Characteristics of COVID-19 in transgender people

跨性别者中 COVID-19 的特征

基本信息

批准号：
10757115
负责人：
Michael Goodman
金额：
$ 20.8万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-15 至 2026-05-31
项目状态：
未结题

项目摘要

PROJECT SUMMARY/ABSTRACT Transgender people may be disproportionally affected by the coronavirus infection disease 2019 (COVID-19) pandemic because they may face barriers to timely care and because of the possible effect of gender-affirming HT on COVID-19 disease severity. Based on these considerations, the overall goal of the proposed administrative supplement will be to collect and analyze additional data to characterize the COVID-19 epidemic in different subgroups of STRONG cohort members relative to matched cisgender controls. The proposed administrative supplement will include additional data collection for the ongoing parent project “An expanded national cohort study of transgender people” (R01AG066956). The five-year parent project, which is now in its second year, represents an expansion of the previously established Study of Transition, Outcomes and Gender (STRONG). STRONG is a cohort of transgender people enrolled in Kaiser Permanente (KP) integrated health care plans in Georgia, Northern California, Southern California, and the Mid-Atlantic States. The expanded cohort includes approximately 40,000 transgender persons matched with 800,000 male and female cisgender referents. We will use additional STRONG data to compare rates and types of COVID- 19 vaccination in transmasculine (TM) and transfeminine (TF) persons to cisgender controls, examine the incidence of the disease among transgender and cisgender individuals and investigate if transgender status, receipt of hormone therapy, and levels of hormones, play a role in COVID-19 severity. A unique feature of the proposed analysis is that it considers both the biological variable of sex as well as the social, environmental, cultural, and behavioral factors that define gender – a distinction clearly outlined in the Trans-NIH Strategic Plan. 1

项目摘要/摘要跨性别者可能会受到2019年冠状病毒感染疾病（COVID-19）的不成比例影响大流行是因为它们可能面临及时关心的障碍，并且由于性别肯定的可能影响 HT关于199疾病严重程度的HT。基于这些考虑，提议的总体目标行政补充剂将是收集和分析其他数据以表征COVID-19的流行病在强大的队列构件的不同亚组中，相对于匹配的顺式控制。拟议的管理补充剂将包括正在进行的父母项目的其他数据收集 “跨性别人群的全国人队列研究扩大”（R01AG066956）。五年的父母项目，现在已进入第二年，代表了先前建立的过渡研究的扩展，结果和性别（强大）。 Strong是一组跨性别者（KP）佐治亚州，北加州，南加州和大西洋中部的综合医疗计划国家。扩展的队列包括大约40,000名跨性别者与80万男性相匹配和雌性的赋形剂。我们将使用其他强数据来比较率的速率和类型 19跨性质（TM）和trandfeminine（TF）的疫苗接种以进行顺式控制，检查跨性别者和sisgender个体中该疾病的发病率，并调查跨性别状况，是否收到马酮治疗和骑马水平的水平，在Covid-19的严重程度中起作用。一个独特的特征拟议的分析是，它既考虑性别的生物学变量，又考虑社会，环境，定义性别的文化和行为因素 - 在Trans-NIH战略中明确概述了一个区别计划。 1

项目成果

期刊论文数量（4）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Prevalence of self-inflicted injuries among transgender and gender diverse adolescents and young adults compared to their peers: an examination of interaction with mental health morbidity.

与同龄人相比，跨性别和性别多样化青少年和年轻人的自伤发生率：与心理健康发病率相互作用的检查。

DOI：
10.1016/j.annepidem.2023.03.003
发表时间：
2023
期刊：
Annals of epidemiology
影响因子：
5.6
作者：
Pampati,Sanjana;DanaFlanders,W;Zhang,Qi;Ahmedani,BrianK;Bhasin,Shalender;Getahun,Darios;Lash,TimothyL;McCracken,Courtney;Sandberg,DavidE;Silverberg,MichaelJ;Tangpricha,Vin;Vupputuri,Suma;Goodman,Michael
通讯作者：
Goodman,Michael

Understanding cardiovascular disease among transgender people: the journey continues.

了解跨性别者的心血管疾病：旅程仍在继续。