Cross-Species Multidisciplinary Training in Alcohol Research

酒精研究的跨物种多学科培训

• 批准号: 10628897
• 负责人: MICHAEL F MILES
• 金额: $ 38.83万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10628897
• 关键词: Training; alcohol research; multidisciplinary

This revised application proposes a new T32 Institutional National Research Service Award with five years of support to fund Cross-Species Multidisciplinary Training in Alcohol Research, comprising four pre-doctoral and two postdoctoral trainees. Virginia Commonwealth University (VCU) has a history of excellence in the alcohol and drug abuse fields, ranking 7th nationally in currently active NIAAA awards (n=36). Major existing research or training funding include: 80 NIDA or NIAAA currently funded projects, NIAAA P50 supported VCU Alcohol Research Center (VCU-ARC), 12 individual F-awards to VCU trainees (7 NIAAA, 5 NIDA), NIDA T32- supported training program now in its 46th year of continuous funding, NIMH T32 training program funded for over 20 years, and a recently funded Medical Scientist Training Program T32. A focal point for alcohol research at VCU is the VCU Alcohol Research Center (VCU-ARC), now in its 12th year of NIAAA support with P50 funding renewed in 2020. VCU-ARC pursues an integrated cross-species program of genetic, genomic, behavioral and molecular studies to identify genes, gene networks and genetic variants contributing to risk and mechanisms of alcohol use disorder (AUD). VCU-ARC and the overall excellence in alcohol research at VCU make this a fertile training environment across multiple VCU departments or institutes. These include: the Virginia Institute for Psychiatric and Behavioral Genetics (VIPBG) and the Departments of Pharmacology & Toxicology, Human and Molecular Genetics, Psychology, Psychiatry, Internal Medicine and the Program in Neuroscience. The cross-species academic scope will include a 2 year, monthly Foundations of Alcohol Research lecture series, monthly research seminars in VCU ARC, a trainee-led alcohol research journal club, rigorous departmental-specific core courses and advanced electives, a high level of collaboration among mentors to include reciprocal service on thesis committees, multiple excellent seminar series, and required attendance at national or international alcohol research meetings. Multiple active VCU initiatives will increase diversity of trainees, augment retention of under-represented minority faculty and enhance mentor training. Specific major program strengths include: i) broad cross-species expertise of faculty in behavioral pharmacology, psychiatry, genetics, neuroscience, statistics, neuroimaging, data science and psychology; ii) highly productive research environment with accomplished, well-funded faculty; iii) extensive experience and excellent track record of a diverse faculty in training at this level; iv) access to large, informative datasets collected at VCU; v) instruction in responsible conduct of research utilizing an innovative text from a VCU expert in this field; and vi) a unique atmosphere and strong track record at VCU for support of diversity with multiple funded programs for such efforts. This training program thus offers a broad-based, cross-species training in alcohol research in an environment of research excellence and respect for diversity.

该修订后的申请提出了新的T32机构国家研究服务奖，五年 支持在酒精研究中资助跨物种的多学科培训，包括四个博士前和 两名博士后学员。弗吉尼亚联邦大学（VCU）拥有卓越的酒精历史 和药物滥用领域，在目前活跃的NIAAA奖项中排名全国第七（n = 36）。现有的主要研究 或培训资金包括：80个NIDA或NIAAA目前资助的项目，NIAAA P50支持VCU酒精 研究中心（VCU-ARC），12个个人F-Awards of VCU受训者（7 NIAAA，5 NIDA），NIDA T32-- NIMH T32培训计划现在是支持培训计划的第46年，该计划资助 20多年来，以及最近资助的医学科学家培训计划T32。酒精的焦点 VCU的研究是VCU酒精研究中心（VCU-ARC），现已在NIAAA支持的第12年中获得 P50资金于2020年续签。VCU-ARC追求遗传，基因组，基因组的综合跨物种计划 行为和分子研究，以鉴定有助于风险和的基因，基因网络和遗传变异 酒精使用障碍的机制（AUD）。 VCU-ARC和VCU酒精研究的总体卓越 在多个VCU部门或机构中，使其成为肥沃的培训环境。这些包括： 弗吉尼亚精神和行为遗传学研究所（VIPBG）以及药理学部门 毒理学，人类和分子遗传学，心理学，精神病学，内科和该计划 神经科学。跨物种学术范围将包括2年的每月酒精基础 研究讲座系列，VCU ARC的每月研究研讨会，由实习生领导的酒精研究俱乐部， 严格的部门特定核心课程和高级选修课，这是高度合作 指导者将在论文委员会，多个出色的研讨会系列中包括相互服务，并需要 参加国家或国际酒精研究会议。多个主动VCU计划将增加 学员的多样性，增强代表性不足的少数族裔教师的保留以及增强导师培训。 具体的主要计划优势包括：i）行为方面的广泛跨物种专业知识 药理学，精神病学，遗传学，神经科学，统计，神经影像学，数据科学和心理学； ii） 高产的研究环境，拥有丰富的资金丰富的教师； iii）丰富的经验和 在此级别的培训中，多样化的教师的出色记录； iv）访问大型，信息丰富的数据集 在VCU收集； v）使用VCU的创新文本进行负责任的研究指导 该领域的专家；和vi）在VCU上的独特氛围和良好的往绩，以支持多样性 多个资助的计划进行此类努力。因此，该培训计划提供了一个基于广泛的跨物种 在研究卓越和尊重多样性的环境中，酒精研究培训。