Mitral Valve Repair System to Percutaneously Treat Moderate to Severe Regurgitation Using Alfieri Edge-to-Edge Technique

二尖瓣修复系统使用 Alfieri 边缘对边缘技术经皮治疗中度至重度反流

• 批准号: 10258797
• 负责人: Raghuveer Basude
• 金额: $ 133.17万
• 依托单位: MEDFREE, INC.
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-01-02 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10258797
• 关键词: Acute; Address; Affect; Anastomosis - action; Animals; Blood Vessels; Catheters; Chronic; Clinic; Clinical; Corrosion; Data; Devices; Diagnosis; Evaluation; Exhibits; Family suidae; Fatigue; Feasibility Studies; Femoral vein; Government; Heart; Heart Atrium; Human; Implant; In Vitro; Institutional Review Boards; Intervention; Intuition; Mitral Valve; Mitral Valve Insufficiency; Modeling; Operative Surgical Procedures; Patients; Periodicity; Persons; Phase; Polyesters; Population; Preparation; Procedures; Process; Protocols documentation; Quality Control; Reporting; Research Design; Risk; Safety; Small Business Innovation Research Grant; Sterility; Structure; System; Techniques; Testing; Textiles; Thoracotomy; Time; Tissues; Training; Transesophageal Echocardiography; Tricuspid valve structure; United States; arm; base; cohort; commercialization; design; experimental study; first-in-human; grasp; healing; high risk; implant design; implantable device; implantation; improved; in silico; in vivo; innovation; porcine model; programs; public health relevance; repaired; response; success

The MEDFREE® Valve Repair System will innovatively improve upon the current market leading MitraClip device, while leveraging and building on the proven percutaneous Alfieri edge-to-edge repair technique. We aim to address this vastly unmet percutaneous structural heart market by delivering a simpler, easier-to-use device in a smaller 12 Fr catheter system that can be used by a single operator.

MEDFREE®阀维修系统将在当前市场领先的Mitraclip上进行创新改善 设备，同时利用并建立在经过验证的经皮的Alfieri边缘到边缘维修技术上。我们 旨在通过提供更简单，更易于使用的方式来解决这种极大的经皮结构心脏市场 单个操作员可以使用的较小12 fr导管系统中的设备。