Proactive Management to Improve Laboratory Macaque Breeding Colony Health and Well-being

积极管理以改善实验室猕猴繁育群体的健康和福祉

基本信息

批准号：
10090056
负责人：
Brenda McCowan
金额：
$ 75.79万
依托单位：
UNIVERSITY OF CALIFORNIA AT DAVIS
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-06-15 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10090056
关键词：
Acute Address Adopted Adult Aggressive behavior Animals Biological Markers Breeding Cardiovascular system Choices and Control Chronic stress Communities Cost Savings Development Disease Outbreaks Economic Burden Economics Environmental Monitoring Event Excision Food Funding Health Health Promotion Hospitalization Housing Human Immune Individual Industry Intervention Investigation Laboratories Lead Location Macaca Macaca mulatta Measures Metabolic Methodology Methods Modeling Monoclonal Antibody R24 Neurosecretory Systems Pathway Analysis Personal Satisfaction Personality Physiological Primates Procedures Process Research Resources Rhesus Scheme Series Signal Transduction Social Controls Social Network Stress Stressful Event Structure System Techniques Testing Time Trauma Treatment Efficacy United States National Institutes of Health Visual War allostatic load arm base cohesion cost cost effective design expectation experimental study feeding food resource health assessment improved male member nonhuman primate novel physical conditioning preference prevent programs social social group welfare

项目摘要

Project Summary This study will advance the current understanding of how management procedures that involve predictability, opportunity and control can be implemented proactively to accomplish meaningful reductions in stress, social aggression and trauma that generate a net cost savings for the CNPRC (and other primate facilities). Our investigation of social network structure and dynamics using novel network measures and techniques will allow us to gain a deeper understanding of whether/how these management strategies accomplish such reductions in stress and trauma, such as offering methodologies for examining the complexity of social stability, and our utilization of a thorough economic approach to calculate all costs associated with implementation of management procedures will allow us to conclude with certainty which management strategies reduce hospitalizations due to stress and trauma with minimal increases in staff time to yield significant cost savings for the CNPRC (and other primate facilities), and ultimately improve animal health and well-being in a cost- effective fashion.

项目概要这项研究将增进目前对涉及可预测性的管理程序如何、可以主动实施机会和控制，以有意义地减少压力、社交攻击和创伤为 CNPRC（和其他灵长类动物设施）带来净成本节省。我们的使用新颖的网络措施和技术对社交网络结构和动态进行调查将允许我们更深入地了解这些管理策略是否/如何实现此类减少在压力和创伤方面，例如提供检查社会稳定复杂性的方法，以及我们的利用彻底的经济方法来计算与实施相关的所有成本管理程序将使我们能够确定哪些管理策略可以减少因压力和创伤而住院，只需增加最少的工作人员时间即可显着节省成本为 CNPRC（和其他灵长类动物设施）提供服务，并最终以较低的成本改善动物健康和福祉有效的时尚。