Johns Hopkins O'Brien Center to Advance Kidney Health Equity

约翰霍普金斯奥布莱恩中心致力于促进肾脏健康公平

• 批准号: 10747703
• 负责人: DEIDRA CANDICE CREWS
• 金额: $ 85.78万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10747703
• 关键词: Address; Advisory Committees; Basic Science; Behavior Therapy; Biometry; Brain; Calibration; Clinical; Clinical Research; Clinical Sciences; Cohort Studies; Collaborations; Communities; Consultations; Diet; Dietary Assessment; Discipline; Discrimination; Disparity; Disparity population; Education; Ensure; Equation; Ethnic Origin; Fostering; Gender; Germ-Free; Goals; Health; Health Food; Health Promotion; Housing; Incubators; Inequity; Infrastructure; Intervention; Intervention Studies; Joints; Kidney; Kidney Diseases; Laboratories; Lead; Mus; Nephrology; Periodicals; Phenotype; Population Heterogeneity; Prevention Research; Proteomics; Protocols documentation; Quality Control; Race; Recommendation; Research; Research Design; Research Personnel; Resource Development; Resources; Risk; Services; Sex Differences; Societies; Socioeconomic Status; Stress; Structural Racism; Students; System; Translations; Validation; biomedical resource; burden of illness; career; dietary; epidemiology study; experience; gut microbiota; health disparity; health equity; health inequalities; humanized mouse; innovation; marginalization; marginalized community; marginalized population; microbiome; novel; outreach; population health; pre-clinical; pre-clinical research; programs; social; social disparities; social health determinants; social stressor; socioeconomics; summer student; tool; translational scientist

OVERALL ABSTRACT Disparities in kidney health are profound; and for decades, have been documented for socially marginalized populations, yet little progress has been made to mitigate them. The overarching goal of the Johns Hopkins O’Brien Center to Advance Kidney Health Equity (JHOC) is to harness the collective expertise of basic, clinical and translational researchers at Johns Hopkins to serve as a national resource for investigators addressing the fundamental question of: what are the underlying mechanisms responsible for profound disparities in kidney health and how can they be mitigated? We will leverage the strengths and existing infrastructure of the Johns Hopkins Division of Nephrology, the Welch Center for Prevention, Epidemiology and Clinical Research and the Johns Hopkins Center for Health Equity. JHOC will include; 3 integrated cores (Administrative, Biomedical Resource and Resource Development); an Executive Committee; an Internal Advisory Committee, and a Community Advisory Board. Together, we will (1) provide an innovative portfolio of research services, resources, and tools for investigators to understand and ameliorate disparities in kidney disease; (2) develop new and refine existing resources as part of a dynamic incubator space for the conduct of basic and clinical research relevant to advancing kidney health equity; (3) transfer mature resources to the Biomedical Resource Core to be shared with the community; (4) plan and execute an annual Summer Student Enrichment Program which leverages a long-standing partnership with a Johns Hopkins program for students from socioeconomically under-resourced backgrounds; (5) foster the careers of early-stage investigators by promoting trans-disciplinary and cross-sector collaboration that will attract investigators from fields not traditionally involved in kidney health equity research; and (6) collaborate with the National Coordinating Center to prioritize external requests for resources and enhance national outreach. JHOC will support investigators conducting pre-clinical (basic), clinical or population health research addressing kidney health disparities, and will make recommendations to inform strategies, interventions, and approaches aimed at achieving kidney health equity.

全面的 抽象的 肾脏健康的差异是深远的。数十年来，已被记录为社会边缘化 人群，但几乎没有进步来减轻他们。约翰·霍普金斯的总体目标 奥布莱恩（O'Brien 并翻译了约翰·霍普金斯（Johns Hopkins）的研究人员，作为调查人员的国家资源 基本问题的问题：肾脏造成深远差异的基本机制是什么 健康，如何缓解它们？我们将利用约翰群岛的优势和现有基础设施 霍普金斯肾脏科，韦尔奇预防，流行病学与临床研究中心 约翰·霍普金斯卫生公平中心。 JHOC将包括； 3个综合核心（行政，生物医学） 资源和资源开发）；执行委员会；内部咨询委员会和 社区顾问委员会。我们将共同（1）提供研究服务的创新组合， 研究人员的资源和工具可以理解和改善肾脏疾病的分布； （2）发展 新的和完善现有资源，作为动态孵化器空间的一部分，用于进行基本和临床 与促进肾脏健康公平有关的研究； （3）将成熟资源转移到生物医学资源 要与社区共享的核心； （4）计划并执行年度夏季学生丰富计划 它利用与约翰·霍普金斯计划的长期合作伙伴关系，为 资源不足的背景； （5）培养早期研究人员的职业 促进跨学科和跨部门的合作，这将吸引来自领域的调查员 传统上参与肾脏健康公平研究； （6）与国家协调合作 中心要优先考虑资源并增强国家宣传。 JHOC将支持 进行临床前（基本），临床或人口健康研究的研究人员针对肾脏健康 差异，并将提出建议，以告知旨在的策略，干预措施和方法 实现肾脏健康平等。