Administrative Core

行政核心

• 批准号: 10244915
• 负责人: Hai Yao
• 金额: $ 55.64万
• 依托单位: CLEMSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-15 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10244915
• 关键词: Abbreviations; Advisory Committees; Animals; Award; Biomedical Engineering; Biomedical Research; Cadaver; Centers of Research Excellence; Clinic; Clinical; Communication; Computer Models; Computer Simulation; Data; Development; Devices; Discipline; Disease; Doctor of Philosophy; Engineering; Ensure; Evaluation; Extramural Activities; Faculty; Feedback; Glossary; Goals; Health; Health Resources; Health system; Human; Human Resources; Infrastructure; Joints; Knowledge; Leadership; Medical; Mentors; Methodology; Mission; Muscle; Musculoskeletal; Names; Natural regeneration; Outcome; Performance; Physicians; Pilot Projects; Process; Research; Research Personnel; Research Project Grants; Resources; Schools; Scientist; Services; South Carolina; Teacher Professional Development; Technology; Technology Transfer; Testing; Time; Tissues; Training; Translational Research; Trauma; Universities; acronyms; base; bone; design; experience; formative assessment; implantation; improved; improved functioning; in vivo; innovation; insight; malformation; meetings; member; multidisciplinary; novel strategies; organizational structure; pathogen; pre-clinical assessment; programs; sensor; sound; tool; virtual human

SUMMARY The mission of this ADMIN core is to be responsible for the leadership, integration and successful implementation of the COBRE for South Carolina Translational Research Improving Musculoskeletal Health (SC-TRIMH). The ADMIN Core director is Hai Yao, Ph.D. with Martine LaBerge, Ph.D. as Associate Director; Windsor Sherrill, PhD. and Michael Kern, Ph.D. complete the 4 member Executive Committee (EC). An Internal Advisory Committee of 9 senior institutional leaders and an External Advisory Committee of 3-5 eminent scientists will provide objective oversight, evaluation and strategic interactions to optimize the Center's impact. A Clinical Advisory Committee of 7 physicians will give insight into clinical problems that will focus junior investigator (JI) research, plus help advance innovation and give mechanistic understanding into translational/clinical benefits. The aims of the ADMIN Core are to: (1) Provide effective Leadership and Management to the SC-TRIMH, (2) Enhance Mentoring and Faculty Development by establishing a rigorous program that uses a “360° style” evaluation process to benefit both mentor and mentee, (3) Initiate a Pilot Projects Program with the SC-TRIMH themes to attract new and/or established investigators, enabling them to generate preliminary data via access to scientific cores, mentoring and all other programmatic resources with a goal of obtaining extramural competitive research awards, and (4) Develop and implement an integrated, long- term evaluation plan, with formative and summative methodologies, to assess the overall Center and its component parts. Innovative features of this ADMIN Core include: (1) Virtual Human Trials (VHT), bridging the gap between benchtop and clinics, via the iterative process of (i) computer simulation, (ii) device fabrication and/or sensor implantation, (iii) combined with in vivo assessment in animal or human cadavers. (2) Utilizing the strengths of engineering expertise, principles, and practices to achieve translational biomedical benefits. (3) Mentoring Team: each JI will have a primary and secondary mentor and all the SC-TRIMH members will be a resource to enhance and aid this mentoring. (4) Mentoring program: The mentoring program will train, educate and develop both mentors and mentees, using formative assessment with Six Sigma and 360° evaluation approaches for iterative improvement. (5) Technological advancements: It is anticipated that this COBRE with its engineering focus and device fabrication, should be able to push boundaries in musculoskeletal devices, especially with our technology transfer connection (CUBEInC). (6) Evaluation Plan: All components of the SC-TRIMH COBRE will use Six Sigma and 360° Evaluation approaches to improve every aspect. (7) Interface between clinicians and engineers: The interface between disciplines is the best place for innovations, thus facilitating interactions between diverse expertise, training, and scientific disciplines which has the greatest potential for biomedical advances.

概括 该管理员核心的使命是负责领导，整合和成功 为改善肌肉骨骼健康的南卡罗来纳州翻译研究实施 （SC-Trimh）。管理员核心主任是Hai Yao博士。 Martine Laberge博士担任副主任； 温莎·谢里尔（Windsor Sherrill）博士。和迈克尔·克恩（Michael Kern）博士完成4个成员执行委员会（EC）。一个 9位高级机构领导人和3-5的外部咨询委员会的内部咨询委员会 著名科学家将提供客观的监督，评估和战略互动，以优化中心的 影响。由7位医生组成的临床咨询委员会将深入了解临床问题，将重点关注 初级调查员（JI）研究，加上帮助提高创新并将机械理解为 翻译/临床益处。管理员核心的目的是：（1）提供有效的领导和 管理SC-Trimh，（2）通过建立严格的 使用“ 360°风格”评估过程使导师和Menee受益的程序，（3）启动飞行员 具有SC-TRIMH主题的项目计划，以吸引新的和/或已建立的调查人员，使他们能够 通过访问科学核心，心理和所有其他程序资源来生成初步数据 获得校外竞争研究奖的目标，以及（4） 用形成性和总结性方法的定期评估计划，以评估整个中心及其 组件零件。该管理员核心的创新特征包括：（1）虚拟人类试验（VHT），桥接 通过（i）计算机模拟的迭代过程，（ii）设备制造，台式和诊所之间的差距 和/或传感器植入，（iii）与动物或人尸体中的体内评估相结合。 （2）利用 工程专业知识，原则和实践的优势，以实现翻译的生物医学益处。 （3）指导团队：每个JI都有主要和中学的心理，所有SC-Trimh成员都将 成为增强和帮助这种心理的资源。 （4）指导计划：心理计划将训练， 使用六个Sigma和360°的形成性评估来教育和发展导师和MENETS 迭代改进的评估方法。 （5）技术进步：预计这是 鞋底具有工程重点和设备制造，应能够在 肌肉骨骼设备，尤其是我们的技术转移连接（Cubeinc）。 （6）评估计划： SC-Trimh Cobre的所有组件将使用六种Sigma和360°评估方法来改进 各个方面。 （7）临床医生与工程师之间的接口：学科之间的接口是最好的 创新场所，从而支持不同的专业知识，培训和科学学科之间的互动 这具有生物医学进展的最大潜力。