Training Program in Translational Cardiovascular Science

转化心血管科学培训项目

• 批准号: 10270772
• 负责人: Lee Lochbaum Eckhardt
• 金额: $ 51.18万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-17 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10270772
• 关键词: Cardiovascular system; Science; Training Programs

PROJECT SUMMARY/ABSTRACT This application seeks renewal for Years 21-25 of the Training Program in Translational Cardiovascular Science (TPTCS) within the School of Medicine and Public Health Cardiovascular Research Center (CVRC) at the University of Wisconsin-Madison. The CVRC is a campus-wide interdisciplinary research center with faculty and research members from 31 departments in seven schools and colleges, providing a rich environment targeting cardiovascular disease through basic research, clinical investigation, diagnosis and therapy, and public education. The TPTCS training program uniquely creates basic research training for postdoctoral MDs and PhDs (four positions) as well as predoctoral trainees (five positions) with the goal of training scientists who will be capable of thinking and working “from molecule to bedside.” The practical immediate objectives are to attract and train clinicians in basic research, and to attract and train graduate and postdoctoral (PhD) students in clinically motivated basic science. The TPTCS aims to appoint physicians as part of their resident and fellow training to half the postdoctoral positions. One of the long-standing strengths of the program emerging from annual program evaluation is its integration of training among predoctoral students, basic science postdoctoral trainees, and clinical fellows who work side-by-side in journal clubs, in seminar series, and at the bench in laboratories. This blending and sharing of different trainee perspectives is foundational to the goals of the program and creates esprit de corps. The 27 trainers of the TPTCS have been selected from members of the CVRC for the clinical relevance of their science in the focus areas (heart failure/regenerative medicine, arrhythmias/ion channel research, and atherosclerosis/vascular biology), their training records, and the overall robustness and activity of their peer-reviewed research programs. Training takes place at the University of Wisconsin-Madison and exploits the strong institutional support and environment for such training, as well as the established working relationships between clinical and basic science departments and faculty both within the School of Medicine and Public Health and the University at large. Trainers and trainees all participate in core activities that define the program as a cohesive entity. Several innovations are introduced in this renewal, including enhanced clinical integration for the basic science trainees and greater professional development opportunities to prepare all trainees for the next stages in their careers. Appointees to the program to date are extremely strong and program outcomes have been excellent. The scientists and physician-scientists trained in this translational cardiovascular science program are in unique positions to apply basic scientific knowledge to benefit patients with cardiovascular disease, the foremost cause of mortality among Americans.

项目摘要/摘要 该申请寻求续签翻译心血管培训计划21 - 25年 医学和公共卫生心血管研究中心（CVRC）的科学（TPTC） 威斯康星大学麦迪逊分校。 CVRC是一个与校园范围的跨学科研究中心 来自七个学校和大学的31个部门的教师和研究成员，提供富裕 通过基础研究，临床研究，诊断和靶向心血管疾病的环境 治疗和公共教育。 TPTCS培训计划独特地创建了基础研究培训 博士后MDS和PHD（四个职位）以及前学员（五个职位），目的是 培训将“从分子到床边”思考和工作的科学家。实用 直接的目标是吸引和培训临床医生在基础研究中，吸引和培训毕业生和 临床动机基础科学的博士后（博士学位）学生。 TPTC的目标是任命医生 他们的居民和培训的一部分是博士后职位的一半。长期存在的优势之一 年度课程评估中出现的计划是其在专业学生中培训的整合， 基础科学博士后学员和在期刊俱乐部并排工作的临床研究员， 系列，以及实验室的替补席。这种融合和分享不同学员观点的是 该计划目标的基础，并创建了Esprit de Corps。 TPTC的27培训师已经 从CVRC成员中选择其科学在焦点领域的临床相关性（心脏 衰竭/再生医学，心律失常/离子通道研究和动脉粥样硬化/血管生物学） 培训记录，以及经过同行评审研究计划的整体鲁棒性和活动。训练 在威斯康星大学麦迪逊分校举行，并利用强大的机构支持和 此类培训的环境以及临床和基本之间已建立的工作关系 科学系和医学和公共卫生学院内的教师以及大学 大的。培训师和学员都参加了将该计划定义为凝聚力实体的核心活动。 在此续签中引入了一些创新，包括增强基础科学的临床整合 受训者和更大的专业发展机会，为所有受训者准备下一个阶段的学员 职业。迄今为止，该计划的AppPointees非常强大，程序成果非常出色。 在这项翻译的心血管科学计划中训练的科学家和身体科学家正在 采用基本科学知识的独特立场使心血管疾病患者受益， 美国人死亡的最大原因。