Renewal of Delaware Center for Neuroscience Research

特拉华神经科学研究中心更新

• 批准号: 10254431
• 负责人: MELISSA A HARRINGTON
• 金额: $ 221.54万
• 依托单位: DELAWARE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-26 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10254431
• 关键词: Advisory Committees; Animal Model; Animals; Applications Grants; Award; Basic Science; Behavioral; Behavioral Research; Biomedical Engineering; Biomedical Research; Brain; Brain imaging; Centers of Research Excellence; Cognition; Collaborations; Communities; Data; Delaware; Development; Ensure; Environment; Faculty; Faculty Recruitment; Feeling; Functional Magnetic Resonance Imaging; Funding; Future Generations; Genetic; Goals; Grant; Heart; Human; Human Resources; Image; Infrastructure; Institution; Invertebrates; Investigation; Investments; Lead; Longevity; Magnetic Resonance Imaging; Maps; Memory; Mentored Research Scientist Development Award; Mentors; Minority; Modeling; Molecular; Neurosciences; Neurosciences Research; Pathologic; Phase; Pilot Projects; Program Development; Psychologist; Publications; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Research Training; Resources; Rodent; Rodent Model; Signal Transduction; Structure; Structure-Activity Relationship; Thinking; Time; Translational Research; United States National Institutes of Health; Universities; Work; base; bioimaging; career; community based participatory research; experience; faculty research; human subject; improved; innovation; instrumentation; inter-institutional; meetings; multidisciplinary; neuroimaging; non-invasive imaging; outreach; programs; relating to nervous system; success; symposium; training project; undergraduate research; undergraduate student; Advisory Committees; Animal Model; Animals; Applications Grants; Award; Basic Science; Behavioral; Behavioral Research; Biomedical Engineering; Biomedical Research; Brain; Brain imaging; Centers of Research Excellence; Cognition; Collaborations; Communities; Data; Delaware; Development; Ensure; Environment; Faculty; Faculty Recruitment; Feeling; Functional Magnetic Resonance Imaging; Funding; Future Generations; Genetic; Goals; Grant; Heart; Human; Human Resources; Image; Infrastructure; Institution; Invertebrates; Investigation; Investments; Lead; Longevity; Magnetic Resonance Imaging; Maps; Memory; Mentored Research Scientist Development Award; Mentors; Minority; Modeling; Molecular; Neurosciences; Neurosciences Research; Pathologic; Phase; Pilot Projects; Program Development; Psychologist; Publications; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Research Training; Resources; Rodent; Rodent Model; Signal Transduction; Structure; Structure-Activity Relationship; Thinking; Time; Translational Research; United States National Institutes of Health; Universities; Work; base; bioimaging; career; community based participatory research; experience; faculty research; human subject; improved; innovation; instrumentation; inter-institutional; meetings; multidisciplinary; neuroimaging; non-invasive imaging; outreach; programs; relating to nervous system; success; symposium; training project; undergraduate research; undergraduate student

