Southern California Clinical and Translational Science Institute

南加州临床与转化科学研究所

• 批准号: 10613592
• 负责人: Thomas A Buchanan
• 金额: $ 919.29万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10613592
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Contact PD/PI: Buchanan, Thomas A OVERALL COMPONENT Project Summary/Abstract The Southern California Clinical and Translational Science Institute (SC CTSI) is submitting this revision for a third cycle of Clinical and Translational Science Award (CTSA) funding at a time of dramatic growth and opportunity at our hub. The SC CTSI encompasses the University of Southern California (USC) and Children's Hospital of Los Angeles (CHLA), in close partnership with the Los Angeles County Department of Health Services. Our vision is to be a leader in clinical and translational research to benefit diverse communities and special populations. Our approach builds on past success, acknowledging the changing landscape of clinical and translational research (CTR), the priorities of the CTSA program, and the evolving needs of our researchers, trainees, patients and communities. Our scope leverages strengths in clinical, health system, and community research, education and training, within two overarching themes: diversity and impact. Diversity is reflected in the communities, health systems, and scientific disciplines we engage to improve health care and outcomes. Impact encompasses academic productivity as well as benefit to our workforce, health systems, patients, and communities. To pursue our vision in the context of our scope and themes, we propose six specific aims: (1) Workforce Development: Train a highly skilled workforce with the knowledge, skills, and attitudes to conduct rigorous and reproducible research focused on the evolving health needs of diverse communities. (2) Collaboration and Engagement: Create a culture in which team-based research, engaging all stakeholders and following sound principles of team science, is the standard approach to addressing complex challenges in health and research. (3) Integration: Engage our diverse communities to establish clinical research priorities; identify barriers to research; and develop, demonstrate and disseminate innovative approaches to assure fully partnered clinical research across communities and the lifespan. (4) Methods and Process: Apply principles of quality and process improvement to clinical and translational research to develop and share novel approaches to enhance efficiency, quality and impact. (5) Informatics: Provide an agile information ecosystem that encompasses research, clinical care, communities and their environment, providing a holistic view of health and disease and serving as the engine for discovery, innovation and insight. (6) CTSA Hub: Participate in CTSA network activities, conduct multi-site studies, adopt successful models from peers, and develop, demonstrate and disseminate innovative approaches. Achieving these aims will advance the discipline of CTR directed at improving health in diverse and underserved communities.

联系人 PD/PI：Buchanan, Thomas A 整体组成 项目概要/摘要 南加州临床与转化科学研究所 (SC CTSI) 正在提交此修订版以供 在急剧增长和 我们中心的机会。 SC CTSI 涵盖南加州大学 (USC) 和儿童医院 洛杉矶医院 (CHLA) 与洛杉矶县卫生部密切合作 服务。我们的愿景是成为临床和转化研究的领导者，造福不同的社区和 特殊人群。我们的方法建立在过去的成功基础上，承认临床环境的不断变化 和转化研究 (CTR)、CTSA 计划的优先事项以及我们不断变化的需求 研究人员、学员、患者和社区。我们的业务范围利用了临床、卫生系统和 社区研究、教育和培训，有两个总体主题：多样性和影响力。多样性是 反映在我们为改善医疗保健而参与的社区、卫生系统和科学学科中 结果。影响力包括学术生产力以及对我们的劳动力、卫生系统、 患者和社区。为了在我们的范围和主题的背景下实现我们的愿景，我们提出了六项建议 具体目标： (1) 劳动力发展：培养一支具备知识、技能和能力的高技能劳动力 开展严格且可重复的研究的态度，重点关注不同人群不断变化的健康需求 社区。 (2) 协作和参与：创建一种基于团队的研究、让所有人参与的文化 利益相关者并遵循团队科学的合理原则，是解决复杂问题的标准方法 健康和研究方面的挑战。 (3) 整合：让我们的多元化社区参与建立临床 研究重点；找出研究的障碍；并开发、展示和传播创新 确保跨社区和生命周期充分合作的临床研究的方法。 (四)方法与 流程：将质量和流程改进原则应用于临床和转化研究以开发 并分享提高效率、质量和影响力的新方法。 (5)信息学：提供敏捷的 信息生态系统，涵盖研究、临床护理、社区及其环境，提供 对健康和疾病的整体看法，并作为发现、创新和洞察力的引擎。 （6）CTSA 中心：参与 CTSA 网络活动，进行多站点研究，采用同行的成功模式， 开发、展示和传播创新方法。实现这些目标将推动 CTR 的学科旨在改善多元化和服务不足的社区的健康。