Hispanic Alliance for Clinical and Translational Research (Alliance)

西班牙裔临床和转化研究联盟（联盟）

• 批准号: 10252021
• 负责人: MARCIA Roxana CRUZ-CORREA
• 金额: $ 300万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-02 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10252021
• 关键词: Academia; Address; Adoption; Affect; Bioinformatics; Biometry; Cardiometabolic Disease; Clinical; Clinical Research; Collaborations; Communicable Diseases; Communication; Communities; Community Health; Community Networks; Community Outreach; Development; Development Plans; Disasters; Disease; Emerging Communicable Diseases; Ensure; Epidemiology; Evaluation; Foundations; Funding; Generations; Goals; Government; Health; Health Policy; Health Sciences; Healthcare; Hispanics; Human Resources; Infrastructure; Institution; Island; Knowledge; Laboratories; Lead; Leadership; Malignant Neoplasms; Medical; Mentors; Methods; Mission; Modeling; Outcome; Participant; Pilot Projects; Population; Positioning Attribute; Process; Public Health; Puerto Rico; Research; Research Design; Research Personnel; Resources; Safety; Science; Scientist; Services; Specific qualifier value; Structure; Subgroup; System; Technology; Training; Training Activity; Training Support; Translational Research; United States; United States National Institutes of Health; Universities; Work; base; biomedical informatics; career development; community based participatory research; community center; community engagement; cyber infrastructure; data infrastructure; data warehouse; effective therapy; epidemiology study; health care delivery; health data; improved; innovation; interdisciplinary collaboration; medical schools; medically underserved; next generation; programs; recruit; research and development; research facility; statistics; translational research program

Improving health care for the medically underserved, including our Hispanic population, afflicted by prevalent diseases, such as cancer, cardio-metabolic and infectious diseases, remains a major challenge. The current application is to support the development of Hispanic Alliance for Clinical & Translational Research in Puerto Rico (Alliance), which aims to build on the existing infrastructure of the Puerto Rico Clinical and Translational Research Consortia (PR-CTRC an RCMI-CTR) and the unique expertise on emerging infectious diseases and the study of disaster-related conditions and their impact on Health. The objective of the Alliance is to serve as the catalytic center to enhance the competitiveness of investigators to conduct research and obtain additional funding for clinical and translational research addressing highly prevalent diseases and those that affect the medically underserved in Puerto Rico. The long-term goal of the Alliance is to transform clinical and translational research in Hispanic populations in the Mainland and in Puerto Rico by promoting inter-disciplinary collaboration and leverage of resources to address diseases affecting Hispanic communities. Successful implementation of the Alliance will advance our fundamental knowledge of Hispanic health in this ethnic subgroup, which is increasingly represented in the U.S. mainland population. The Alliance is innovative because it will: (1) create a Hispanic-centered research hub integrating resources to support researchers in PR and national partners; (2) implement the Hispanic Real World clinical research data warehouse; and (3) establish a Community Health & Research Council comprised of diverse community partners emphasizing a community-centered, bi-directional research focus to impact health policy and ultimately improving health outcomes in our Hispanic community. The Alliance overall aims are specified below. Specific Aim 1: Enhance an island-wide infrastructure and human resource network and synergize with local and national partners to conduct clinical and translational research in Puerto Rico. Specific Aim 2: Provide professional development activities to enhance the ability of investigators to develop competitive clinical and translational research programs with emphasis on Hispanic health needs. Specific Aim 3: Facilitate the generation and dissemination of knowledge to and from the bench and the community to improve health outcomes that affect Hispanic communities in Puerto Rico and across United States. Specific Aim 4: Catalyze and sustain the integration of trans/multi/inter disciplinary collaborations to conduct clinical and translational research within and across institutions, organizations, community networks and health programs in Puerto Rico and other IDeA states.

改善医疗服务不足的医疗保健，包括我们的西班牙裔人口 普遍的疾病，例如癌症，心替代疾病和传染病，仍然是一个主要挑战。 当前的申请是支持临床和转化研究的西班牙裔联盟的发展 在波多黎各（联盟）中，旨在以波多黎各临床的现有基础设施为基础 转化研究联盟（PR-CTRC和RCMI-CTR）和有关新兴传染性的独特专业知识 疾病和与灾害有关的疾病及其对健康的影响。联盟的目标 作为催化中心，以增强研究人员进行研究和 获得额外的资金用于临床和转化研究，以解决高度普遍的疾病和 那些影响波多黎各的医学欠缺的人。联盟的长期目标是 改变大陆西班牙裔人口和波多黎各的临床和转化研究 促进跨学科的合作和资源杠杆作用，以解决影响影响的疾病 西班牙裔社区。 成功实施联盟将提高我们对西班牙裔健康的基本知识 在这个种族亚群中，在美国大陆人口越来越多地代表。联盟是 创新性是因为它将：（1）创建一个以西班牙裔为中心的研究中心，以整合资源来支持 公关和国家合作伙伴的研究人员； （2）实施西班牙裔现实世界临床研究数据 仓库; （3）建立一个由不同社区组成的社区健康与研究委员会 合作伙伴强调以社区为中心的双向研究重点，以影响卫生政策和 最终改善了我们西班牙裔社区的健康状况。联盟总体目标已指定 以下。 特定目的1：增强整个岛屿范围的基础设施和人力资源网络，并与本地协同作用 和国家合作伙伴在波多黎各进行临床和转化研究。 特定目标2：提供专业发展活动，以增强研究人员的发展能力 竞争性临床和转化研究计划，重点是西班牙裔健康需求。 特定目的3：促进往返于板凳的知识的产生和传播 社区改善影响波多黎各和整个曼联的西班牙裔社区的健康成果 国家。 特定目的4：催化和维持反式/多/跨学科合作的整合以进行 机构，组织，社区网络和卫生的临床和转化研究 波多黎各和其他思想状态的计划。