Diabetes Research Center

糖尿病研究中心

基本信息

批准号：
10077833
负责人：
Steven Emanuel Kahn
金额：
$ 138.82万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-02-10 至 2022-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10077833
关键词：
Area Basic Science Biological Assay Biomedical Research Body Weight CRISPR/Cas technology Cell Culture Techniques Cell physiology Cells Clinical Research Clinical Trials Communities Complications of Diabetes Mellitus Computerized Medical Record Data Analyses Development Diabetes Mellitus Diabetes prevention Direct Costs Discipline Disease Ensure Etiology Faculty Fellowship Financial Support Fostering Functional disorder Funding Generations Genes Goals Grant Histopathology Human Immunohistochemistry Institution Insulin-Dependent Diabetes Mellitus Investigation Islet Cell Mass Spectrum Analysis Mediating Metabolic Mission Morphology Mus National Institute of Diabetes and Digestive and Kidney Diseases Non-Insulin-Dependent Diabetes Mellitus Obesity Pathogenesis Peer Review Performance Phenotype Prevention Proteomics Regulation Research Research Activity Research Methodology Research Personnel Resources Scientist Services Technology Training Transgenic Animals Transgenic Mice Translating Translations United States National Institutes of Health Universities Virus Wages Washington base care outcomes cellular imaging clinical care clinical investigation collaborative environment complex data epidemiology study faculty support glucose metabolism graduate student human subject improved in vivo innovation laser capture microdissection lectures metabolic phenotype molecular imaging prevent programs recruit response symposium tool vector

项目摘要

The Diabetes Research Center at the University of Washington has existed for over four decades and is part of the national program supported by NIDDK. It acts as the focal point and umbrella for diabetes research in the Greater Seattle area with the goal of promoting an environment of collaborative research on diabetes, obesity and related disorders by (1) Providing support to affiliate investigators through its biomedical research cores; (2) Conducting a pilot and feasibility program that provides grant support for new investigators in diabetes research and to established investigators in other disciplines; (3) Sponsoring an interactive enrichment program comprising lectures, retreats and symposia to inform the community of the latest developments in the area; (4) Ensuring the development of young investigators by providing postdoctoral and graduate student fellowships for salary support and training in its biomedical research cores; and (5) Developing new research methods and technologies based on the evolving needs of its investigators. To accomplish this goal, the Center is organized around five biomedical research cores (Cell Function Analysis Core, Cellular and Molecular Imaging Core, Human Studies Core, Quantitative and Functional Proteomics Core, and Vector and Transgenic Mouse Core) and an Administrative Core that also manages the Pilot and Feasibility Program and the Enrichment Program. Along with the commitment of the University of Washington and other Seattle institutions of research space and additional financial support, the Diabetes Research Center is a dynamic and constantly evolving center that supports 99 Seattle-based affiliate investigators who are making important scientific contributions in the areas of (1) Pathophysiology, prevention and treatment of type 2 diabetes; (2) Central regulation of body weight and glucose metabolism; (3) Complications of diabetes; (4) Etiology, pathogenesis and treatment of type 1 diabetes; and (5) Clinical trials and large-scale epidemiologic studies.

华盛顿大学的糖尿病研究中心已经存在了四十年，是 NIDDK支持的国家计划。它是糖尿病研究的焦点和伞大西雅图地区的目标是促进有关糖尿病，肥胖的协作研究环境（1）通过其生物医学研究核心为会员研究人员提供支持；（2）进行一项飞行员和可行性计划，为糖尿病的新调查人员提供赠款支持研究和其他学科的研究人员；（3）赞助交互式富集包括讲座，务虚会和专题讨论会的计划，以告知社区区域; （4）通过提供博士后和研究生来确保年轻研究人员的发展在其生物医学研究核心中获得薪水支持和培训的奖学金；（5）发展新研究基于研究人员不断发展的需求的方法和技术。为了实现这一目标，中心在五个生物医学研究核心周围组织（细胞功能分析核心，细胞和分子成像核心，人类研究核心，定量和功能蛋白质组学核心以及载体以及转基因鼠标核心）和一个管理核心，该核心还管理了飞行员和可行性程序和丰富计划。以及华盛顿大学和其他西雅图的承诺研究空间的机构和额外的财务支持，糖尿病研究中心是一种动态，不断发展支持99位基于西雅图的会员调查人员的中心（1）病理生理学，2型糖尿病的预防和治疗领域的科学贡献；（2）体重和葡萄糖代谢的中心调节；（3）糖尿病并发症；（4）病因， 1型糖尿病的发病机理和治疗；（5）临床试验和大规模流行病学研究。