Dynamic Personalized Feedback for Young Adults with a History of Alcohol-Induced Blackout

为有酗酒史的年轻人提供动态个性化反馈

• 批准号: 10620609
• 负责人: Mary Elizabeth Miller
• 金额: $ 21.9万
• 依托单位: UNIVERSITY OF MISSOURI-COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10620609
• 关键词: Age; Alcohol abuse; Alcohol consumption; Alcoholic beverage heavy drinker; Alcohols; Awareness; Behavior; Blood alcohol level measurement; Communities; Costs and Benefits; Data; Economic Burden; Emergency department visit; Evaluation; Event; Feedback; Female; Frequencies; Goals; Health; Health behavior; Heavy Drinking; Incidence; Individual; Injury; Intervention; Language; Link; Mediator; Medical Care Costs; Memory Loss; Moods; Motivation; National Institute on Alcohol Abuse and Alcoholism; Outcome; Participant; Pattern; Perception; Pharmaceutical Preparations; Phase; Randomized; Randomized, Controlled Trials; Reaction; Recording of previous events; Reporting; Research; Sampling; Self Efficacy; Severities; Sleep; Speed; Strategic Planning; Testing; Treatment Efficacy; Variant; Woman; acceptability and feasibility; alcohol consequences; alcohol intervention; alcohol related consequences; alcohol related problem; alcohol use disorder; brief alcohol intervention; brief intervention; clinical practice; cost; depressive symptoms; design; deter alcohol use; drinking; drinking behavior; efficacy evaluation; efficacy testing; experience; feasibility testing; follow-up; group intervention; heavy drinking young adult; high intensity drinking; high risk; high risk drinking; innovation; interest; intervention cost; intervention participants; intervention refinement; men; mortality; novel; pilot test; post intervention; preventive intervention; primary outcome; prospective; prototype; public health relevance; randomized trial; recruit; response; revictimization; secondary outcome; sexual coercion; social; young adult

PROJECT SUMMARY / ABSTRACT Approximately 50% of young adults who drink alcohol experience alcohol-induced “blackouts,” defined as permanent (en bloc) or temporary (fragmentary) memory loss for events that occurred while they are drinking. This experience of alcohol-induced blackout is associated prospectively with alcohol-related harm, including emergency room visits and sexual coercion, with medical care costs exceeding $469,000 per year. While young adults who have recently experienced a blackout report less favorable evaluations of drinking events and increased motivation to decrease their drinking, they do not actually change their drinking behavior as a result of the blackout alone. Collectively, these data suggest that blackouts may serve as an opportunity for intervention, after which young adults are more likely to respond to alcohol feedback. This R34 aims to develop an intervention tailored to individuals who experience blackouts. The research team developed a dynamic personalized feedback intervention for young adults with a history of blackout. In the first phase of this research (Aim 1 user testing), 15-20 young adults with a history of blackout will provide their perspectives on the proposed content, layout, and language of the intervention. In the second phase of the project (Aim 1 pilot testing), 15 young adults with a history of blackout will pilot the intervention and then provide feedback on their experience with and reactions to delivery. In the final phase (Aim 2 preliminary efficacy testing), 162 young adults (50% female, ≥50% non-college) who report a history of blackout will be randomly assigned to receive the intervention (n=81) or assessment only (n=81). Outcomes will be assessed immediately post-intervention and at 3-month follow-up. Primary outcomes include feasibility (recruitment/retention) and acceptability of the intervention, frequency of high-intensity drinking, peak blood alcohol concentration (BAC), frequency of blackouts, and alcohol-related consequences. Secondary outcomes include incidence of sexual coercion or emergency room visits, perceived likelihood and aversiveness of blackouts, cost/benefits of alcohol use, and self-efficacy of avoid blackouts. Results will inform an R01 randomized trial examining the efficacy and mediators/moderators of the intervention in a larger sample of heavy-drinking young adults. This study will provide initial evidence that blackouts are a feasible and motivating target for brief alcohol interventions.

项目摘要 /摘要 大约50％的饮酒年轻人经历了酒精引起的“停电”，定义为 饮酒期间发生的事件的永久性（En Bloc）或临时（碎片）记忆丧失。 酒精引起的停电经验前景与酒精相关的伤害有关，包括 急诊室就诊和性胁迫，医疗费用超过每年469,000美元。尽管 最近经历过停电报告的年轻人对饮酒活动的评估不佳 并增加了减少饮酒的动力，他们实际上并没有改变自己的饮酒行为 仅停电的结果。总的来说，这些数据表明停电可能是 干预措施，之后，年轻人更有可能对酒精反馈做出反应。 R34旨在发展 针对经历停电的人量身定制的干预措施。研究小组开发了动态 具有停电病史的年轻人的个性化反馈干预。在第一阶段 研究（AIM 1用户测试），有15-20名有停电病史的年轻人将提供他们对 干预的拟议内容，布局和语言。在项目的第二阶段（AIM 1飞行员 测试），15名有停电病史的年轻人将进行干预，然后提供反馈 经验和对交付的反应。在最后阶段（AIM 2初步有效性测试），162年 成人（50％女性，≥50％的非大学）报告停电病史将随机分配接受 干预（n = 81）或仅评估（n = 81）。干预后将立即评估结果 并在3个月的随访中。主要结果包括可行性（招聘/保留）和可接受性 干预，高强度饮酒的频率，峰值血液酒精浓度（BAC），频率 停电和与酒精有关的后果。次要结果包括性胁迫的发生率或 急诊室就诊，可能性和厌恶性停电，饮酒的成本/收益以及 避免停电的自我效能。结果将告知R01随机试验，以检查效率和 干预的调解人/主持人在较大的饮料年轻人样本中进行干预。这项研究会 提供最初的证据，表明停电是短暂酒精干预的可行且激励的目标。