Administrative Core

行政核心

基本信息

批准号：
10406866
负责人：
Mary Sano
金额：
$ 62.96万
依托单位：
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-05-01 至 2025-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10406866
关键词：
Accountability Address Administrator Advisory Committees Alzheimer disease prevention Alzheimer&apos s Disease Animals Applied Research Budgets Calendar Clinical Collaborations Communication Communities Data Data Collection Dementia Detection Development Diagnosis Diagnostic Disease Education Ensure Evaluation Event Faculty Faculty Recruitment Fostering Funding Funding Agency Goals Health Insurance Portability and Accountability Act Health system Heterogeneity Infrastructure Institution International Knowledge Leadership Location Mentors Mission Monitor Performance Process Productivity Regulation Research Research Personnel Resources Sampling Science Structure Technology Therapeutic Time Translational Research cell repository cohort comorbidity disease heterogeneity education research human subject improved knowledge of results medical schools meetings outreach programs recruit resilience resource guides sample collection success

项目摘要

Mount Sinai ADRC (Sano): Administrative Core (Core A) – Research Summary The Administrative Core of the MSADRC provides leadership to manage and coordinate the research agenda for the MSADRC to ensure success in our mission to “Understand disease heterogeneity to optimize therapeutic approaches to treat and cure Alzheimer's disease”. The overall aims are as follows. 1) To provide leadership and an operational infrastructure to facilitate communication among cores, and with national entities including NIA program staff, National Alzheimer's Disease Coordinating Center (NACC) and the National Cell Repository for Alzheimer's Disease (NCRAD). The structure includes an Executive Committee (EC) an External Advisory Committee (EAC), and an Internal Advisory Committee. The Core also maintains administrative, financial and regulatory oversight. 2) To ensure that the MSADRC addresses the agenda of the National Alzheimer's Project Act (NAPA). 3) To create a program that supports developmental projects that will stimulate Alzheimer's disease (AD) research around the institution. 4) To evaluate all activities to ensure they generate the planned resources and disseminate them broadly, and to optimize their impact on finding a cure for AD. The Administrative Core oversees activities across two locations, the Icahn School of Medicine at Mount Sinai (ISMMS) and the James J Peters VAMC. Through a clear structure for governance, with a set of advisory and working committees, and a calendar of meetings with prescribed agendas, the Administrative Core assures coordinated interaction among the Directors and the Core Leaders. The Administrative Core assures that the recruitment and retention of a diverse cohort, the data and sample collection, and data distribution all occur in a timely manner. It assists the Research Education Component in its task to identify AD Scholars successfully, enrich their education through mentoring from all of the MSADRC Core Leaders and enhance their research opportunities using resources provided by the Cores. This is achieved through regular meetings with all Core staff to address operational issues and to foster collaboration across MSADRC faculty, and with other AD researchers within ISMMS and beyond. The Administrative Core guarantees that data and samples are provided to NACC and NCRAD in a timely manner; it is responsible for communicating with the funding agency, the NIA Center program leaders and staff, to promote dissemination of research findings and opportunities to the widest community. The Core administrator oversees fiscal and regulatory issues, guaranteeing compliance with guidance for human subject and animal protection, organizes the annual call for Developmental Projects including preparing and disseminating a call for proposals and organizing a scientific review under the leadership of the MSADRC Director and Associate Directors. The administrator also assists with tracking evaluations of core performance, REC success, productivity of Developmental Projects, and faculty recruitment and promotion. !

西奈山ADRC（SANO）：行政核心（核心A） - 研究摘要 MSADRC的行政核心提供了管理和协调研究议程的领导使MSADRC确保我们的任务成功，以“了解疾病异质性以优化治疗和治愈阿尔茨海默氏病的治疗方法”。总体目的如下。1）领导和运营基础设施，以托管核心之间的沟通，以及与国家实体之间的沟通包括NIA计划工作人员，国家阿尔茨海默氏病协调中心（NACC）和国家牢房阿尔茨海默氏病的存储库（NCRAD）。该结构包括执行委员会（EC）外部咨询委员会（EAC）和内部咨询委员会。核心也坚持行政，财务和监管监督。 2）确保MSADRC解决了国家阿尔茨海默氏症计划法（NAPA）。 3）创建一个支持开发项目的程序将刺激该机构周围的阿尔茨海默氏病（AD）研究。 4）评估所有活动以确保他们生成计划的资源并广泛传播它们，并优化其对寻找一个的影响治愈广告。行政核心监督两个地点的活动，即伊坎医学院西奈山（ISMMS）和詹姆斯·J·彼得斯·瓦姆（James J Peters Vamc）。通过清晰的治理结构，一套咨询和工作委员会，以及与规定议程的会议日历，行政核心假设董事和核心领导者之间的交互作用。行政核心假设招募和保留多样的队列，数据和样本收集以及数据分配全部及时发生。它有助于研究教育部分确定广告学者们成功地通过所有MSADRC核心领导者的心理来丰富他们的教育使用核心提供的资源来增强他们的研究机会。这是通过常规的与所有核心员工的会议，以解决运营问题并促进MSADRC教职员工的合作，以及ISMM及其他地区的其他广告研究人员。行政核心保证数据和及时向NACC和NCRAD提供样品；它负责与 NIA中心计划的负责人和员工资助机构，以促进研究结果的传播最广泛的社区的机会。核心管理员监督财政和监管问题，保证遵守人类对象和动物保护指南，组织年度呼吁发展项目，包括准备和传播提案的呼吁和组织科学在MSADRC董事和副董事的领导下进行审查。管理员还协助通过跟踪评估核心绩效，REC成功，发展项目的生产力以及教师招募和晋升。呢