Mitral Valve Repair System to Percutaneously Treat Moderate to Severe Regurgitation Using Alfieri Edge-to-Edge Technique

二尖瓣修复系统使用 Alfieri 边缘对边缘技术经皮治疗中度至重度反流

• 批准号: 10087432
• 负责人: Raghuveer Basude
• 金额: $ 5.5万
• 依托单位: MEDFREE, INC.
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-01-02 至 2020-10-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10087432
• 关键词: Acute; Address; Affect; Anastomosis - action; Anatomic Models; Anatomy; Catheters; Chronic; Clinical; Corrosion; Data; Device Designs; Devices; Evaluation; FDA approved; Fatigue; Femoral vein; Finite Element Analysis; Goals; Government; Heart; Heart Atrium; Hemorrhage; Human; Implant; Intervention; Methods; Mitral Valve; Mitral Valve Insufficiency; Modeling; Operative Surgical Procedures; Patients; Persons; Phase; Polyesters; Population; Procedures; Risk; Safety; Site; Small Business Innovation Research Grant; Stainless Steel; Structure; System; Techniques; Testing; Textiles; Thoracotomy; Time; Tissues; Training; United States; base; experience; grasp; healing; high risk; implantable device; implantation; improved; in silico; in vivo; innovation; pre-clinical; programs; prototype; public health relevance; repaired; response; success

The MEDFREE® Valve Repair System will innovatively improve upon the current market leading MitraClip device, while leveraging and building on the proven percutaneous Alfieri edge-to-edge repair technique. We aim to address this vastly unmet percutaneous structural heart market by delivering a simpler, easier-to-use device in a smaller 12 Fr catheter system that can be used by a single operator.

MEDFREE®阀维修系统将在当前市场领先的Mitraclip上进行创新改善 设备，同时利用并建立在经过验证的经皮的Alfieri边缘到边缘维修技术上。我们 旨在通过提供更简单，更易于使用的方式来解决这种极大的经皮结构心脏市场 单个操作员可以使用的较小12 fr导管系统中的设备。