Summary The Delaware Center for Neuroscience Research, established in 2012 with a phase I COBRE award, is a collaboration between Delaware State University (DSU) and the University of Delaware (UD) that uniquely brings together faculty and research resources from two very different institutions: a minority-serving, undergraduate university with an emerging strength in neuroscience research (DSU), and the state's flagship research university (UD). Phase I of the COBRE project was focused on supporting the research and professional development of a group of early stage investigators that included Project Leads, Pilot Grant PIs, and new faculty who were hired at DSU with COBRE support, and helping the investigators achieve grant success and scientific maturity. The program has been very successful with over 70 publications by COBRE-supported researchers, three Project Leads “graduated” into R01 support, a pilot investigator graduated to an NSF CAREER award, and two of the new faculty recruited to DSU with COBRE support winning K01 awards. Our phase II project will strengthen both our Center and neuroscience research in Delaware by catalyzing institutional investment in research infrastructure and continuing to grow the number of R01-competitive neuroscience researchers. Supporting our COBRE effort as we move to Phase II, UD has made a significant investment in the research infrastructure for neuroscience with the purchase of a 3T MRI scanner with the capability to map human brain activity, and the establishment of the Center for Biomedical and Brain Imaging. Our phase COBRE II award will catalyze additional investment in the purchase of a 7T, small bore magnet to expand the capabilities of the CBBI to include magnetic resonance imaging of rodent models. The overarching scientific goal of our Neuroscience Center is to bring together and support neuroscientists working at multiple scales, from human subjects to rodent and invertebrate models to improve our understanding of the dynamic function of the brain. During Phase II we will pursue three specific aims for our Center: 1) strengthening the research infrastructure and capacity in Delaware by fully developing the Center for Biomedical and Brain Imaging to include instrumentation and expertise for small animal MRI; 2) to further develop the interdisciplinary, inter-institutional Delaware Center for Neuroscience Research as a supportive scientific community focused on investigating dynamic structure- function relationships in the brain; and 3) to involve a new group of investigators in the Center's integrated mentoring and professional development program that helps junior faculty become independent, externally-funded researchers. Continuing this COBRE program will have two significant long-term benefits. First, we will continue to advance to our Delaware Center of Neuroscience Research to be a self-sustaining, and competitive research center that will advance our understanding of the brain and increase the amount of multidisciplinary biomedical and behavioral research carried out in Delaware. Second, the Center will support a group of early-stage faculty to become R01-funded investigators and advance to senior levels both academically and scientifically.

概括 特拉华州神经科学研究中心成立于2012年I阶段的圆锥 奖是特拉华州立大学（DSU）与特拉华大学（UD）之间的合作 这种独特的将教师和研究资源从两个截然不同的机构中汇集在一起​​： 少数派服务，本科大学，具有神经科学研究的新兴力量（DSU）， 以及该州的旗舰研究大学（UD）。 COBRE项目的第一阶段集中于 支持一组早期研究人员的研究和专业发展，其中包括 Project Leads，Pilot Grant PIS和新教师在DSU雇用了Cobre支持，并且 帮助调查人员取得成功和科学成熟。该程序非常 由Cobre支持的研究人员成功获得了70多个出版物，三个项目领导“毕业” 进入R01支持，一名飞行员调查员毕业于NSF职业奖，两名新教师 通过COBRE支持赢得K01奖，招募到DSU。我们的第二阶段项目将加强两者 我们在特拉华州的中心和神经科学研究通过催化研究机构投资 基础设施并继续增加R01竞争性神经科学研究人员的数量。 在我们进入第二阶段时，UD支持我们的鞋垫努力，对 通过购买3T MRI扫描仪的神经科学的研究基础设施，能够映射 人脑活动，以及生物医学和脑成像中心的建立。我们的阶段 COBRE II奖将促进购买7t，小孔磁铁的额外投资 扩展CBBI的功能，包括啮齿动物模型的磁共振成像。 我们神经科学中心的总体科学目标是结合并支持 从人类受试者到啮齿动物和无脊椎动物模型到多个尺度上工作的神经科学家 提高我们对大脑动态功能的理解。在第二阶段，我们将追求三个 对我们中心的具体目标：1）加强特拉华州的研究基础设施和能力 充分开发生物医学和脑成像中心，包括仪器和专业知识 用于小动物MRI； 2）进一步发展跨学科的，机构间特拉华州中心 神经科学研究作为一个支持科学界，致力于研究动态结构 - 大脑的功能关系； 3）让一组新的调查人员参与该中心的 有助于初级教师成为的综合心理和专业发展计划 独立的外部资助研究人员。继续这个毛绒计划将有两个重要的 长期利益。首先，我们将继续晋升为特拉华州神经科学研究中心 成为一个自我维持和竞争性的研究中心，将提高我们对大脑的理解 并增加在特拉华州进行的多学科生物医学和行为研究的数量。 其次，该中心将支持一群早期教师成为R01资助的调查员，并 准确和科学地晋升到高级水平。