Annual Adult Changes in Thought (ACT) symposium on aging, dementia, and Alzheimer's disease

关于衰老、痴呆和阿尔茨海默病的年度成人思想变化 (ACT) 研讨会

• 批准号: 10066181
• 负责人: Eric B Larson
• 金额: $ 5万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10066181
• 关键词: Adult; Aging; Alzheimer' s Disease; Alzheimer' s Disease patient registry; Alzheimer' s disease brain; Alzheimer' s disease related dementia; British; Clinical; Collaborations; Communities; Consultations; DNA; Data; Dementia; Discipline; Disease; Early Diagnosis; Elderly; Equipment; Evaluation; Feedback; Funding; Future; Grant; Image; Infrastructure; Institution; Internal Medicine; International; Journals; Laboratories; Learning; Medical; Medicine; Methods; Mind; Minority Groups; National Institute on Aging; Neurobiology; Neurology; New England; Paper; Prevention; Principal Investigator; Publishing; Research; Research Personnel; Resources; Scientist; Time; Traumatic Brain Injury; Travel; Underrepresented Minority; Universities; Washington; Woman; Work; aging brain; brain tissue; data sharing; human old age (65+); innovation; molecular phenotype; research study; resilience; symposium; trend

Project Summary/Abstract Nearly 6 million U.S. adults are currently living with Alzheimer’s disease (AD), and 700,000 of these people will die in 2019 alone. There is no simple solution for prevention, early detection, or cure. Since 1994, the Adult Changes in Thought (ACT) study has collected observational, clinical, and laboratory data on more than 5,500 older adults and is following them over time for signs of dementia and Alzheimer’s disease. ACT data contribute to a living, learning laboratory, which serves as a scientific resource for the research community. For the past seven years, we have held an annual ACT symposium to showcase new ACT resources, highlight innovative research findings, share new grant ideas, and promote cross-disciplinary collaborations. Every year we have received higher ratings on our post-symposium evaluations, with 98% of last year’s attendees indicating they would recommend the symposium to others and 100% indicating they would attend a future ACT symposium. However, we do not have the capacity to hold future symposia without conference grant funding. This conference grant will provide support to continue and grow the ACT symposia over the next five years. The specific objectives of our conference grant are to: 1) promote scientific use and understanding of ACT data; 2) promote collaborations across scientific disciplines, institutions, and studies; and 3) provide opportunities for feedback on ongoing and planned work such as analyses-in-progress or new grant ideas, particularly for junior investigators. This funding will allow us to host the symposium in a large, accessible venue with advanced audiovisual equipment. It also will provide travel stipends for junior researchers, investigators from underrepresented minority groups, and researchers traveling from out of town so that we may extend our reach to new external investigators. Future conferences will cover critical topics in aging and dementia research such as resilience, imaging, dementia subtypes, molecular phenotypes, traumatic brain injury, and others. Long term, continuing and expanding the ACT symposia will increase use of the ACT living laboratory and provide a creative, welcoming space for top investigators to exchange innovative research ideas and accelerate AD and brain aging research.

项目摘要/摘要 目前有近600万美国成年人患有阿尔茨海默氏病（AD），其中700,000人将 仅在2019年就死亡。没有简单的解决方案用于预防，早期检测或治愈。自1994年以来，成人 思想变化（ACT）研究已收集了超过5500多个的观察，临床和实验室数据 老年人，随着时间的流逝，他们正在痴呆和阿尔茨海默氏病的迹象。 ACT数据 为生活实验室做出贡献，该实验室是研究界的科学资源。为了 在过去的七年中，我们举办了年度ACT研讨会来展示新的ACT资源，突出显示 创新的研究结果，分享新的赠款思想并促进跨学科的合作。每年 我们在群岛后评估中获得了更高的评级，去年的参与者中有98％ 表明他们会向其他人推荐研讨会，100％表明他们将参加未来 ACT研讨会。但是，如果没有会议赠款，我们就没有能力举行未来的研讨会 资金。这项会议赠款将为继续在接下来的五个 年。我们会议赠款的具体目标是：1）促进科学用途和理解 ACT数据； 2）促进跨科学学科，机构和研究的合作； 3）提供 正在进行的反馈和计划工作的机会，例如进行分析或新的赠款创意， 特别是对于初级调查人员。这笔资金将使我们能够在大型，可访问 带有高级视听设备的场所。它还将为初级研究人员提供旅行压力， 来自代表性不足的少数群体的调查人员和从外地旅行的研究人员，以便我们 可能会将我们的影响力扩展到新的外部调查人员。未来会议将涵盖衰老和 痴呆研究，例如弹性，成像，痴呆症亚型，分子表型，创伤性大脑 受伤和其他人。长期，继续和扩大该法案座谈会将增加对行为生活的使用 实验室并为顶级调查人员提供创新的创新研究的创造性，热情的空间 想法和加速AD和大脑衰老研究。