Parent-Infant Co-regulation of Sleep and Physiology in Families with Neglect

忽视家庭中亲子睡眠和生理的共同调节

• 批准号: 10611306
• 负责人: Samantha M Brown
• 金额: $ 13.08万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10611306
• 关键词: Address; Autonomic nervous system; Behavior; Behavior assessment; Behavioral; Biological; Biological Markers; Biological Process; Breathing; Child; Child Abuse and Neglect; Child Rearing; Child Welfare; Colorado; Consultations; Cues; Data; Data Analyses; Development; Enrollment; Exposure to; Family; Future; Goals; Grant; Health; Heart Rate; Hormones; Impaired cognition; Impairment; Incidence; Infant; Infant Behavior; Infant Development; Intervention; Intervention Studies; Longitudinal Studies; Mentored Research Scientist Development Award; Mentorship; Methodology; Methods; Mission; Mothers; Movement; National Institute of Child Health and Human Development; Nervous System Physiology; Outcome; Parents; Patient Self-Report; Pattern; Physiological; Physiology; Play; Polysomnography; Positioning Attribute; Process; Public Health; Questionnaires; Regulation; Research; Research Personnel; Research Project Grants; Resources; Respiration; Risk; Role; Science; Sleep; Stress; System; Temperature; Testing; Time; Training; Training Programs; Transact; Translating; Translational Research; Universities; Vulnerable Populations; Work; Writing; actigraphy; adverse outcome; aged; behavioral health; behavioral impairment; biobehavior; career; career development; child neglect; deprivation; diaries; early childhood; efficacious intervention; evidence base; experience; high risk parents; improved; indexing; infant outcome; intervention program; longitudinal design; maltreatment; neglect; novel; poor sleep; professor; responsible research conduct; sensor; skills; tenure track; therapy development

PROJECT SUMMARY/ ABSTRACT The proposed K01 award will provide a 5-year training program to support Dr. Brown's career goal of becoming an independent researcher in the fields of child maltreatment, developmental science, and sleep. The K01 study will take place at Colorado State University where Dr. Brown will begin a tenure-track Assistant Professor position in August 2018. Dr. Brown will build on her skills in child maltreatment, stress physiology, and behavioral health by engaging in the following training goals: (1) develop skills in the acquisition, scoring, analysis, and interpretation of sleep and autonomic nervous system (ANS) data; (2) develop skills in parent- infant dyadic assessment and data analysis; (3) enhance expertise in translational research with families with neglect to inform the development of a child welfare intervention focused on sleep and ANS regulatory processes; and (4) engage in career development activities through grant writing, lab management, training in the responsible conduct of research, mentorship, and dissemination of research findings. Dr. Brown will receive training from Dr. LeBourgeois, an expert in early childhood and family sleep; Dr. Fifer, an expert in the assessment of infant sleep and ANS functions; Dr. Lunkenheimer, an expert in co-regulation in parents and children exposed to maltreatment; and Dr. Taussig, an expert in translational intervention research with child welfare-involved children and families. Dr. Brown will receive consultation from Dr. Garrison who will offer expertise on child and family sleep intervention development; and Dr. Sharp, who will advise on dyadic data analysis. Research Project: Early physiological and behavioral co-regulation between parent and infant supports healthy infant development and family functioning. In families with neglect, this co-regulation manifests as discordance in regulatory biomarkers between parent and infant physiology and behavior, thereby placing families at risk for maladaptive outcomes. Sleep is another core regulatory process that may be implicated in neglect and is pivotal to infant development and family functioning. Yet, current understanding of parent-infant co-regulation of sleep is limited and critical to inform potential future interventions for neglectful families. The goal of this study is to build on the extant research on physiological and behavioral co-regulation of parent-infant dyads and address the following aims: (1) to identify longitudinal patterns of parent-infant co- regulation of sleep and ANS processes in families with and without neglect; and (2) to determine the extent to which co-regulation of sleep and ANS processes can distinguish adaptive from maladaptive parent-infant outcomes in families with and without neglect. Study methods will involve a longitudinal design with self-report, physiological, and behavioral assessments of 90 parents and their infants aged 6-9 months with and without neglect. The proposed activities will have a significant impact by elucidating sleep as a novel process in the study of parent-infant co-regulation and our understanding of how sleep and autonomic regulatory processes transact over time in order to provide improved targets for intervention among high-risk parent-infant dyads.

项目摘要/摘要 拟议的K01奖将提供一项为期5年的培训计划，以支持布朗博士的职业目标 成为儿童虐待，发展科学和睡眠领域的独立研究员。 K01研究将在科罗拉多州立大学举行，布朗博士将在那里开始终身助手 教授职位于2018年8月。布朗博士将以她在儿童虐待，压力生理学的技能为基础， 通过实现以下培训目标来和行为健康：（1）发展获取，评分， 分析和解释睡眠和自主神经系统（ANS）数据； （2）发展父母的技能 - 婴儿二元评估和数据分析； （3）增强与患有家庭的转化研究专业知识 忽略了为开发儿童福利干预的发展，该干预专注于睡眠和ANS监管 过程； （4）通过赠款写作，实验室管理，培训从事职业发展活动 负责任的研究，指导和研究结果的传播。布朗·威尔博士 接受童年和家庭睡眠专家Lebourgeois博士的培训； Fifer博士，专家 评估婴儿睡眠和ANS功能； Lunkenheimer博士，父母共同监管的专家 暴露于虐待的孩子； Taussig博士，与孩子的翻译干预研究专家 涉及福利的儿童和家庭。布朗博士将获得加里森博士的咨询，他将提供 儿童和家庭睡眠干预发展的专业知识；和夏普博士，他将为二元数据提供建议 分析。研究项目：父母与婴儿之间的早期生理和行为共同调节 支持健康的婴儿发育和家庭功能。在有忽视的家庭中，这种共同调节 表现为父母生理和行为之间的调节生物标志物的不一致，从而表现为 使家庭面临适应不良后果的风险。睡眠是另一个核心监管过程 与忽视有关，对婴儿的发展和家庭功能至关重要。然而，当前对 父母对睡眠的共同调节是有限的，至关重要 家庭。这项研究的目的是建立关于生理和行为共同调节的现有研究 父母的二元组并解决以下目的：（1）确定父母伴侣的纵向模式 在有或没有忽视的家庭中对睡眠和ANS程序进行调节； （2）确定 哪些睡眠和ANS过程的共同调节可以区分适应性的适应性父母 有和没有忽视的家庭的结果。研究方法将涉及具有自我报告的纵向设计， 有或没有的，有或没有的，有或没有的，有或没有的，有或没有 忽视。提出的活动将通过将睡眠作为新过程中的新过程产生重大影响 研究父母的共同调节以及我们对睡眠和自主性调节过程的理解 随着时间的流逝，交易以提供改进的高风险父母侵入二元组的目标。