Nutritional Biocliemistry and Metabolomics Core

营养生物化学和代谢组学核心

• 批准号: 8132730
• 负责人: Melinda A. Beck
• 金额: $ 15.89万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8132730
• 关键词: Biochemical; Biochemical Markers; Biological Assay; Biological Markers; Collaborations; Consultations; Core Facility; Data; Disease; Documentation; Enzyme-Linked Immunosorbent Assay; Epidemiologist; Epidemiology; Equipment; Flow Cytometry; Gel; Human Resources; Measures; Metabolic; Microscope; Molecular; Molecular Biology Techniques; Nutritional; Nutritional Biochemistry; Nutritional status; Obesity; Process; Quality Control; Reader; Research; Research Personnel; Sampling; System; Techniques; Training; Work; cost effective; digital; extracellular; light microscopy; metabolomics; nutrition

The Nutritional Biochemistry and Metabolomics Core facility provides investigators performing nutritionally related research with standardized and quality controlled biochemical assays, with the ability to leam molecular biology techniques or have the core process samples for molecular biological assays, and with access to equipment (e.g. flow cytometry, icycler, spectrophotometer, Cobas mira system, gel documentation, fluorescent and light microscopy with digital camera. ELISA reader and plate washer, ultracentrifuge, X24 extracellular flux analyzer). Many of our users are nutritional epidemiologists or nutritional interventionists who do not have wet lab space, yet they require biomarker measures (often routine assays) for their studies and therefore, need a Core facility to analyze their samples. Biomari<er consultation is also a core strength. Core personnel work with investigators to detennine the appropriate biomaricers for the study question as well as appropriate sample handling. In addition. Core Personnel provide expertise in data interpretation for users.

营养生物化学和代谢组学核心设施为研究人员提供通过标准化和质量控制的生化测定进行营养相关研究的研究人员，能够学习分子生物学技术或拥有分子生物学测定的核心过程样品，并能够使用设备（例如流式细胞术、 icycler、分光光度计、Cobas mira 系统、凝胶记录仪、带 ELISA 读数器和洗板机的荧光和光学显微镜、超速离心机、X24 细胞外通量分析仪。我们的许多用户是营养流行病学家或营养干预专家，他们没有湿实验室空间，但他们需要生物标志物测量（通常是常规测定）进行研究，因此需要核心设施来分析他们的样本。 Biomari 咨询也是一项核心优势。核 工作人员与研究人员合作，确定适合研究问题的生物标志物以及适当的样品处理。此外。核心人员为用户提供数据解释方面的专业知识。