Center Core Grant for Vision Research
视觉研究中心核心资助
基本信息
- 批准号:10018326
- 负责人:
- 金额:$ 61.6万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-01 至 2025-08-30
- 项目状态:未结题
- 来源:
- 关键词:Allied Health SciencesAwardBasic ScienceBlindnessCenter Core GrantsClinicalCollaborationsCommunicationCore GrantDentistryDevelopmentDiseaseDoctor of PhilosophyEnsureEquipmentFinancial SupportFundingGene ExpressionGoalsGrantGroup MeetingsHealth SciencesHealthcareHistologyHuman ResourcesImageInfrastructureInstitutesInstitutionInvestigational TherapiesLaboratoriesMethodologyMissionNamesOphthalmologistPatientsPilot ProjectsProductivityProteomicsResearchResearch PersonnelResearch Project GrantsResearch SupportResourcesSchool NursingScientistSeriesServicesTalentsTechnologyTimeTravelUniversitiesVisionVision DisordersVision researchVisual system structureclinically relevantcohortcollegefaculty researchinstrumentationinvestigator trainingmedical schoolsprogramsrecruitsuccessundergraduate studentvision science
项目摘要
Overall: Project Summary
The vision science group at Augusta University/Medical College of Georgia is known collectively as the James
and Jean Culver Vision Discovery Institute (Culver VDI). The mission of the Culver VDI is to engage in high
impact research and discovery for patients suffering from blindness and visual disorders. Within this group of
basic science researchers and ophthalmologists are 22 investigators who direct 15 NEI R01s, 2 NEI R21s and
1 NEI K99. The objective of the center core grant for vision research is (1) to provide crucially needed
expertise and instrumentation to enhance the research programs of these talented investigators and (2) to
promote collaborations within the group and with scientists across the nation. To achieve this mission, we have
organized facilities, services and shared instrumentation into the following three modules: (1) Visual Function
Assessment; (2) Histology and Imaging; (3) Gene Expression/Proteomics. These modules provide research
resources, services and shared instrumentation that are essential to the success of ongoing projects in multiple
laboratories. Support of these modules will boost development of new projects and enhance collaborations
bringing the best of the latest technology to our NEI-funded research. Augusta University is committed to vision
science and to the Culver VDI, which launched in 2008. Since that time, the University has supported
recruitment of 11 vision research faculty with competitive start-up packages and laboratory space across
multiple departments and colleges. The University has sponsored clinically-relevant pilot projects and travel
awards for trainees, assisted with the purchase of sophisticated instrumentation and facilitated
collaboration/communication through the support of a robust seminar series, an annual retreat and monthly
group meetings. Support is requested in the form of this Center Core Grant for Vision Research to achieve the
following aims: Aim 1. To provide support for module personnel who assist and train investigators and their
staff in the use of sophisticated instrumentation and methodology. Aim 2. To provide select services thereby
enhancing productivity of Augusta University vision researchers and avoiding unnecessary duplication of
equipment/effort. Aim 3. To ensure continued productivity of outstanding clinically-relevant vision research by
assisting: a) established and first-time NEI R01-funded investigators, b) established NEI R01-funded
investigators who seek to renew their NEI-funded projects or develop new vision-related projects, c) scientists
from other fields who bring their scientific expertise to the fields of vision research.
