertension and stroke burden. Innovative strategies that engage local communities, link younger and older generations, and decrease health disparities are urgently needed. Music is a positive social determinant of health that is inclusive and can allow people to achieve healthy outcomes. It is also a non-invasive, safe, inexpensive, evidence-based implementation strategy, that can be used to engage youth in intervention design and evaluation tailored to their specific needs and those of their older adult caregivers. The effectiveness of music as an implementation strategy has been documented in various randomized control trials, including blood pressure and stroke prevention interventions. Nigeria also has a rich music culture that can be leveraged to increase uptake of evidence-based BP/stroke interventions. We propose “Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke Prevention (I- TEST BP/Stroke)” to accelerate behavioral BP/stroke campaigns in Nigeria inspired by music. I-TEST- BP/stroke will use participatory crowdsourcing methods to drive BP/stroke prevention among youth/caregiver dyads in Nigeria. Crowdsourcing open calls will allow us to identify locally relevant music-inspired campaigns to increase uptake of BP/stroke prevention. Then, apprenticeships with music and public-health professionals will build capacity for implementing these campaigns using common music elements (i.e., rhythms, beats, lyrics) known to impact cardiovascular health. Our preliminary data from Nigeria demonstrate that youth can develop effective public health interventions using these participatory methods. Our partnership with the Nigerian Institute of Medical Research provides extensive experience in implementation research, participatory methods, and pragmatic trials. Building on this strong foundation, our multi-disciplinary research team proposes a hybrid type II implementation trial with these specific aims: (1) to develop a new, combined, music- inspired BP/stroke campaigns for youth/caregiver dyads using crowdsourcing open calls and apprenticeships; (2) to determine whether the final music-inspired campaign increases uptake of BP/stroke prevention interventions among youth and their caregivers using a stepped-wedge, pragmatic randomized controlled trial (RCT) in 30 geographic areas; (3) to use mixed-methods approach to explore multi-level factors that influence the uptake of the music-inspired strategy. Our primary outcomes will be the uptake of strategy and BP/stroke preventive measures defined here as maintenance of normal BP rates for youth, systolic blood pressure reduction for caregivers, and increase in stroke preparedness knowledge. Secondary outcomes are reach, fidelity, acceptability, and sustainment. Our study is responsive to the strategic priorities of the United States National Institutes of Health, Sound Health, the WHO, the Nigerian Ministry of Health and PAR-22-132.

扩大针对青少年及其老年人的循证血压/中风预防干预措施 照顾者（父母、祖父母等）对于实现世界卫生组织 (WHO) 和 尼日利亚降低高血压和中风负担的目标是吸引当地的创新战略。 迫切需要音乐将社区、年轻一代和老一代联系起来，并减少健康差距。 是健康的积极社会决定因素，具有包容性，可以让人们实现健康的结果。 也是一种非侵入性、安全、廉价、基于证据的实施策略，可用于参与 青年人根据自己及其老年人的具体需求进行干预设计和评估 音乐作为一种实施策略的有效性已在各种文献中得到记录。 尼日利亚也有丰富的随机对照试验，包括血压和中风预防干预措施。 我们可以利用音乐文化来提高循证血压/中风干预措施的采用率。 提出“扩大受音乐启发的血压和中风预防策略的创新工具（I- TEST BP/Stroke）”，以音乐为灵感，加速尼日利亚的行为血压/中风活动。 血压/中风将使用参与式众包方法来推动青少年/护理人员预防血压/中风 尼日利亚的众包公开征集将使我们能够识别当地相关的音乐启发活动。 提高人们对血压/中风预防的认识；然后，接受音乐和公共卫生专业人员的学徒培训。 将建立使用常见音乐元素（即节奏、节拍、 歌词）已知会影响心血管健康，我们来自尼日利亚的初步数据表明，年轻人可以 利用这些参与性方法制定有效的公共卫生干预措施。 尼日利亚医学研究所在实施研究、参与性研究方面提供丰富的经验 建立在这个坚实的基础上，我们的多学科研究团队。 提出了混合型 II 实施试验，其具体目标如下：(1) 开发一种新的、组合的、音乐- 通过众包公开征集和学徒培训，为青少年/护理人员二人组激发了 BP/中风活动的灵感； (2) 确定最终的音乐活动是否会增加人们对血压/中风预防的认识 使用阶梯楔形、务实的随机对照试验对青少年及其照顾者进行干预 （RCT）在30个地理区域；（3）使用混合方法探索多层次的影响因素 我们的主要成果将是策略和血压/中风的采用。 这里定义的预防措施是维持青少年正常血压、收缩压 减少护理人员的工作量，并增加中风准备知识， 我们的研究符合美国的战略重点。 美国国立卫生研究院、Sound Health、世界卫生组织、尼日利亚卫生部和 PAR-22-132。