Predoctoral Training in Cross-disciplinary Molecular and Cellular Biology

跨学科分子和细胞生物学博士前培训

• 批准号: 10620263
• 负责人: Paul Garrity
• 金额: $ 63.66万
• 依托单位: BRANDEIS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10620263
• 关键词: Molecular and Cellular Biology; Training; pre-doctoral

Project Summary/Abstract The goals of this training program entitled “Predoctoral Training in Cross-disciplinary Molecular and Cellular Biology” (CMCB) at Brandeis University are to produce rigorous, quantitative scientists with expertise in multiple disciplines, to provide trainees with the skills needed to succeed in diverse science-related careers, and to help trainees explore and pursue their career interests in an informed manner. This new program combines the complementary strengths of two prior Brandeis T32 programs: “Genetic and Biochemical Mechanisms of Regulation, T32GM007122”, expiring after >40 years of NIGMS support, and “Quantitative Biology, T32EB009419”, expiring after 10 years of NIBIB support. While both training programs had strong track records of student research productivity and career outcomes, we significantly rethought and revised core elements of training (based on student and faculty feedback) to better prepare students for a future in which interdisciplinary research is increasingly crucial. Innovations include: (1) increased quantitative training, through courses and an annual workshop, (2) revising the timing and goal of the qualifying exam, both to improve the training value and to better serve students from diverse scientific and personal backgrounds, (3) earlier implementation of Individual Development Plans and Thesis Committee Meetings to accelerate trainee career development and research progress, (4) introducing a secondary research advisor in a complementary discipline to facilitate interdisciplinary training, (5) a two week professional Externship in Year 4+, (6) new program self-assessment mechanisms, including semi-annual trainee feedback and the creation of an External Advisory Committee, and (7) formal training in and oversight of mentoring for all training faculty. Trainee appointments will be made at the end of Year 1, after students have completed one year of coursework, four 9- week laboratory rotations, and chosen a lab. In Year 2, trainees serve as teaching assistants for one course per semester, take a Proseminar course to help them craft their thesis research plan and defend it at their qualifying exam (end of Year 2), and to develop a career Individual Development Plan (IDP). In Year 3+, trainees take a final elective and focus on their research. They present their work at annual Departmental talks, have annual Thesis Committee Meetings focused on career planning and research progress. In Year 4+, they engage in a two-week career Externship and serve as mentors at the annual Quantitative Analysis workshop. Program outcomes and success will be measured by: (1) sustained research impact (reflected in trainee publications), (2) development of independent scientific thinking and communication (assessed through thesis proposals, annual Departmental talks and Thesis Committee Meetings), (3) active trainee engagement in their own career development (reflected in annual IDPs, discussions at Thesis Committee Meetings, and the new Externship program), and (4) trainee placement and long-term success in science-related careers. There are 29 CMCB training faculty, and 12 slots are requested (~6 trainees/year, with trainees supported in Years 2 and 3).

项目概要/摘要 本次培训项目的目标是“跨学科分子和细胞博士前培训” 布兰迪斯大学的“生物学”（CMCB）旨在培养在多个领域具有专业知识的严谨的定量科学家 学科，为学员提供在各种与科学相关的职业中取得成功所需的技能，并帮助 这个新计划结合了学员以知情的方式探索和追求他们的职业兴趣。 之前两个 Brandeis T32 项目的优势互补：“遗传和生化机制 法规，T32GM007122”，在 NIGMS 支持超过 40 年后到期，以及“定量生物学， T32EB009419”，在 NIBIB 支持 10 年后到期，尽管这两个培训项目都有很强的跟踪能力。 学生研究生产力和职业成果的记录，我们显着重新思考和修订了核心 培训要素（基于学生和教师的反馈），以便更好地为学生的未来做好准备 跨学科研究变得越来越重要，包括：（1）增加定量训练， 通过课程和年度研讨会，(2) 修改资格考试的时间和目标，以 提高培训价值并更好地服务来自不同科学和个人背景的学生，(3) 尽早实施个人发展计划和论文委员会会议以加速学员的发展 职业发展和研究进展，（4）在补充中引入二级研究顾问 促进跨学科培训的纪律，（5）4年级以上为期两周的专业实习，（6）新 计划自我评估机制，包括半年一次的学员反馈和建立外部 咨询委员会，以及 (7) 对所有培训人员进行正式培训和指导监督。 预约将在第一年结束时进行，学生完成一年的课程后，四个 9- 每周实验室轮换，并选择一个实验室 在第二年，学员担任每门课程的助教。 学期，参加 Proseminar 课程，帮助他们制定论文研究计划并在资格赛中进行答辩 考试（第 2 年末），并制定职业个人发展计划 (IDP) 在第 3 年以上，学员参加考试。 他们在年度部门演讲中展示他们的工作，并进行年度研究。 论文委员会会议的重点是职业规划和研究进展。在四年级以上，他们参与了一项研究。 为期两周的职业实习，并在年度定量分析研讨会上担任导师。 结果和成功将通过以下因素来衡量：(1) 持续的研究影响（反映在受训者出版物中）， (2) 独立科学思维和交流的发展（通过论文提案评估， 年度部门会谈和论文委员会会议），（3）学员积极参与自己的职业生涯 发展（反映在年度国内流离失所者、论文委员会会议的讨论以及新的外部实习中） 计划），以及（4）实习生安置和科学相关职业的长期成功共有 29 个 CMCB。 培训教师，并请求 12 个名额（每年约 6 名受训人员，在第 2 年和第 3 年为受训人员提供支持）。