Penn TMC: Coordination Core

Penn TMC：协调核心

• 批准号: 10269926
• 负责人: JUNHYONG KIM
• 金额: $ 12.8万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-24 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10269926
• 关键词: 3-Dimensional; Adopted; Anatomic Models; Attention; Biological Assay; Cells; Cellular biology; Clinical; Communication; Complex; Data; Deposition; Ensure; Event; Generations; Genome; Geography; Goals; Human BioMolecular Atlas Program; Institutes; Leadership; Molecular; National Human Genome Research Institute; Production; Protocols documentation; Research Personnel; Resource Development; Resources; Sampling; Structure; System; Tissues; United States National Institutes of Health; Work; experience; female reproductive system; frontier; functional group; genome sciences; human female; meetings; molecular scale; multimodality; operation; programs; symposium; three-dimensional modeling; working group

The Coordination Core’s goal is to manage and coordinate all activities of the Penn Center for Multi- Scale Molecular Mapping of the Female Reproductive System. The Center’s goal is to create a multi- modal, multi-scale molecular characterization of ~700 different samples of the human female reproductive system. We will coordinate the activities of the Penn Center for Multi-Scale Molecular Mapping of the Female Reproductive System. We will create a management structure with a leadership group of the MPIs and a Project Manager and four Functional Groups, each led by an expert investigator. We will create a single workstream with the four functional groups: (1) Clinical Sampling Group; (2) 3D Modeling Group; (3) Molecular Assay Group; and (4) Data Coordination Group. We will use electronic work systems for communication and project management. Detailed monthly production goals will be established and managed by the MPIs and the project manager. In addition, we will coordinate activities of the Penn Center with the HuBMAP consortium groups. The Coordination Core will manage all interactions with the HuBMAP consortium, NIH Program Staff, and other outside entities. We will participate in all meetings, conference calls, and coordination events. We will work with other TMCs to collaborate in establishing robust protocols and adopting the assays deployed by other centers. We will coordinate with the HIVE groups to deposit and disseminate the data, as well as to develop a common 3D anatomical model and coordinate framework for the female reproductive system. The activities of the Coordination Core will ensure efficient operations of the Penn Center and help meet the milestones of our public resource generation project.

协调核心的目标是管理和协调宾夕法尼亚大学多边中心的所有活动 该中心的目标是创建一个多尺度的女性生殖系统分子图谱。 对约 700 个不同的人类女性样本进行模态、多尺度分子表征 我们将协调宾夕法尼亚大学多尺度分子中心的活动。 绘制女性生殖系统图 我们将建立一个具有领导层的管理结构。 由 MPI 和一名项目经理组成的小组以及四个职能小组，每个小组由一名专家调查员领导。 我们将创建一个包含四个职能组的单一工作流：(1) 临床采样组；(2) 3D 建模组；（3）分子分析组；和（4）数据协调组。 沟通和项目管理的工作系统将是详细的每月生产目标。 由 MPI 和项目经理建立和管理。此外，我们将协调活动。 宾夕法尼亚大学中心与 HuBMAP 财团的协调核心将管理所有事宜。 我们将与 HuBMAP 联盟、NIH 项目人员和其他外部实体进行互动。 我们将与其他 TMC 合作，参与所有会议、电话会议和协调活动。 我们将合作建立强大的协议并采用其他中心部署的检测方法。 与 HIVE 团体协调保存和传播数据，并制定共同的 女性生殖系统的 3D 解剖模型和坐标框架。 协调核心将确保宾夕法尼亚中心的高效运营，并帮助实现以下里程碑： 我们的公共资源生成项目。