CLINICAL TRIAL: ACTG 219: PEDIATRIC LATE OUTCOMES (AIDS)

临床试验：ACTG 219：儿科晚期结果（艾滋病）

• 批准号: 7718380
• 负责人: William Borkowsky
• 金额: $ 0.64万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7718380
• 关键词: AIDS clinical trial group; Acquired Immunodeficiency Syndrome; Anti-HIV Therapy; Child; Clinical; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Data; Disease; Disease Progression; Evaluation; Funding; Grant; HIV; Infant; Institution; Intervention; Laboratories; Morbidity - disease rate; Outcome; Quality-of-Life Assessment; Recording of previous events; Research; Research Personnel; Resources; Source; United States National Institutes of Health; design; follow-up; mortality; neurocognitive test; prophylactic; prospective; treatment effect

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. There is a need to better assess both positive and negative late consequences of the various anti-HIV therapies administered to children. This study is designed to collect prospective, longitudinal data to identify 1)late outcomes and consequences related to HIV disease progression, treatment or prophylactic intervention, and/or interaction of HIV disease and therapy and 2) late treatment effects among perinatally treated infants proven to be uninfected. Data will include history, quality of life assessment, physical exam, neurocognitive testing, clinical and laboratory evaluations, morbidity, and mortality. The study will last until the child reaches his/her 21st birthday or is lost to follow-up.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 中心，不一定是研究者的机构。 有必要更好地评估对儿童进行的各种抗艾滋病毒治疗的积极和消极的后期后果。本研究旨在收集前瞻性、纵向数据，以确定 1) 与 HIV 疾病进展、治疗或预防性干预和/或 HIV 疾病和治疗的相互作用相关的晚期结果和后果，以及 2) 经证明在围产期治疗的婴儿中的晚期治疗效果不被感染。数据将包括病史、生活质量评估、体检、神经认知测试、临床和实验室评估、发病率和死亡率。研究将持续到孩子年满 21 岁或失访为止。