Equipment items to enhance operations at the BioCAT Facility at the Advanced Photon Source

用于增强先进光子源 BioCAT 设施运营的设备项目

• 批准号: 10899388
• 负责人: THOMAS C IRVING
• 金额: $ 36.87万
• 依托单位: ILLINOIS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-02-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10899388
• 关键词: Administrative Supplement; Advisory Committees; Aging; Amyloid; Biological; Biology; Biophysics; Biotechnology; Charge; Collaborations; Communities; Complex; Computer software; Connective Tissue; Data; Data Analyses; Dedications; Development; Drops; Ensure; Equilibrium; Equipment; Fiber; Field Flow Fractionation; Fluorescence Microscopy; Funding; Grant; Illinois; Individual; Infrastructure; Laboratories; Leadership; Ligands; Maintenance; Modification; Molecular; Molecular Biology; Motor; Muscle; National Center for Research Resources; National Institute of General Medical Sciences; Nucleic Acid Folding; Nucleic Acids; Parents; Persons; Photons; Physics; Policies; Principal Investigator; Proteins; Publications; Recruitment Activity; Research; Research Personnel; Research Project Grants; Research Technics; Resources; Sampling; Schedule; Science; Shapes; Source; Spectrophotometry; Structure; Students; Synchrotrons; System; Technology; Time; Training; Training Activity; United States National Institutes of Health; Visit; beamline; biological systems; equipment acquisition; experience; fibrous protein; hexapod; improved; instrumentation; interest; lens; macromolecule; nano; operation; outreach; professor; repaired; structural biology; synchrotron radiation; tool; training opportunity

The purpose of this administrative supplement request is to acquire “Equipment items to enhance operations at the BioCAT Facility at the Advanced Photon Source”. These items were identified as required to meet unmet needs by our users that were not anticipated in the parent P30 proposal. These include a fluorescence microscopy system, a Wyatt Eclipse system for Flow Field Fractionation, a Newport Hexapod motors for Compound Refractive Lenses and a Nanodrop OneC Microvolume UV-Vis Spectrophotometer.

该行政补充请求的目的是获取“增强运营的设备项目” 先进光子源的 BioCAT 设施”。这些项目被确定为满足未满足的要求。 我们的用户的需求在父 P30 提案中没有预料到，其中包括荧光。 显微镜系统、用于流场分离的 Wyatt Eclipse 系统、用于流场分离的 Newport 六足电机 复合折射镜片和 Nanodrop OneC 微量紫外-可见分光光度计。

项目成果

BioXTAS RAW 2: new developments for a free open-source program for small-angle scattering data reduction and analysis.

BioXTAS RAW 2：用于小角度散射数据缩减和分析的免费开源程序的新开发。

• DOI: 10.1107/s1600576723011019
• 发表时间: 2024
• 期刊: Journal of applied crystallography
• 影响因子: 6.1
• 作者: Hopkins,JesseB

Cardiac myosin filaments are directly regulated by calcium.

• DOI: 10.1085/jgp.202213213
• 发表时间: 2022-12-05
• 期刊: JOURNAL OF GENERAL PHYSIOLOGY
• 影响因子: 3.8
• 作者: Ma, Weikang;Nag, Suman;Gong, Henry;Qi, Lin;Irving, Thomas C.
• 通讯作者: Irving, Thomas C.

EMD-57033 Augments the Contractility in Porcine Myocardium by Promoting the Activation of Myosin in Thick Filaments.

• DOI: 10.3390/ijms232314517
• 发表时间: 2022-11-22
• 期刊: International journal of molecular sciences
• 影响因子: 5.6

Structural and functional studies reveal the molecular basis of substrate promiscuity of a glycosyltransferase originating from a major agricultural pest.

• DOI: 10.1016/j.jbc.2023.105421
• 发表时间: 2023-12
• 期刊: JOURNAL OF BIOLOGICAL CHEMISTRY
• 影响因子: 4.8
• 作者: Arriaza, Ricardo Hernandez;Abiskaroon, Brendan;Patel, Megha;Daneshian, Leily;Kluza, Anna;Snoeck, Simon;Watkins, Maxwell B.;Hopkins, Jesse B.;Van Leeuwen, Thomas;Grbic, Miodrag;Grbic, Vojislava;Borowski, Tomasz;Chruszcz, Maksymilian
• 通讯作者: Chruszcz, Maksymilian

Small Angle X-ray Diffraction as a Tool for Structural Characterization of Muscle Disease.

• DOI: 10.3390/ijms23063052
• 发表时间: 2022-03-11
• 期刊: International journal of molecular sciences
• 影响因子: 5.6
• 作者: Ma W;Irving TC
• 通讯作者: Irving TC