总体:项目摘要
奥古斯塔大学/佐治亚州医学院的视觉科学小组被称为詹姆斯
和让·卡尔弗(Jean Culver)视觉发现研究所(Culver VDI)。 Culver VDI的任务是高高参与
影响患有失明和视觉障碍的患者的研究和发现。在这一组中
基础科学研究人员和眼科医生是22位指导15个NEI R01,21个NEI R21和的研究人员
1 NEI K99。视觉研究中心核心赠款的目的是(1)提供至关重要的需求
专业知识和工具,以增强这些才华横溢的研究人员的研究计划,以及(2)
促进该小组内部的合作,并与全国各地的科学家进行合作。为了实现这一任务,我们有
有组织的设施,服务和共享仪器到以下三个模块中:(1)视觉功能
评估; (2)组织学和成像; (3)基因表达/蛋白质组学。这些模块提供了研究
资源,服务和共享工具对于多个项目的成功至关重要
实验室。这些模块的支持将促进新项目的开发并增强合作
将最新技术的最佳技术带入我们的Nei资助研究。奥古斯塔大学致力于远见
科学和到2008年推出的Culver VDI。从那时起,大学支持
招募11个视力研究教师,具有竞争性的启动套餐和实验室空间
多个部门和大学。该大学赞助了与临床相关的试点项目和旅行
学员的奖项,协助购买复杂的乐器并提供便利
通过支持强大的研讨会系列的支持/沟通,年度务虚会和每月一次
小组会议。以此中心核心赠款的形式要求提供支持,以实现愿景研究
以下目的:目标1。为支持和培训调查人员及其培训的模块人员提供支持
使用复杂仪器和方法论的工作人员。目标2。提供精选服务
提高奥古斯塔大学愿景研究人员的生产力,并避免不必要的重复
设备/努力。目标3。确保通过
协助:a)建立和首次由NEI R01资助的调查人员,b)建立了NEI R01资助
试图续签其新资助的项目或开发与新愿景相关的项目的调查人员,c)科学家
来自其他领域,这些领域将科学专业知识带入视力研究领域。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Sylvia B. Smith其他文献
C57BL/6J-vit/vit mouse model of retinal degeneration: light microscopic analysis and evaluation of rhodopsin levels.
- DOI:
10.1016/0014-4835(92)90017-m - 发表时间:
1992-12 - 期刊:
- 影响因子:3.4
- 作者:
Sylvia B. Smith - 通讯作者:
Sylvia B. Smith
JPET #57109 1 Transport of Amino acid-based Prodrugs by the Na- and Cl- coupled Amino Acid Transporter ATB and Expression of the Transporter in Tissues Amenable for Drug Delivery
JPET
- DOI:
- 发表时间:
2003 - 期刊:
- 影响因子:0
- 作者:
Takahiro;Hatanaka;Masayuki;Haramura;You;Fei;Seiji;Miyauchi;C. Bridges;Preethi S. Ganapathy;Sylvia B. Smith;V. Ganapathy;M. E. Ganapathy - 通讯作者:
M. E. Ganapathy
Late-onset cerebellar degeneration in mice induced transplacentally by methylnitrosourea.
甲基亚硝基脲经胎盘诱导小鼠迟发性小脑变性。
- DOI:
10.1002/tcm.1770070503 - 发表时间:
1987 - 期刊:
- 影响因子:0
- 作者:
Sylvia B. Smith;Cathy B. Brown;Mary E. Wright;K. Lemone Yielding - 通讯作者:
K. Lemone Yielding
Regulation of Reduced-Folate Transporter-1 in Retinal Pigment Epithelial Cells by Folate
叶酸对视网膜色素上皮细胞中还原叶酸转运蛋白 1 的调节
- DOI:
10.1080/02713680490894559a - 发表时间:
2005 - 期刊:
- 影响因子:2
- 作者:
Hany Naggar;Tracy K Van Ells;V. Ganapathy;Sylvia B. Smith - 通讯作者:
Sylvia B. Smith
The Impact of Diabetes on Neuronal, Glial, and Vascular Cells of the Retina
糖尿病对视网膜神经元、胶质细胞和血管细胞的影响
- DOI:
10.1007/978-1-59745-186-4_9 - 发表时间:
2007 - 期刊:
- 影响因子:3.7
- 作者:
Sylvia B. Smith - 通讯作者:
Sylvia B. Smith
Sylvia B. Smith的其他文献
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{{ truncateString('Sylvia B. Smith', 18)}}的其他基金
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