Core A: Administrative Core

核心A：行政核心

• 批准号: 10588795
• 负责人: Carol Fuzeti Elias
• 金额: $ 16.15万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-02-01 至 2028-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10588795
• 关键词: Administrator; Advertisements; Advisory Committees; Animals; Biotechnology; Budgets; Charge; Communication; Complex; Contracts; Counseling; Data; Data Analyses; Databases; Development; Diabetes Mellitus; Ensure; Equipment; Fee-for-Service Plans; Feedback; Funding; Germ-Free; Guidelines; Income; Institution; Laboratories; Leadership; Metabolic; Michigan; Modeling; Monitor; Mus; National Institute of Diabetes and Digestive and Kidney Diseases; Obesity; Phenotype; Physiological; Preparation; Principal Investigator; Procedures; Progress Reports; Protocols documentation; Quality Control; Records; Recovery; Reporting; Research; Research Personnel; Resources; Schedule; Secure; Services; Standardization; Technology; Training; Universities; Work; animal care; behavioral phenotyping; cost; data submission; experience; meetings; metabolic phenotype; nutrition; programs; synergism; web site

Abstract/Summary – Administrative Core The Administrative Core will be responsible for the overall leadership and scientific oversight of the Michigan Metabolic Phenotyping of live Models of Obesity and Diabetes (Mi-MPMOD) Center. The Core will provide administrative assistance to the Animal Care and Germ-Free Core and the Metabolic, Physiological and Behavioral (MPB) Phenotyping Core and ensure that their services are delivered efficiently and to the highest possible standards. The leadership team has extensive administrative experience and is centrally located in the North Campus Research Complex at the Elizabeth W. Caswell Diabetes Institute (CDI), adjacent to administrative cores of the Michigan Diabetes Research Center (MDRC), the Michigan Nutrition and Obesity Research Center (MNORC) and the CDI. This clustering of related Administrative Cores facilitates an efficient use of space and equipment and leverages the collective experience of all centers’ administrators assuring the transfer of best practices among them. The administrative core will: a) Coordinate the receipt of animals and assignments for the appropriate phenotyping services; b) monitor studies progress until completion of data analysis and submission of final reports to the requesting investigator(s); c) ensure secure processing and signing of all necessary conditions of use statements, contracts, service fees, and data records as well as the subsequent data submission to the MPMOD Consortium and Coordinating Unit (CU) database; d) manage budgetary and workflow records, oversee cost recovery, program income and adjustment of service charges; e) re-budget Center funds based on the cores service activity and scientific needs; f) promote the availability of MPMOD resources to local investigators, regional partners, and nationwide research institutions, including academic and for-profit biotechnology and pharma companies; g) develop communication strategies to specifically target underrepresented PIs and small laboratories or institutions that have not received significant federal research funding through advertisement, seminars, and direct contact with the academic departments; h) facilitate the development of new research technology and training resources for the Center’s MPB Phenotyping Core; and i) meet regularly with the Advisory committees and oversee the preparation and submission of annual progress report to NIDDK. The Administrative Core will work closely with the Centers’ Consortium and the national CU by actively participating in the solicitation and review of applications for the MPMOD Consortium’s funding programs. It will also work in synergy with the Consortium and CU to minimize overlap of services and establish, standardize, document, and distribute phenotyping protocols and quality control procedures to laboratories nationwide.

摘要/总结 – 行政核心 行政核心将负责密歇根州的总体领导和科学监督 肥胖和糖尿病活体模型的代谢表型分析 (Mi-MPMOD) 中心将提供。 对动物护理和无菌核心以及代谢、生理和 行为 (MPB) 表型核心并确保他们的服务高效交付并达到最高水平 领导团队拥有丰富的管理经验，并且集中在 伊丽莎白·卡斯韦尔糖尿病研究所 (CDI) 的北校区​​研究中心，毗邻 密歇根糖尿病研究中心 (MDRC)、密歇根营养与肥胖中心的行政核心 研究中心 (MNORC) 和 CDI 的相关管理核心的聚集促进了高效的工作。 空间和设备的使用，并利用所有中心管理员的集体经验，确保 行政核心将： a) 协调动物的接收和 分配适当的表型分析服务；b) 监测研究进展直至数据完成 分析并向提出请求的研究者提交最终报告； c) 确保安全处理和 签署所有必要的使用条件声明、合同、服务费和数据记录以及 随后将数据提交给 MPMOD 联盟和协调单位 (CU) 数据库 d) 管理； 预算和工作流程记录，监督成本回收、计划收入和服务费调整； e) 根据核心服务活动和科学需求重新调整中心资金预算； MPMOD 向当地研究人员、区域合作伙伴和全国研究机构提供的资源，包括 学术和营利性生物技术和制药公司； g) 制定沟通策略 特别针对代表性不足的 PI 以及尚未获得重大成果的小型实验室或机构 通过广告、研讨会和与学术部门的直接联系获得联邦研究经费； h) 促进中心MPB新研究技术和培训资源的开发 表型核心；和 i) 定期与咨询委员会会面并监督准备工作和 向 NIDDK 提交年度进度报告 行政核心将与中心密切合作。 联合体和国家CU积极参与申请的征集和审查 MPMOD 联盟的资助计划还将与联盟和 CU 协同工作，以尽量减少。 服务重叠并建立、标准化、记录和分发表型分析方案和质量 全国实验室的控制程序。