Duke Summer Training in Academic Research (Duke's STAR)

杜克大学夏季学术研究培训（杜克大学之星）

• 批准号: 10614911
• 负责人: DANIEL K. BENJAMIN
• 金额: $ 10.78万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10614911
• 关键词: Adverse event; Biometry; Child; Child Health; Childhood; Clinical Pharmacology; Clinical Research; Clinical Trials; Communication; Communities; Complement; Continuing Education; Data; Databases; Dose; Drug Kinetics; Education; Education Projects; Environment; Epidemiology; Faculty; Foundations; Funding; Future; Goals; High School Faculty; High School Student; Infant; Infrastructure; Instruction; Journals; Knowledge; Leadership; Learning; Link; Manuscripts; Medical; Medical Students; Mentors; Mentorship; Methods; National Center for Advancing Translational Sciences; National Institute of Child Health and Human Development; Nature; Network Infrastructure; Online Systems; Oral; Outcome; Participant; Pediatric Research; Pediatrics; Peer Review; Pharmaceutical Preparations; Pharmacoepidemiology; Physiology; Population Scientist Supplement (R25); Positioning Attribute; Principal Investigator; Process; Publications; Publishing; Qualifying; Recording of previous events; Research; Research Institute; Research Methodology; Research Personnel; Resources; Review Literature; Running; Safety; Schools; Science; Scientist; Series; Solid; Students; Therapeutic; Time; Training; Training Programs; Training Support; Underrepresented Minority; United States; United States National Institutes of Health; Universities; Work; Writing; body system; career; disadvantaged student; drug efficacy; drug metabolism; education research; experience; faculty mentor; graduate school preparation; high risk; high school; improved; knowledge base; meetings; member; mid-career faculty; older patient; organ growth; peer; prevent; programs; project-based learning; recruit; research faculty; science teacher; skills; success; summer program; summer research; teacher; text searching; tutoring; undergraduate research experience; undergraduate student; university student

The proposed Duke Summer Training in Academic Research program (referred to henceforth as “Duke's STAR” program) will provide a high-quality research experience for undergraduate students, high school students, and high school teachers during the summer academic break. The program will help attract young students to careers in science; provide opportunities for students to gain valuable research experience in preparation for graduate school; and enhance the skills of science teachers, enabling them to more effectively communicate the nature of the scientific process to their students. The proposed summer research program will expand and complement existing NIH-sponsored training programs already in place at Duke University under the leadership of the principal investigator, Daniel K. Benjamin Jr. As chair of the Pediatric Trials Network, Dr. Benjamin has broad oversight of 3–6 large pharmacoepidemiology projects every year, each of which requires well-defined, short-term, pre-study work that is ideally suited for a 9-week summer research experience and, as we have demonstrated with our previous R25 program, will result in publications for trainees. In addition, the Duke Clinical Research Institute (DCRI) offers formal educational and support programs for junior faculty, fellows, residents, and medical students with funding from internal DCRI resources as well as the NIH. The proposed program represents a critical piece in a continuum of NIH-supported training at the DCRI that runs the gamut from the high school level to mid-career faculty. In short, the program will be uniquely positioned within an established educational infrastructure with a track record of successful trainees. The summer research experience will take place over 9 weeks and will focus on pharmacoepidemiological research methodology and writing skills. Participants will be paired with Duke faculty to work on an original, hypothesis-driven project. For the first 2 weeks of the program, trainees will work with their faculty mentors to develop a solid knowledge base of a specific pharmacoepidemiologic question based on a thorough review of the literature. During weeks 2–8, the trainees will work in groups to develop a 6–10-page manuscript consisting of a description of the research question, specific aims, methods, and figures/tables for the study. During the final 2 weeks, trainees will refine their manuscripts and prepare oral presentations of their findings. Throughout this time, a medical writer will provide trainees with didactic instruction via small group sessions. Trainees will also work with their mentors throughout the course of the program to review their progress. At the program's conclusion, trainees will present the results of their work at the DCRI before an audience of their peers, pediatrics faculty and fellows, and other community members. Finally, trainees will be followed for 10 years using a web-based database to assess the training program's impact on their subsequent academic and professional trajectories. The proposed program will result in an improved pipeline of future scientists whose practical experience in pediatric clinical research will facilitate their entry into research careers.

