Toward measures and behavioral trials for effective online AUD recovery support

采取措施和行为试验以提供有效的在线澳元复苏支持

• 批准号: 10643056
• 负责人: Jason Colditz
• 金额: $ 16.5万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10643056
• 关键词: Adult; Alcohol consumption; Behavior; Behavior Therapy; Behavior assessment; Behavioral; Behavioral trial; COVID-19 pandemic; Classification; Clinical; Clinical Treatment; Clinical Trials; Clinical Trials Design; Code; Collaborations; Computing Methodologies; Conceptual Domain; Coping Skills; Data; Data Reporting; Development; Effectiveness; Emotional; Feedback; Focus Groups; Foundations; Frequencies; Funding; Goals; Health; Health Services Accessibility; Heterogeneity; Human; Intervention; Learning; Measurement; Measures; Mentors; Mentorship; Methods; Modeling; National Institute on Alcohol Abuse and Alcoholism; Natural Language Processing; Observational Study; Outcome; Participant; Pathway interactions; Patient Self-Report; Pattern; Personal Satisfaction; Persons; Procedures; Process; Psychological reinforcement; Psychometrics; Randomized, Controlled Trials; Recommendation; Recovery; Recovery Support; Research; Research Personnel; Social Identification; Social Processes; Social support; Statistical Data Interpretation; Structure; Surveys; Technology; Text; Time; Training; Work; acceptability and feasibility; addiction; alcohol seeking behavior; alcohol use disorder; behavioral clinical trial; behavioral construct; career; concept mapping; cost effective; dashboard; deep learning; effectiveness evaluation; evidence base; evidence based guidelines; experience; feasibility trial; health science research; human centered design; improved; insight; instrument; multidisciplinary; new technology; online intervention; peer; peer support; prospective; randomized, clinical trials; social; social media; social observations; therapy development; tool

PROJECT SUMMARY/ABSTRACT Alcohol Use Disorder (AUD) is a common and serious health condition. The COVID-19 pandemic worsened AUD trajectories and heightened barriers to accessing treatment and peer support that are effective in improving AUD outcomes. A growing number of people are seeking AUD recovery support via popular Online AUD Recovery Support (OARS) forums on social media platforms. OARS forums lower barriers to social support in recovery, are widely available, and show promise for improving AUD outcomes. However, as there are no rigorous clinical trials focusing on OARS forum participation, there is insufficient evidence to recommend them as effective in supporting AUD recovery. Such trials are challenging, given the variety of OARS forums and the myriad approaches to participation (e.g., frequency of use, support sought or given). My long-term career goal is to become an independent investigator and leader in development, implementation, and assessment of behavioral approaches to OARS that are effective in improving AUD recovery outcomes. To fill crucial gaps in my expertise, I have four training objectives: (1) Conceptual frameworks of AUD and AUD recovery processes, to provide strong conceptual foundations for this work; (2) Training in focus group methods for concept mapping and human-centered design, to collect data from OARS forum users that informs subsequent self-report scale and intervention development; (3) Training in advanced methods for Natural Language Processing (NLP) text classification, to advance rigorous observational research of OARS behaviors in naturalistic settings; and (4) Training in clinical trial design for behavioral interventions, to develop and conduct trials that assess the effectiveness of OARS participation on AUD outcomes. I have assembled a multidisciplinary mentoring team of AUD and addiction recovery researchers with a strong track record of NIAAA funding and mentorship. My consultants provide necessary expertise in social processes of recovery, psychometrics, advanced methods in NLP, and clinical trial development and statistical analysis. The proposed K01 research builds upon my prior work focusing on patterns of OARS participation and social support. I propose an OARS Behavioral Pathway Model (OARS-BPM) to characterize observable behavior of OARS participation and social support, which are associated with development of AUD coping skills and a recovery-oriented social identity. I will develop self-report scales and corresponding NLP text classifiers to identify latent constructs of OARS behavior. To assess and refine OARS-BPM, I will elicit focus group feedback from OARS users and apply NLP text classifiers to characterize user behavior from public OARS forums. Based on these findings, I will conduct a pilot randomized clinical trial to assess feasibility and acceptability of an OARS-BPM based intervention to encourage structured OARS participation over 3 months. Thus, I will develop necessary self-report and NLP-based measurement tools as well as a behavioral clinical trial framework, which will potentiate the first randomized controlled trials of OARS participation on improving AUD outcomes.

项目摘要/摘要 酒精使用障碍（AUD）是一种常见且严重的健康状况。 COVID-19大流行恶化 AUD轨迹和获得治疗和同伴支持有效的障碍 改善澳元的结果。越来越多的人通过在线流行寻求AUD恢复支持 社交媒体平台上的AUD恢复支持（OARS）论坛。桨论坛较低的社会障碍 恢复方面的支持是广泛可用的，并显示出改善AUD结果的希望。但是，如那样 没有针对桨论坛参与的严格临床试验，没有足够的证据表明 向他们推荐有效支持AUD恢复。考虑到多种多样 OARS论坛和无数参与的方法（例如，使用频率，寻求或给出）。我的 长期职业目标是成为发展，实施，实施的独立研究者和领导者 以及评估有效改善AUD恢复结果的桨的行为方法。 为了填补我的专业知识的关键空白，我有四个培训目标：（1）AUD和AUD的概念框架 恢复过程，为这项工作提供强大的概念基础； （2）焦点小组培训 概念映射和以人为本设计的方法，从桨论坛用户那里收集数据 随后的自我报告规模和干预发展； （3）自然高级方法的培训 语言处理（NLP）文本分类，以提高对桨行为的严格观察研究 在自然主义的环境中； （4）临床试验设计培训行为干预措施，开发和 进行试验，以评估船桨参与对AUD结果的有效性。我已经组装了 多学科指导团队由AUD和成瘾恢复研究人员具有很强的记录 NIAAA资金和指导。我的顾问在康复社会过程中提供必要的专业知识， 心理计量学，NLP中的高级方法以及临床试验开发和统计分析。 拟议的K01研究基于我先前的工作，重点是桨的参与和社会方式 支持。我提出了一个桨行为途径模型（OARS-bpm），以表征可观察的行为 OARS的参与和社会支持，与AUD应对技巧的发展有关 面向恢复的社会身份。我将开发自我报告量表和相应的NLP文本分类器 确定桨行为的潜在构造。为了评估和完善桨BPM，我将引起焦点小组反馈 来自OARS用户并应用NLP文本分类器以表征来自公共桨论坛的用户行为。基于 根据这些发现，我将进行一项试验随机临床试验，以评估 基于oars-bpm的干预措施，以鼓励3个月内的结构化船上参与。因此，我会发展 必要的自我报告和基于NLP的测量工具以及行为临床试验框架， 将增强船桨参与的第一个随机对照试验，以改善AUD结果。