Predoctoral Training in the Pharmacological Sciences

药理学博士前培训

• 批准号: 10621722
• 负责人: David L. Roman
• 金额: $ 39.73万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10621722
• 关键词: Science; Training; pharmacologic; pre-doctoral

________________________ ____PROJECT SUMMARY / ABSTRACT __ ____ ___ _________________ The Pharmacological Sciences Training Program (PSTP) at the University of Iowa seeks to achieve interdisciplinary and integrated training of a diverse cohort of graduate students in Pharmacological Sciences. The result will be successful PhDs who are well prepared for career and leadership positions in pharmacology in academia, government (e.g. regulatory agencies), pharmaceutical companies, biotechs, research institutes, and science-related fields. In addition to training PhDs well-positioned for career success, our outcomes include publication of first-author and collaborative papers, success in obtaining individual, nationally- competitive fellowships, at or below-average time to degree, and establishing an inclusive and supportive environment conducive to intellectual growth and scientific development. This program is built upon a foundation of an existing Interdisciplinary T32 in Pharmacological Sciences established in 2004, and we build on elements of this program with new programmatic, evaluation, and curricular plans, which bring greater focus on mentorship, team science, rigorous and reproducible research, and career development. The pool of trainees eligible for this program at the University of Iowa is talented and deep. Drawing from 53 mentor laboratories in 13 degree-granting programs across 3 colleges (Medicine, Pharmacy, Liberal Arts & Sciences), we aim for 6 trainees per year to join our program, each appointed for two years (their 2nd and 3rd years of graduate study) for a total of 12 trainee positions. We request funding of only 9 positions, however, because the three participating colleges have pledged support of one matching position each. Our 6 proposed trainees are selected annually from a large pool of strong applicants (5-year average: 19). Trainee selection is a holistic evaluation process that considers fairness and diversity, in addition to strength of the applicant. This PSTP aims to be a highly effective mechanism for interdisciplinary training in the Pharmacological Sciences regardless of departmental affiliation. Even after financial support ends, trainees remain actively engaged in the PSTP through and past graduation. Our core course sequence, Principles of Pharmacology and Pharmacogenetics & Pharmacogenomics, provides trainees a deep understanding of classical and modern pharmacology. Additional courses are required, such as Advanced Problem Solving in Pharmacological Sciences, in which trainees work as a team to design collaborative research plans, while Basic Biostatistics and Experimental Design, and Mastering Reproducible Science focus on rigor and reproducibility, a theme threaded throughout all activities of the PSTP. Science Communication in the Digital Age and PSTP-organized career workshops are offerings that broaden the development of career skills to better prepare our trainees for the job market. These courses lead to cohort-building for our trainees from different programs, as they progress through classes and program activities together including research retreats, summer brown bag discussion luncheons, as well as semi- weekly interactions during Pharmacology Seminar.

_______________________ ____项目摘要/摘要 __ ____ ___ _________________ 爱荷华大学药理学科学培训计划 (PSTP) 旨在实现 对药理学科学研究的多元化研究生群体进行跨学科和综合培训。 结果将是成功的博士，他们为药理学的职业和领导职位做好了充分的准备 在学术界、政府（例如监管机构）、制药公司、生物技术、研究机构、 和科学相关领域。除了培养为职业成功做好准备的博士外，我们的成果还包括 发表第一作者和合作论文，成功获得具有全国竞争力的个人论文 奖学金，以低于平均水平的时间获得学位，并建立一个包容和支持性的环境 有利于智力成长和科学发展。该计划建立在以下基础之上 现有的药理学跨学科 T32 成立于 2004 年，我们以此为基础 具有新的计划、评估和课程计划的计划，更加注重指导、团队 科学、严谨且可重复的研究以及职业发展。 爱荷华大学有资格参加该项目的学员人才济济，实力雄厚。绘图自 3 个学院（医学、药学、文科和 科学），我们的目标是每年有 6 名学员加入我们的计划，每人任命两年（他们的第二和第三 研究生学习年），总共 12 个实习生职位。我们只要求为 9 个职位提供资金，但是， 因为三所参与的学院已承诺各支持一个匹配职位。我们提出的6个 每年都会从大量优秀申请者中选拔受训人员（5 年平均：19 人）。实习生的选择是 除了申请人的实力之外，整体评估过程还考虑公平性和多样性。 该 PSTP 旨在成为药理学跨学科培训的高效机制。 科学不分部门隶属关系。即使在财政支持结束后，学员们仍然积极主动 毕业后一直从事 PSTP。我们的核心课程序列、药理学原理和 药物遗传学和药物基因组学，让学员深入了解古典和现代 药理。需要额外的课程，例如药理学高级问题解决 科学，其中学员作为一个团队设计协作研究计划，而基础生物统计学和 实验设计和掌握可重复性科学侧重于严谨性和可重复性，这是一个主题 贯穿 PSTP 的所有活动。数字时代的科学传播和 PSTP 组织的职业 研讨会旨在扩大职业技能的发展，让学员更好地为工作做好准备 市场。这些课程为来自不同项目的学员建立了队列，随着他们的进步 一起进行课程和项目活动，包括研究静修、夏季棕色包讨论午餐会、 以及药理学研讨会期间每半周的互动。