拟议的杜克大学夏季学术研究计划培训（此后称为“杜克大学” Star”计划）将为本科生，高中提供高质量的研究经验 夏季学术休息期间的学生和高中老师。该计划将有助于吸引年轻人 学生从事科学职业；为学生提供有价值的研究经验的机会 为研究生院做准备；并提高科学老师的技能，使他们能够更有效 将科学过程的性质传达给学生。拟议的夏季研究计划 将在杜克大学扩大和完成现有的NIH赞助的培训计划 在首席研究员的领导下，小丹尼尔·本杰明（Daniel K. Benjamin Jr.）担任儿科试验主席 网络，本杰明博士每年都对3-6个大型药物电子学项目进行了广泛监督 这需要定义明确的短期，预研究的工作，非常适合为期9周的夏季研究 经验，正如我们在以前的R25计划中所展示的那样，将为 学员。此外，杜克临床研究所（DCRI）提供正规教育和支持 DCRI资源的资助 以及NIH。拟议的计划代表了由NIH支持的培训连续的关键作品 在从高中到中学教师的DCRI中。简而言之，该程序将是 独特地定位在既定的教育基础设施中，并具有成功的学员的往绩。 夏季研究经验将在9周内举行，并将重点放在药物电子学上 研究方法和写作技巧。参与者将与杜克大学的教师配对，以制作原创作品 假设驱动的项目。在计划的前两周，学员将与他们的教师导师合作 基于对 文学。在第2-8周内，学员将分组工作，开发一个6–10页的手稿，包括 研究问题的描述，特定的目的，方法和数字/表。在 最后2周，学员将完善手稿并准备他们的发现的口头介绍。自始至终 这次，医学作家将通过小组会议为受训者提供教学指导。学员会 在整个计划的整个过程中，还可以与他们的导师一起审查其进度。在计划的 结论，学员将在同龄人的观众面前向DCRI展示他们的工作结果， 儿科教师和研究员以及其他社区成员。最后，将追踪学员10年 使用基于Web的数据库来评估培训计划对其后续学术和 专业轨迹。拟议的计划将导致改进的未来科学家的渠道 小儿临床研究的实践经验将有助于他们从事研究职业。

项目成果

Diagnostic Utility of Cerebrospinal Fluid White Blood Cell Components for the Identification of Bacterial Meningitis in Infants.

脑脊液白细胞成分在婴儿细菌性脑膜炎鉴定中的诊断效用。

• DOI: 10.1093/jpids/piad087
• 发表时间: 2023
• 期刊: Journal of the Pediatric Infectious Diseases Society
• 影响因子: 3.2
• 作者: Lamb,AshleyE;Rent,Sharla;Brannon,AsiaJ;Greer,JonathanL;Ndey-Bongo,NyssaP;Cho,StephenH;Greenberg,RachelG;BenjaminJr,DanielK;Clark,ReeseH;Kumar,KaranR
• 通讯作者: Kumar,KaranR

Early-onset sepsis in term infants admitted to neonatal intensive care units (2011-2016).

• DOI: 10.1038/s41372-020-00860-3
• 发表时间: 2021-01
• 期刊: Journal of perinatology : official journal of the California Perinatal Association
• 作者: Polcwiartek LB;Smith PB;Benjamin DK;Zimmerman K;Love A;Tiu L;Murray S;Kang P;Ebbesen F;Hagstrøm S;Clark RH;Greenberg RG
• 通讯作者: Greenberg RG

In-hospital outcomes of premature infants with severe bronchopulmonary dysplasia.

• DOI: 10.1038/jp.2017.49
• 发表时间: 2017-07
• 期刊: Journal of perinatology : official journal of the California Perinatal Association
• 作者: Jackson W;Hornik CP;Messina JA;Guglielmo K;Watwe A;Delancy G;Valdez A;MacArthur T;Peter-Wohl S;Smith PB;Tolia VN;Laughon MM
• 通讯作者: Laughon MM

Evaluation of Gentamicin Exposure in the Neonatal Intensive Care Unit and Hearing Function at Discharge.

新生儿重症监护室庆大霉素暴露和出院时听力功能的评估。

• DOI: 10.1016/j.jpeds.2018.07.101
• 发表时间: 2018
• 期刊: The Journal of pediatrics
• 作者: Puia-Dumitrescu,Mihai;Bretzius,OliviaM;Brown,Nia;Fitz-Henley,JamesA;Ssengonzi,Rebecca;Wechsler,CarolineS;Gray,KeyariaD;BenjaminSr,DanielK;Smith,PBrian;Clark,ReeseH;Gonzalez,Daniel;Hornik,ChristophP
• 通讯作者: Hornik,ChristophP

Exchange transfusion safety and outcomes in neonatal hyperbilirubinemia.

• DOI: 10.1038/s41372-020-0642-0
• 发表时间: 2020-10
• 期刊: Journal of perinatology : official journal of the California Perinatal Association
• 作者: Wolf MF;Childers J;Gray KD;Chivily C;Glenn M;Jones L;Kpa M;McMannen T;Reyes I;Zimmerman KO;Clark RH;Greenberg RG
• 通讯作者: Greenberg RG