Development of Sustainable Reporting to the National COVID Cohort Collaborative (N3C)

为国家新冠肺炎队列协作组织 (N3C) 制定可持续报告

基本信息

批准号：
10244205
负责人：
ROBERT A CLARK
金额：
$ 9.99万
依托单位：
UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-22 至 2023-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10244205
关键词：
Address Administrative Supplement Affect Area Award Biomedical Research COVID-19 COVID-19 pandemic Cities Clinical Clinical Data Clinical Research Clinical Sciences Clinical Trials Clinical and Translational Science Awards Collection Communities Complex County Data Data Collection Data Coordinating Center Data Reporting Data Set Data Sources Development Diabetes Mellitus Doctor of Philosophy Effectiveness Electronic Health Record Ethnic Origin FAIR principles Fostering Frequencies Funding Future Generations Goals Grant Health Health Insurance Health Sciences Health Services Accessibility Healthcare Systems Hispanics Home environment Individual Infection Informatics Ingestion Institutes Institution Institutional Review Boards Investments Knowledge Learning Malignant Neoplasms Master&apos s Degree Medical Medicine Methods Military Personnel Minority Monitor Obesity Pathway interactions Patients Phenotype Population Population Heterogeneity Positioning Attribute Process Program Development Reporting Research Research Personnel Research Priority Resource Sharing Resources Rural Rural Population Science Services South Texas Specific qualifier value Students Sustainable Development TNFSF15 gene Texas Time Training Translating Translational Research Underrepresented Populations United States National Institutes of Health Universities Veterans Vision Work Workforce Development biomedical scientist care delivery care outcomes clinical encounter cohort coronavirus disease cost data access data acquisition data exchange data harmonization data hub data ingestion data sharing data submission data warehouse disparity reduction diverse data health disparity improved innovation interest metropolitan pandemic disease practice-based research network programs public health emergency response service member success translational scientist

项目摘要

Overall-Abstract San Antonio, positioned at the gateway to South Texas, is the 7th largest US city and the largest metropolitan area with a minority-majority population. Our 38-county region comprises an impoverished, rural, and largely Hispanic population with disproportionate rates of diabetes, obesity, and cancer, exacerbated by lack of health insurance and poor access to care. The region is home to major US military facilities, including the world’s largest military medical complex. Service members and veterans form populations with special needs. Neither better access to care nor improved care delivery, on their own, can eliminate health disparities. Innovative translational research is required to fill knowledge gaps and establish real-world effectiveness to improve health. In 2006, UT Health Science Center-San Antonio established the Institute for Integration of Medicine & Science (IIMS) as the academic home for our growing translational science initiatives, training the translational science workforce, formalizing key strategic partnerships, and creating a community of scholars within a learning healthcare system. We expanded clinical research programs, dramatically increasing access to clinical trials. We developed 6 Practice-Based Research Networks that focus on diverse ambulatory populations. We created 6 county-wide Translational Advisory Boards that support engagement through priority setting and matching with academic investigators. IIMS pioneered IRB process harmonization, resulting in rapid review times and streamlined pathways to multisite study initiation. We operate a robust pilot grant program, leveraged among our partners, with a remarkable return on investment. Our workforce development programs, with matriculants reflecting our diverse population, have graduated 133 masters degree students, supported 27 successful KL2 Scholars and 16 TL1 Scholars, and established de novo a Translational Science PhD program. Our informatics team has led electronic health record data warehouse development, fostering matches between IIMS investigators and practice-relevant research priorities. IIMS is now poised to deploy our robust portfolio of programs across our growing, leveraged, and innovative network of institutional and community partners. In this proposal, we provide clear strategies to support clinical and translational science across partner organizations, catalyze research team success, and implement programs that produce creative, collaborative, and culturally diverse translational scientists. IIMS seeks exceptionalism in translating scientific discoveries across the T1 to T4 spectrum into improved health care outcomes. Our over-arching Specific Aims are: 1. Accelerate clinical and translational research innovation and team science along the entire T1 to T4 research spectrum by providing an academic home integrated with our strategic partner institutions 2. Expand, diversify, and enhance the workforce of interdisciplinary translational biomedical scientists 3. Implement effective methods to continuously evaluate and optimize services, increase efficiencies, improve processes, endorse common metrics, and reduce costs across all IIMS programs

总体提取圣安东尼奥（San Antonio）位于通往德克萨斯州南部的门户，是美国第七大城市，最大的大都市地区，有少数群体人口。我们的38个县区包括一个贫穷的，糖尿病，肥胖和癌症发生不成比例的西班牙裔人口大致，加剧了由于缺乏健康保险和无法获得护理的机会。该地区是美国主要军事设施的所在地，包括世界上最大的军事医疗综合体。服务成员和退伍军人组成有特殊需要的人群。没有更好地获得护理的机会，也不能自行改善护理服务，无法消除健康差异。创新的需要翻译研究以填补知识空白并建立现实世界的有效性以改善健康。 2006年，UT健康科学中心安东尼奥建立了医学整合研究所科学（IIMS）是我们不断发展的转化科学计划的学术家园，培训翻译科学劳动力，格式化关键战略伙伴关系，并在学习中建立学者社区医疗保健系统。我们扩大了临床研究计划，大大增加了对临床试验的访问。我们开发了6个基于实践的研究网络，这些研究网络专注于潜水员的门诊人群。我们创建了 6县范围范围的翻译咨询委员会，通过优先设置并与学术研究人员。 IIMS开创了IRB流程的协调，导致了快速的审查时间和流线型多站点研究计划的途径。我们运营着一个强大的试点赠款计划，在我们的合作伙伴，具有惊人的投资回报。我们的劳动力开发计划，包括母亲反映我们的潜水员人口，已经毕业了133位硕士学位学生，并支持27个成功的KL2 学者和16个TL1学者，并建立了从头转化科学博士学位课程。我们的信息团队领导了电子健康记录数据仓库开发，促进了IIM之间的比赛研究人员和实践研究重点。 IIMS现在被中毒以部署我们强大的投资组合我们成长，杠杆和创新的机构和社区合作伙伴网络的计划。在此提案中，我们提供了明确的策略，以支持合作伙伴的临床和翻译科学组织，催化研究团队的成功并实施产生创造性，协作的计划，和文化多样的转化科学家。 IIM在翻译科学发现时寻求例外主义跨T1到T4频谱改善了医疗保健结果。我们整理的具体目的是： 1。加速临床和翻译研究创新和团队科学沿整个T1到T4 通过提供与我们的战略合作伙伴机构整合的学术房屋来提供的研究范围 2。扩展，多样化和增强跨学科转化生物医学科学家的劳动力 3.实施有效方法来连续评估和优化服务，提高效率，改善流程，认可通用指标并降低所有IIM计划的成本