Skeletal Muscle: Development, Regeneration and Disease

骨骼肌：发育、再生和疾病

• 批准号: 10237575
• 负责人: Elizabeth H Chen
• 金额: $ 2万
• 依托单位: SOCIETY FOR MUSCLE BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-06 至 2022-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10237575
• 关键词: Address; Affect; Applications Grants; Area; Attention; Basic Science; Biology; Biomedical Engineering; Cell Therapy; Cells; Clinical; Collaborations; Communities; Country; Development; Disease; Disease model; Duchenne muscular dystrophy; Emerging Technologies; Ensure; Epigenetic Process; Extracellular Matrix; Facioscapulohumeral; Faculty; Fertilization; Fostering; Generations; Genetic; Genetic Transcription; Geography; Goals; Growth; Human; International; Italy; Lead; Malignant Neoplasms; Mentors; Minority; Modeling; Molecular and Cellular Biology; Muscle; Muscle Development; Muscle satellite cell; Muscular Dystrophies; Myoblasts; Myopathy; Natural regeneration; Policies; Postdoctoral Fellow; Regulation; Research; Research Personnel; Rhabdomyosarcoma; Science; Scientist; Series; Skeletal Muscle; Slide; Societies; Students; Therapeutic; Tissue Model; Tissues; Translating; Translational Research; Woman; Work; career development; career networking; diversity and inclusion; doctoral student; epigenetic regulation; experience; frontier; gene therapy; graduate student; human disease; induced pluripotent stem cell; malignant muscle neoplasm; meetings; metabolic abnormality assessment; molecular dynamics; muscle metabolism; muscle regeneration; myogenesis; novel; novel strategies; novel therapeutics; posters; professor; programs; repaired; symposium; therapy development; tissue repair; unpublished works

SUMMARY The goal of the “Skeletal muscle: development, regeneration and disease” conference is to bring together international leaders in skeletal muscle research to provide a forum for cutting edge genetic, cellular and molecular biology underlying muscle development, regeneration and disease. This Frontiers in Myogenesis series organized by the Society for Muscle Biology has been held every three years for the last twenty years and has successfully defined the state of the art in the field. The 2021 meeting will not only discuss recent discoveries in skeletal muscle development and repair, but will also encompass advances in our understanding of human diseases, including muscular dystrophies and cancer. Our keynote speaker will be Dr. Eric Olson, who has performed exceptional work in muscle development and developed therapeutic strategies for treating Duchenne muscular dystrophy. Eleven plenary sessions are planned to address the following topics: cellular and molecular dynamics of skeletal muscle development, myoblast fusion and muscle growth, muscle stem cell regulation, epigenetic regulation of skeletal muscle, iPS cells, bioengineering and emerging technologies to study and repair skeletal muscle, muscle metabolism and cancer, muscle tissue and disease models, microenvironment in skeletal muscle repair and disease, muscle disease mechanisms, and translating skeletal muscle science into new therapies. Invited speakers (36) have been selected for their scientific excellence, with particular attention to appropriate representation (42% women/minorities) and geographical diversity (39% are from non-US countries). In addition, 19 short talks will be selected from submitted abstracts to provide opportunities for postdocs and students to present their work. Speakers are explicitly required to talk about unpublished work, to ensure scientific discussions focused at the forefront of the field. In addition, we will have three poster sessions each accompanied by a “posters blitz” where poster presenters will give a 1-minute talk to highlight/advertise their work. To further foster interaction, we will organize lunch sessions so that speakers are evenly distributed and attendees can sign up to join their table. Finally, we have included two professional development sessions to discuss grant application, as well as diversity and inclusion in science. This Conference will provide a forum for discussing recent discoveries in skeletal muscle research, and foster cross-fertilization among investigators from diverse areas and backgrounds, to further advance our understanding of muscle biology and facilitate the development of translational efforts for potential therapies for muscle diseases.

概括 “骨骼肌：发展，再生和疾病”会议的目标是结合在一起 骨骼肌研究领域的国际领导者为尖端遗传，细胞和 分子生物学的肌肉发育，再生和疾病。肌发生的边界 在过去的二十年中，由肌肉生物学协会组织的系列每三年举行一次 成功定义了该领域的艺术状况。 2021会议不仅会讨论最近的发现 在骨骼肌肉发育和修复方面，但也将涵盖我们对人类的理解的进步 疾病，包括肌肉营养不良和癌症。我们的主题演讲者将是埃里克·奥尔森（Eric Olson）博士 在肌肉发育和制定了治疗Duchenne方面开发了出色的工作 肌肉营养不良。计划进行11个全体会议，以解决以下主题：细胞和分子 骨骼肌发育，肌细胞融合和肌肉生长的动力学，肌肉干细胞调节， 研究和修复的骨骼肌，IPS细胞，生物工程和新兴技术的表观遗传调节 骨骼肌，肌肉代谢和癌症，肌肉组织和疾病模型，微环境 骨骼肌修复和疾病，肌肉疾病机制以及将骨骼肌科学转化为 新疗法。被邀请的演讲者（36）被选为其科学卓越的选择，特别关注 适当的代表（42％的妇女/少数民族）和地理多样性（39％来自非美国 国家）。此外，将从提交的摘要中选出19次简短谈判，以提供机会 博士后和学生介绍他们的作品。说话者明确要求谈论未发表的作品， 确保科学讨论集中在该领域的最前沿。此外，我们将举行三个海报会议 每个伴随着“海报闪电战”，海报演讲者将进行1分钟的演讲以突出/广告 他们的工作。为了进一步促进互动，我们将组织午餐会议，以便扬声器均匀分发 与会者可以注册以加入他们的桌子。最后，我们包括了两个专业发展会议 讨论赠款的应用，以及科学中的多样性和包容性。这次会议将提供一个论坛 讨论骨骼肌研究中的最新发现以及研究人员之间的互交杂种 从潜水区和背景，进一步提高我们对肌肉生物学的理解并促进 开发用于肌肉疾病潜在疗法的翻译努力。