The Sociostructural Implementation Science Coordination Initiative

社会结构实施科学协调倡议

• 批准号: 10744378
• 负责人: Nanette Dior Benbow
• 金额: $ 120.09万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10744378
• 关键词: AIDS prevention; Achievement; Address; Administrative Supplement; Affect; Behavioral; Caring; Collaborations; Collection; Common Data Element; Communication; Companions; Consultations; Cost Analysis; Data; Development; Disparity; Dissemination and Implementation; Effectiveness; Ensure; Epidemic; Equity; Evidence based intervention; Fostering; Funding; Goals; HIV; HIV disparities; Health; Hearing; Individual; Inequity; Infrastructure; Institution; Intervention; Joints; Journals; Knowledge; Leadership; Learning; Logic; Measurement; Measures; Methodology; Methods; Modeling; Needs Assessment; Newsletter; Outcome; Persons; Policies; Procedures; Research; Research Personnel; Research Priority; Research Project Grants; Resources; Risk; Science; Services; Site; Structure; System; Taxonomy; Testing; Training; United States National Institutes of Health; Viral; Walking; care outcomes; career; cost; dashboard; data harmonization; dissemination science; effectiveness outcome; evidence base; experience; health equity; health inequalities; implementation cost; implementation determinants; implementation measures; implementation outcomes; implementation research; implementation science; implementation strategy; implementation/effectiveness; improved; investigator training; meetings; pre-exposure prophylaxis; prevent; public database; public health research; scale up; service delivery; shared decision making; social determinants; social health determinants; social structure; structural health determinants; symposium; systematic review; tool; transmission process; virtual; web site

We have the biomedical tools necessary to prevent HIV and improve the health of people living with HIV, yet achievement of the Ending the HIV Epidemic goals requires sociostructural interventions that address social determinants of health that contribute to inequities. Evidence-based sociostructural interventions exist that have a direct impact on PrEP, care-related, and viral suppression outcomes, yet they have been much less studied than individual-level interventions and their implementation poses unique methodological and institutional challenges. Determining how sociostructural interventions can reduce health inequities, including implications for implementation and sustainment, is an urgent public health research priority. The Sociostructural Implementation Science Coordination Initiative (SISCI) hub will bring the best of Dissemination and Implementation (D&I) Science to collaborate with the Companion R01s to coordinate data harmonization, foster opportunities for cross-site learning, and coordinate research, capacity building, and dissemination efforts. We will grow the capacity of both researchers and implementers to apply D&I models and methods for developing, testing, and implementing sociostructural interventions. SISCI investigators and consultative team are nationally recognized experts in HIV D&I science and have a strong record of coordinating HIV D&I projects and providing tools and training to the field. The SISCI aims to (1) Assist the companion RO1s through collaboration, knowledge sharing, and expert consultation on D&I science and social determinants of health models and methods. We will coordinate in person and virtual communications between companion R01s and provide tailored methodological support to the projects based on collective needs and opportunities. (2) Integrate implementation and effectiveness data across R01 studies to collect cross-project data and perform integrated analyses. Using shared decision making, we will identify common data elements (CDEs) for collections across projects and plan for integrated analyses. We will deploy data coordination infrastructure to collect cross-project data and perform integrated analyses—whenever possible obtaining administrative data to allow new generalizable knowledge beyond what individual projects have studied. We will disseminate findings on implementation determinants and strategies using our popular HIV implementation science website and newsletter, conference presentations, and a special journal issue of Companion R01 and other sociostructural project findings. (3) Advance the field of sociostructural interventions to reduce HIV disparities by developing and offering a combined D&I science and sociostructural training tailored to early career investigators and implementation partners. We will further grow the capacity of the field by conducting a scoping review to build a compendium of promising and proven implementation strategies for sociostructural interventions. We will support the dissemination of implementation strategies identified in the Companion R01 projects by creation and dissemination of training materials and policy briefs.

我们拥有预防艾滋病毒和改善艾滋病毒感染者健康所需的生物医学工具，但 实现终结艾滋病毒流行目标需要采取社会结构干预措施来解决社会问题 存在导致不平等的健康决定因素。 对 PrEP、护理相关和病毒抑制结果有直接影响，但影响要小得多 研究比个人层面的干预措施及其实施提出了独特的方法论和 确定社会结构干预措施如何减少健康不平等，包括 对实施和维持的影响是公共卫生研究的一个紧迫的优先事项。 社会结构实施科学协调倡议（SISCI）中心将带来最好的传播 和实施 (D&I) 科学与 Companion R01 合作协调数据协调， 促进跨地点学习的机会，协调研究、能力建设和传播 我们将加强研究人员和实施者的能力努力，将 D&I 模型和方法应用于 开发、测试和实施社会结构干预措施。 是全国公认的艾滋病毒 D&I 科学专家，并且在协调艾滋病毒 D&I 方面拥有良好的记录 SISCI 旨在 (1) 协助同伴 RO1 通过。 关于 D&I 科学和健康社会决定因素的合作、知识共享和专家咨询 我们将协调同伴 R01 和 R01 之间的面对面和虚拟通信。 (2) 根据集体需求和机会为项目提供量身定制的方法支持。 整合 R01 研究中的实施和有效性数据，以收集跨项目数据并执行 通过综合分析，我们将确定通用数据元素（CDE）。 我们将部署数据协调基础设施来进行跨项目的收集和计划。 收集跨项目数据并执行综合分析——只要有可能就获取管理数据 允许超出单个项目研究范围的新的通用知识我们将传播研究结果。 使用我们流行的艾滋病毒实施科学网站了解实施决定因素和策略，以及 Companion R01 和其他社会结构的时事通讯、会议演示和特刊 (3) 推进社会结构干预领域，通过发展减少艾滋病毒差异。 并提供针对早期职业调查员和社会结构的综合 D&I 科学和社会结构培训 我们将通过开展范围审查来进一步增强该领域的能力，以建立一个 我们将编制一份有前途且行之有效的社会结构干预实施战略概要。 通过创建支持传播 Companion R01 项目中确定的实施策略 传播培训材料和政策简报。