Administrative Core

行政核心

基本信息

批准号：
10559477
负责人：
Quan Lu
金额：
$ 16.57万
依托单位：
HARVARD SCHOOL OF PUBLIC HEALTH
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-02-21 至 2025-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10559477
关键词：
Administrator Advisory Committees Animals Climate Cognition Cognitive Cognitive aging Collaborations Communication Complex Mixtures Computational Science Data Data Science Decision Making Detection Elderly Emergency response Ensure Environmental Engineering technology Environmental Epidemiology Environmental Health Environmental Protection Environmental Science Faculty Fostering Future Genetic Goals Government Agencies Hazardous Substances Health Human Information Dissemination Infrastructure Institution Institutional Review Boards Interdisciplinary Communication Interdisciplinary Study Leadership Life Massachusetts Mentors Metal exposure Metals Mission Modeling Molecular Genetics Molecular Toxicology Neurobiology Newsletter Policy Maker Postdoctoral Fellow Public Health Public Health Schools Research Research Personnel Research Project Grants Resource Sharing Resources Risk Science Scientist Series Source Superfund Technology Technology Transfer Time Toxicology Training Translating Translational Research United States National Institutes of Health Universities Visit Work community center data sharing design direct application early life exposure global environment graduate student human subject human subject protection improved insight meetings member multidisciplinary podcast programs remediation social media superfund site symposium technology development tool translational approach translational potential web site working group

项目摘要

SUMMARY/ ABSTRACT As the hub of our Superfund Research Center (SRC), the Administrative Core will advance our mission—to understand and mitigate the effects of exposures to metals and metal mixtures found at Superfund sites on late-life cognitive health—by providing executive oversight of all SRC activities, from scientific to fiscal to logistical to research translation. Based in the Department of Environmental Health at the Harvard T.H. Chan School of Public Health, the Administrative Core will comprise a Director (Dr. Quan Lu), Deputy Director (Dr. Julie Zimmerman of Yale University), Research Translation Coordinator (Dr. Katherine von Stackelberg), and Center Administrator and will be guided by an Executive Committee (comprising Project and Core Leaders) and an External Advisory Committee. The Core will provide leadership and coordination to ensure that all Research Project and Core activities align with the Superfund Research Program mandates and Superfund mission “to solve target problem(s) related to health effects, risk, detection, and/or remediation of hazardous substances.” The Administrative Core has four Specific Aims. In Aim 1, we will organize and coordinate intra- Center meetings and conferences, including regular seminars, monthly meetings with an Executive Committee, and yearly meetings with the External Advisory Committee (8 members, including subject matter experts and stakeholders). In Aim 2, we will organize seminars and meetings to serve as central integration for all members of the SRC community—professionals who bring diverse expertise in environmental epidemiology, genetics, molecular toxicology, environmental science and engineering, and computational and data science— to foster interactions that will strengthen existing collaborations, generate new ideas for future cross- disciplinary collaborations, and provide interdisciplinary research and translation opportunities for trainees. In Aim 3, we will provide central administration, fiscal management, and quality management to ensure research integrity, as well as compliance with NIH requirements for data and resource sharing and human and animal institutional review board requirements. In Aim 4 we will facilitate research translation through 1) effective communication within the SRC and with stakeholders, leveraging collaborations with regional SRCs (e.g., the Northeast regional Superfund trainee conference and the Complex Mixtures working group); 2) partnerships with government agencies, including a visiting scientist program with EPA; 3) technology transfer in conjunction with the Harvard Office of Technology Development and Yale Entrepreneurial Institute, and 4) information dissemination to broad audiences through channels including social media, newsletters, podcasts and videos. By providing an infrastructure that facilitates communication and integration across all Center components, the Administrative Core ensures effective integration of the SRC to better understand how early life exposures to metals influence later life cognition, potential remediation strategies in reducing risks, and the overall impact on public health.

摘要/摘要作为我们超级基金研究中心 (SRC) 的枢纽，行政核心将推进我们的使命—— 了解并减轻超级基金网站上发现的金属和金属混合物暴露的影响晚年认知健康——通过对所有 SRC 活动（从科学到财务到哈佛大学 T.H. Chan 环境健康系的后勤研究翻译。公共卫生学院，行政核心将由主任（鲁泉博士）、副主任（吕泉博士）组成。耶鲁大学的 Julie Zimmerman）、研究翻译协调员（Katherine von Stackelberg 博士）和中心管理员，并由执行委员会（包括项目和核心领导者）指导核心将提供领导和协调，以确保所有研究项目和核心活动符合超级基金研究计划的任务和超级基金使命“解决与健康影响、风险、检测和/或补救危险相关的目标问题” 行政核心有四个具体目标，在目标 1 中，我们将组织和协调内部。中心会议，包括定期研讨会、每月与执行委员会举行的会议，与外部咨询委员会（8 名成员，包括主题专家和在目标 2 中，我们将组织研讨会和会议，作为所有人的中心整合 SRC 社区的成员——在环境流行病学方面带来不同专业知识的专业人士，遗传学、分子毒理学、环境科学与工程、计算与数据科学—— 促进互动，加强现有合作，为未来的跨界合作产生新想法学科合作，并为学员提供跨学科研究和翻译机会。目标 3，我们将提供中央管理、财务管理和质量管理，以确保研究完整性，以及遵守 NIH 对数据和资源共享以及人类和动物的要求在目标 4 中，我们将通过 1) 有效促进研究成果转化。 SRC 内部以及与利益相关者的沟通，利用与区域 SRC 的合作（例如，东北地区超级基金实习生会议和复杂混合物工作组）2）伙伴关系；与政府机构合作，包括与 EPA 的访问科学家计划 3) 与哈佛技术开发办公室和耶鲁创业学院合作，以及 4) 通过社交媒体、时事通讯、播客等渠道向广大受众传播信息通过提供促进整个中心的沟通和集成的基础设施。组件，管理核心确保 SRC 的有效集成，以更好地了解如何尽早生活中接触金属会影响以后的认知、降低风险的潜在补救策略以及对公共卫生的总体影响。