Organic Synthesis

有机合成

• 批准号: 10084824
• 负责人: Ouathek Ouerfelli
• 金额: $ 42.05万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-01-20 至 2023-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10084824
• 关键词: Biology; Cancer Center Support Grant; Cancer Detection; Chemicals; Chemistry; Communities; Consultations; Custom; Development; Experimental Designs; Formulation; Human Resources; Lead; Medicine; Methods; Mission; Organic Synthesis; Pharmaceutical Chemistry; Phase I Clinical Trials; Prevention; Procedures; Research Personnel; Services; Therapeutic Agents; Work; Writing; chemical synthesis; lead candidate; member; novel; preclinical study; tool

ABSTRACT MSK is committed to the discovery and development of new tools and therapeutic agents for cancer detection, prevention, and treatment. The mission of the Organic Synthesis Core is to provide chemical synthesis services to Center members through a state-of-the art facility staffed by expert professional personnel in chemical synthesis. The Core operates at the interface of chemistry, biology, and medicine, and has the capability of supporting medicinal chemistry efforts to produce and evolve lead candidates and tool compounds in support of Center investigators. The work of the Core has greatly facilitated preclinical studies at the Center. The Core synthesizes novel molecules that are not readily available, by either following described procedures, or by developing new and more suitable methods of synthesis.

抽象的 MSK致力于发现和开发用于癌症检测的新工具和治疗剂， 预防和治疗。有机合成核心的任务是提供化学合成 通过由专业专业人员组成的最先进的设施为中心成员提供服务 化学合成。核心在化学，生物学和医学的界面上运作，并具有 支持药物化学努力的能力，以生产和发展铅候选和工具化合物 支持中心调查员。核心的工作极大地促进了该中心的临床前研究。 核心合成了不容易获得的新型分子，这是通过以下任何描述的程序， 或通过开发新的，更合适的合成方法。