Development of Spatial Transcriptomics Capability

空间转录组学能力的发展

• 批准号: 10582415
• 负责人: Robert E. Lewis
• 金额: $ 25万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-03-16 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10582415
• 关键词: Address; Applications Grants; Biological; Career Mobility; Centers of Research Excellence; Complex; Data Set; Detection; Development; Disease; Drug Targeting; Faculty; Funding; Gene Expression; Generations; Goals; Health; Human; Medical center; Mission; Molecular Target; Nebraska; Organ; Paper; Publications; Research; Research Personnel; Research Project Grants; Resources; System; Tissues; Universities; complex data; cost; new technology; tool; transcriptomics; Address; Applications Grants; Biological; Career Mobility; Centers of Research Excellence; Complex; Data Set; Detection; Development; Disease; Drug Targeting; Faculty; Funding; Gene Expression; Generations; Goals; Health; Human; Medical center; Mission; Molecular Target; Nebraska; Organ; Paper; Publications; Research; Research Personnel; Research Project Grants; Resources; System; Tissues; Universities; complex data; cost; new technology; tool; transcriptomics

The goals of the Nebraska Center for Molecular Target Discovery and Development (CMTDD) are to (1) provide the means necessary to define, validate, and develop potential therapies against disease targets, and (2) facilitate the professional and scientific development of early-stage investigators. Consistent with the scope of the CMTDD mission, the aim of this supplemental request is to purchase a MERSCOPE (Vizgen, Inc.) and provide spatial transcriptomics capability to early-stage investigators of the Nebraska Center for Molecular Target Discovery and Development (CMTDD) and other COBREs in the University system. MERSCOPE will be a cornerstone of the CMTDD omics resource, which will lower the cost barrier for investigators whose research papers and grant applications would benefit from the generation and analysis of complex data sets.

内布拉斯加州分子目标发现与发展中心（CMTDD）的目标是（1） 提供定义，验证和开发针对疾病靶标的潜在疗法的必要手段，以及 （2）促进早期研究人员的专业和科学发展。与范围一致 在CMTDD任务中，此补充请求的目的是购买Merscope（Vizgen，Inc。）和 为内布拉斯加州分子中心的早期研究者提供空间转录组学的能力 目标发现与发展（CMTDD）和大学系统中的其他Cobres。 Merscope会 成为CMTDD OMICS资源的基石，该资源将降低调查人员的成本障碍 研究论文和赠款应用程序将受益于复杂数据集的生成和分析。